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CENTRAL COUNCIL FOR RESEARCH IN AYURVEDA AND SIDDHA ADDRESS LIST OF INSTITUTES/CENTRES AND THEIR ACTIVITIES Sl.No. Name of the Unit Telephone Nos. 25229128,25221059 25225546(Telefax) · E-mail: [email protected] [email protected] · · · · · · · · · Area of Research · Amavata (Rheumatoid arthritis) Medoroga (Lipid disorders) Vyanabala VaisHamya (Hypertension) Arsa (Piles) Bhagandara (Fistula-in-ano) Apasmara (Epilepsy) Pakshaghata(Hemiplegia) Gridhrasi (Sciatica) Madhumeha (Diabetes mellitus) Dristidosh (Myopia) Pandu (Iron Anaemia) Deficiency

1 Asstt-Director -InCharge Central Research Institute (Ay.), Road No.66, Punjabi Bagh New Delhi -110026

2 Director (Institute) Central Research Institute (Siddha), A.A. Govt. Hospital Campus, Arumbakkam, Chennai-600106

044/26214809(O) 26214925(G) 26631428 (R) Mobile:09444293642 E-mail: [email protected]

· · · · · · · · ·

Putrunoi (Cancer) Kalanjagapadai (Psoriasis) Santhu vath Soolai (Rheumatoid arthritis) Manjal kamalai (Infective hepatitis) Venpadai (Vitiligo) Neerzhivu (Diabetes mellitus) Valigunmam (Peptic ulcer) Velluppunoi (Iron Deficiency Anaemia)

3 Research Officer Incharge Central Research Institute (Ay.) RA Podar College, Worli, Mumbai-

022/24947822(Telefax) 022/24947833 (O) Mobile:9820561496 E-mail: [email protected]

· · · ·

Amavata (Rheumatoid arthritis) Visamajvara (Malaria) Medoroga (Lipid disorders) Vyanabala Vaisamya

400018 · · ·

(Hypertension) Arsa (Piles) Bhagandara (Fistula-in-ano) Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Medoroga (Lipid disorders) Vyanabala Vaisamya (Hypertension) Arsa (Piles) Bhagandara (Fistula-in-ano) Apasmara (Epilepsy) Madhumeha (Diabetes mellitus) Parinamasula (Duodenal ulcer) Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Vyanabala Vaisamya (Hypertension) Pangu (Paraplegia) Kitibha (Psoriasis) Pakshaghata(Hemiplegia) Gridhrasi(Sciatica) Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Slipada (Filariasis) Vyanabala Vaisamya (Hypertension) Arsa (Piles) Bhagandara (Fistula-in-ano) Tamaka swasa (Bronchial Asthma) Pakshaghata(Hemiplegia) Parinamasula (Duodenal ulcer) Madhumeha (Diabetes mellitus) Kitibha (Psoriasis)

4 Director Incharge, National Institute of Drug Development, 4 CN Block, Sector V, Bidhan Nagar Kolkata-700091

033/23673808(Telefax) 23673881 Mobile:09830054142 E-mail: [email protected]

· · · · · · · · ·

5 Assistant Director Incharge Central Research Institute of PanchKarma , Cheruthuruthy, Via Shoranur, Trichur Distt, Kerala679531

04884/262366(Telefax) 262543(O) 262544(H) 0466/2222125(R) M:09447443275 E-mail: [email protected]

· · · · · · ·

6 Assistant Director Incharge Central Research Institute (Ay.), Unit No.1 Bhubaneswar751009

0674/2530125 (Telefax) 2531941 (H) 2432726 (R ) Mobile: 09437284618 E-mail: [email protected] .in

· · · · · · · · · ·

· 7 AD -Incharge, National Institute of Ayurveda Pharmaceutical Research Moti Bagh Road, Patiala-147001 0175/2212393 (Telefax) 2228361 (Hospital) 2212348 (R) Mobile: 3111361 E-mail: [email protected]

Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Manodvega (Anxiety Neurosis) Vyanabala Vaisamya (Hypertension) Medo roga (Lipid disorders) Tamaka swasa (Bronchial Asthma) Pakshaghata (Hemiplegia) Kitibha (Psoriasis) Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Grahani roga (Mal-absorption syndrome) Vyanabala Vaishamya (Hypertension) Arsa (Piles) Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Manodvega (Anxiety Neurosis) Arsa (Piles) Medo roga (Lipid disorders) Gridhrasi(Sciatica) Kamala (Jaundice) Pandu (Iron Deficiency Anaemia)

