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Box-Behnken Design

For three factors, the design is Trial 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 A + + ­ ­ + + ­ ­ 0 0 0 0 0 0 0 B + ­ + ­ 0 0 0 0 + + ­ ­ 0 0 0 C 0 0 0 0 + ­ + ­ + ­ + ­ 0 0 0

where + is the high value, ­ is the low value and 0 is the center value. Designs exist for other numbers of factors. Number of Factors 3 4 5 6 7 Number of Experiments (with 3 replicates at center) 15 27 46 54 62

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Box-Behnken Design

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