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Publishing Tissue Transplantation in New York Title: J. V. Linden, T. J. Favreau, D. M. McKendree; Author Wadsworth Center, New York State Department of Health, Albany, NY. Block: Background: In order to transplant or otherwise clinically use tissue in New York (NY), a health care facility or medical office must hold a NY license as a Transplantation Facility. Licensed Transplantation Facilities are required to report the volume of their tissue transplantation activities annually, including both the number of tissue allografts used and the number of recipients. Methods: Aggregate data regarding the number of tissue allografts in NY were tabulated from Transplantation Facility reports for 2006, the most recent year available. Aggregate figures were tabulated based on the type of health care site acute care hospital (on either an inpatient or outpatient basis) or non-hospital setting, which included ambulatory surgery centers and physicians' offices. The mean number of allografts used per patient was determined by dividing the number of unique recipients into the total number of allografts used. The population of NYS, according to Census and vital status data, was used to calculate transplantation rates per 1,000,000 population per year. Results: The vast majority of tissue allografts (non-reproductive) were transplanted in a hospital setting (musculoskeletal [MS] 98%, cardiovascular [CV] 87%, skin 96%), with the exception of eye surgery, for which hospitals used 70% of corneas, 71% of scleral grafts, and 79% of amniotic membrane. Amniotic membrane was used only for eye surgery. The only CV tissue used in the non-hospital setting was pericardium, which was used only for eye surgery. Skin was used at hospitals, ambulatory surgery centers, and wound treatment centers.

Tissue Allografts Transplanted in NY, 2006 Type of Tissue

Abstract Body:

Non-Hospital (N=64) # Grafts/ # Recipients 686/ 676 118/ 118 233/ 211 644/ 644 123/ 123

Hospital (N=202) # Grafts/ # Recipients

Total Mean # Grafts per Recipient 1.03 1.29 1.002 1.002

# Grafts per 1,000,000 Pop 1,631 48 317 113 23

MS CV Skin Cornea Sclera

30,295/ 24,407 1.24 798/ 779 5,788/ 4,440 1,494/ 1,490 307/ 306

Amniotic 87/ 86 337/ 333 1.012 22 Membrane Conclusions: Because data regarding actual use of tissue allografts in a given population are very limited, the data collected from transplantation facilities in NY provide valuable information on the number of allografts used and in what type of health care facility, as well as the average number of grafts per patient. In 2006, 97% of deceased donor allografts were used at hospitals, but approximately 30% of eye surgery that required allograft tissue was performed in a non-hospital setting. Such sites may be less likely than hospitals to be accredited by a standards-setting organization with tissue-handling standards, such as The Joint Commission. A limitation of these observations is that dental offices are not included. Future studies comparing data from different years will be necessary to assess trends over time.

Author Disclosure J.V. Linden, None. Block:


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