· · · · · · · ·

8 RO -Incharge Central Research Institute (Ay.), Govt. Ayurvedic Hospital, Amkho, Gwalior-474009

0751/2323307(Telefax) 2430317 (Fax) 2327959 (R) E-mail: [email protected]

· · · · ·

9 Research Officer Incharge Central Research Institute (Ay.) 474/6, Sitapur Road, Lucknow-220602

.0522/2369156 (Telefax) · 2362341 Email · [email protected] m · · · · · 0141/2281812 2282618 (Telefax) 2205098 ( R) E-mail: [email protected]

10

Director , Central Research Institute (Ay.), Indira Colony, Jhotwara, Bani Park, Jaipur-320016

Amavata (Rheumatoid arthritis) · Visham Jvara (Malaria) · Tamaka swasa (Bronchial Asthma) · Pandu (Iron Deficiency Anaemia) ·

11 Assistant Director Incharge, Regional Research Institute (Ay) 1044-Jagnade Chowk, KDK College Road, Nandanwan, Nagpur-440009

0712/2714230 (Telefax) 5624478 (R) 9422111851 (M) E-mail: [email protected]

· · · · ·

Amavata (Rheumatoid arthritis) Vyanabala Vaisamya (Hypertension) Pangu (Paraplegia) Pakshaghata (Hemiplegia) Pandu (Iron Deficiency Anaemia)

12 RO-Incharge, Regional Research Instt. (Ay.), Govt. Central Pharmacy Annexe, Ashoka Pillar, Jayanagar Bangalore-560011

080/26562030 (Telefax) 2272208 (R) 9845231056 (M) E-mail: [email protected]

Arsa (Piles) Manodvega (Anxiety Neurosis) · Vyanabala Vaisamya (Hypertension) · Tamaka swasa (Bronchial Asthma) · Pandu (Iron Deficiency Anaemia) · · · · · · Amavata (Rheumatoid arthritis) Kitibha (Psoriasis) Mutrasmari (Urinary Calculi) Pandu (Iron Deficiency Anaemia) Amavata (Rheumatoid arthritis) Slipada (Filariasis) Tamaka swasa (Bronchial Asthma) Parinamasula (Duodenal ulcer)

13 Assistant Director Incharge, Regional Research Instt.(Ay.), Poojapura

0471/2340628 (O) 2342070 (Fax), 2355119 (Res.) Mobile:9447861934 E-mail: [email protected]

Thiruvananthapuram695012 14 Assistant Director Incharge, Regional Research Instt.(Ay.), Indira Gandhi Municipal Stadium Complex A, First Floor, North Wing Vijayawada-520010 15 AD-Incharge Regional Research Institute (Siddha) Chellaperumal Street Kuyavarpalayam Pondicherry-605006 0866/2472535 (Telefax) 2437521 (R) E-mail: [email protected] [email protected]

· · · ·

0413/2245072 (Telefax) 2344580 (Res.) E-mail: [email protected]

Vathasoolai (Arthritis) Venpadai (Vitiligo) Neerazhivu (Diabetes mellitus) · Velluppunoi (Iron Deficiency Anaemia) · · ·

16 Research Officer Incharge, Regional Research Instt. (Ay.), D Block, Rajindra Memorial Res. Institute Building, Agam Kuan, Patna-800007 17 AD-Incharge Regional Research Instt. (Ay.), Borsojai (Bhetapara), Beltola, Guwahati-781028, Assam 18 RO Incharge, Regional Research Instt. (Ay.), Tadung, Gangtok, Sikkim-737102 1919 Research Officer Incharge, Regional Research Institute (Ay.) New Itanagr-791111 (Arunachal Pradesh)

0612/2631678(Telefax)

· · · · · ·

Amavata (Rheumatoid arthritis) Vishama jvara (Malaria) Tamaka swasa (Bronchial Asthma) Arsa (Piles) Slipada (Filariasis) Gridhrasi(Sciatica) Mutrasmari (Urinary Calculi) Medo roga (Lipid disorders)

0361/2303714

· ·

03592/231494 (Telefax)

· ·

Grahani roga (Malabsorption syndrome) Gridhrasi(Sciatica)

0360/212284 (Telefax) 211498 (O) 212520 (R)

· · · · · ·

Amavata (Rheumatoid arthritis) Vishama jvara (Malaria) Vyanabala Vaisamya (Hypertension) Mutrasmari (Urinary Calculi) Gridhrasi (Sciatica) Madhumeha (Diabetes mellitus) Amavata (Rheumatoid arthritis) Mutrasmari (Urinary Calculi) Vyanabala Vaisamya (Hypertension) Arsa (Piles) Kitibha (Psoriasis) Medo roga (Lipid disorders)

20 Research Officer Incharge, Regional Research Institute (Ay.), 20, Rewari Chowk, Jammu-180005

0191/2546475(Telefax) 2573191 (R)

· · · · · ·

21 Research Officer Incharge, Regional Research Institute (Ay.), Gandhi Bhawan, Mandi-175001

01905/235236(Telefax)

Amavata (Rheumatoid arthritis) · Arsa (Piles) ·

(Himachal Pradesh) 22 Research Officer Incharge, Regional Research Institute (Ay.), Tarikhet-263663 (Uttaranchal) 05966/264227(Telefax) 220330 (Garden) 264222 (R) E-mail: [email protected] · · · · · Medico-Ethno-Botanical Survey of Medicinal Plants Saffron Garden Musk deer Farm

23 Research Officer In05174/2442132(Telefax) charge, Regional Research Institute (Ay.), Gwalior Road, Jhansi284003 (U.P.) 24 AD-Incharge 079/27471574 (R) Institute of Ayuevda Drug Research, Mobile:9825339833(Dr. Block 0/3, Building Rawal) Mental Hospital Campus, Meghani nagar Ahmedabad

Amavata (Rheumatoid arthritis) · Vyanabala Vaisamya (Hypertension) Amavata (Rheumatoid arthritis) · Tamaka swasa (Bronchial Asthma) · Vyanabala Vaisamya (Hypertension) · Mutrasmari (Urinary Calculi) · · · Medico-historical Research with special reference to ISM Survey, collection & preservation of source material of ISM of various types of manuscripts, archeological, epigraphical etc. Study on evolution of disease & drugs Re-writing history of ISM using objective & scientific medico-historical researches Publication of the Institute's Bulletin on History of Medicine periodically In-depth study and critical translation of selected manuscripts To develop teaching & training kits/aids for history of Medicine in India

25 Director In-charge, Indian Institute of History of Medicine, Osmania Medical College Buildings Putlibowli, Hyderabad500095

040/24657388(Telefax) 27207657 (R) 24746523 (Fax) Mobile:9848275965 E-mail: [email protected] [email protected]

· ·

· · ·

·

26

Director , CSMDRIA, A.A. Govt. Hospital Campus, Arumbakkam, Chennai600106

044/26214823 (O) 26207566 (O) 26153187 (R) E-mail: [email protected]

27 Project Officer, Dr. A. Lakshmipati Research Centre for Ayurveda, VHS Medical Centre, Adyar, Chennai-600113 28. Assistant Director Incharge Ayurvedic Research Unit, NIMH&NS, Hosur Road, Bangalore-560029

044/2541537 E-mail: [email protected]

Drug standardization Phytochemistry Pharmacology Biochemistry Microbiology RCH Project ISM Project Medo roga (Lipid disorders) · Vishama jvara (Malaria) · Vyanabala Vaisamya (Hypertension) · · · · · · · ·

080/26567546 (O) 26995243 (Direct) 26571225 (R ) E-mail: [email protected] n

Apasmara (Epilepsy) Manasmandata (Mental Retardation) · Manodvega (Anxiety Neurosis) · Unmada (Schizophrenia) · Mamsavata (Muscular Dystrophy) · · Cultivation of Medicinal Plants · Pharmacognosy Research · Plant Tissue culture ·

29. Research Officer Incharge, Regional Research Institute (Ay.), JNAMPG&H, Kothrud, Nehru Garden, Pune.-411038 30. Project Officer, Clinical Research Unit (Siddha) Govt. Siddha Medical College, Palayamkottai-627002 Tirunelveli Distt. (Tamil Nadu) 31. The Project Officer, Clinical Research Unit (Siddha), Santhigiri Siddha Medical College, Thiruvananthapuram

020-2583138(O) 020-25386715(O) 020-25390857(R) E-mail: [email protected]

0462/2572736 2580845 (Fax) 2579841 (Fax)

· · · ·

Keel Vayu (Arthritis) Karappan (Eczema) Moolam (piles) Velluppunoi (Iron Deficiency Anaemia) Pharmacovigilance study on Ayurveda and Siddha practices

·

32

Research Officer Incharge, Tribal Health Care Research Project, Car Nicobar-744301 Research Officer Incharge, Sowa Rigpa (Amchi) Research Centre, Leh-194101

03193/265211(0) 265212 (R)

·

Tribal Health Care Programme

33.

01982/252449 264054 (R)

·

Hypertension

Annexure-II DETAILS OF COLLABORATIVE RESEARCH From the very beginning CCRAS is carrying out its research activities through ISM Institutions/Hospitals in collaboration with modern medical Institute/Hospital. Council is having linkages with modern Institutions like Industrial Toxicological Research Centre, Lucknow, Central Drug Research Institute, Lucknow, National Institute of Nutrition, Hyderabad, Indian Institute of Chemical Technology, Hyderabad, T.N. Medical College, Mumbai for pharmacological and toxicological studies of research drugs. A collaborative clinical research study on Bronchial asthma is in progress with NAAMI Medical Centre, Moscow, Russia. Many multicentric studies are also being conducted through modern Institutions/Hospitals. Some other collaborative research trials which are finalized/on going are as follows:

S.No. 1

CCRAS Institutes CCRAS Head Quarters

Collaborating Institutions AMUL, Gujarat

Research Area To develop Nutritional supplement for · School going Children, · Pregnant women · Geriatric population (In progress) 1. Analytical study of Bhasmas (Rasmanikya) 2. Project entitled, "Synthesis Characterization, toxicity studies and clinical trials of Bhasmas-a Comprehensive study" (In progress) Atomization of Panchakarma Equipments · Shirodhara & Kshara sutra-Completed · Sarvanga Dhara-(In progress) Efficacy of Manasamitram Vadakam on Generalized Anxiety Disorder: A polysomnographic Study -(In progress) Apasmar (Epilepsy), Manas Mandata (Mental Retardation) Anxiety Neurosis, Kampawat (Parkinsonism), Mamsashosh (Muscular Dystrophy)(protocol finalization is in progress)

2

RRIA, Kothrud, Pune

Bhide foundation Pune

3

CCRAS Hqrs / CRI, NEW DELHI

IIT, New Delhi

4

Clinical Research Unit, Banglore

NIMHANS, Banglore

5

Central Research Institute, Mumbai

TATA Cancer Research 1. Improvement of quality of Institute life in Cancer patients (Study will be initiated shortly) 2.Screening of Herbal drugs for potential anti-Cancer activity (in the process of finalization) Dept. of Orthopedics, Asthi saushirya kilpauk Medical college (Osteoporosis)­ Pre-clinical Chennai studies completed. ANNA Peripheral Yakrit Vikar (Hepatitis ­ B) Hospital attached to preclinical studies completed kilpauk Medical college Chennai Women & Children Hospital, Egmore, Chennai Govt. Ayurvedic College & Hospital Nanded Rakta Pradar (Dysfunctional Uterine Bleeding)­ preclinical studies completed 1.Yavakshara ointment in piles ­ in progress 2.Yashtimadhu eye drops in dry eye syndrome -in progress 3.Anti microbial/wound healing action of selected herbs. - in progress Development of wound healing drugs for sports injuries - under process

6

CRI, Siddha, Chennai

7

CRI, Siddha, Chennai

8

CRI, Siddha, Chennai

9

CCRAS, Hqs.(Ph.D. Thesis guided by Director)

10

CCRAS Hqs

BRDE, Gwalior

Annexure-III SOME IMPORTANT ONGOING RESEARCH ACTIVITIES Nutraceutical Research · A study on effect of certain Ayurvedic Rasayana Food Supplements and Drink has been conducted at Antarctica Expeditions organized by National Centre for Antarctic and Ocean Research, Government of India and the results are encouraging in terms of immunomodulatory action, anti-oxidant effects besides improvement in physical and physiological parameters. The council is developing an herbal drink named "AYUSH PANAK", which is useful for indigestion, loss of appetite and other related digestive disorders. Evaluation of Iron content of the food prepared in the Iron vessels in comparison with other metal vessels and study of its efficacy in raising hemoglobin percentage shows encouraging result.

· ·

Cosmaceutical Research · The Council is developing a face pack as de-pigmentation agent to be used in melasma. The safety study of the drug is completed and it is proved to be clinically safe as regards to external application. The toxicity study of the drug is in progress. An anti crack cream is also developed by the Council and its safety and efficacy study is under process.

·

Biomedical instrumentation · Automization of the instruments used in Panchakarma therapy is in progress in collaboration with IIT, Delhi

Family Welfare Research · Clinical and Pharmacological Research studies carried out so far in the field of Family Welfare Research resulted in the development of "PIPPALYADI YOGA" as an Oral Contraceptive and "Neem Oil" as spermicidal agent. The toxicity study, Teratogenic study and Phase I study pf Pippalyadi Yoga has been completed and no toxicity, teratogenicity and adverse effect have been reported. A multicentric Phase II clinical trial is in progress at AIIMS, New Delhi, PGI, Chandigarh, K E M Hospital Mumbai and JIPMER, Pondicherry.

·

·

Reproductive and Child Health Care Programme · · The Council has developed two drugs i.e. Bal Rasayan and Ayush Ghutti for the general health of children. A feasibility study on mainstreaming of Indian System of Medicine into National RCH Programme at Primary Health Centre (PHC) level is being carried out in collaboration with ICMR.

Annexure-IV SL.NO 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 22. 23. 24. 25. 26. 27. 28. 29. 30. NEW CLINICAL PROGRAMME PROJECTION NAME OF THE DISEASE Rasayana for elderly persons Rajonivratti janya lakshana samucchaya (Menopausal syndrome) Hridroga (Chronic stable Angina) Mutrashmari (Urolithiasis) Madhumeha (Diabetes mellitus) Amavata (Rheumatoid arthritis) Vataja Panduroga (Sickle Cell Anemia) Vyanabala Vaishamya (Hypertension) Asthi kshaya (Osteoporosis) Animitta Raktapradara (Dysfunctional Uterine Bleeding) Kamala (Hepatitis-B, Hepatitis-A and Hepatitis-C) Ardhava Bhedaka (Migraine) Shushkakshipaka/Parishuskha Netra (Dry Eye Syndrome) Linganasa (Senile Immature Cataract) Abshisyanda (Allergic Conjunctivitis) Tamaka Swasa (Bronchial Asthma) Gambhir shira Rakta Skandha (Deep vein Thrombosis) Morbid cases of slipada (Filariasis) Vishama jwara (Malaria) Kampavata (Parkinsonism) Apasmara (Epilepsy) Chittodvega (Anxiety neurosis) Pakshaghata (Hemiplegia) Manas mandata (Mental Retardation in children) Mamsa Sosha (Muscular Dystrophy ­ Limb girdle type) Vyasana (Tobacco de-addiction) Bhagandara (Fistula ­ in ­ ano) Supportive therapy for the Improvement of Quality of life in Cancer patients Supportive therapy for the Improvement of Quality of life in HIV-AIDS patients

Annexure-V PATENTS - TECHNOLOGY DEVELOPMENT AND TRANSFER The treatment and technologies developed through the research are finally patented and commercialized. For patenting and commercialization of new formulations and technologies an MOU has been signed with National Research Development Corporation (NRDC), New Delhi. A - Number of patents obtained : 19 B - Patents filed : 12

A1) Patent Granted in India S.No. Name of the patent Patent Granted No AYUSH-64 - An anti-malarial preparation 152863 AYUSH-56 - An anti-epileptic preparation 141170 777 Oil - A medicated oil for Psoriasis 166740 Ksharsutra - A medicated thread for Ano- rectal 186243 diseases BAL RASAYAN - A herbo- mineral preparation for 196916 general resistance in children Ayush Ghutti "A herbo -mineral formulation" 193336 --process --Formulation A process for the production of a Lactonic glycoside 138350 from Nerium indicum Mill. (syn. N. odorum Sol.) A process for the production of an Extract useful in the 139868 treatment of Bronchial asthma from Mesua ferrea Linn. Seeds A process for the production of a Sodium Salt of a 140032 natural methyl chromone isolated from the pods of Cassia siamea A process for the isolation of a Pongaflavone from 140321 Pongamia pinnata (L.) Pierre (syn. P.glabra). A process for the isolation of 2.3.-a, a- 140367 Dimenthylchromen ­ 1-methoxy9-hydroxy-10y,ydemethylallyl pterocarpan, known as Gangetin, from the roots of Desmodium gangeticum A process for the production of a Benzofuran 139869 derivative from colic acid and catechol A process for the isolation of Tomatid-5-en-3b-ol from 140381

1. 2. 3. 4. 5. 6.

7. 8.

9.

10. 11.

12.

13.

14. 15.

16. 17.

18.

the leaves of Solanum trilobatum A process for the isolation of Methylangolensate and Deoxyandirobin from the bark of Soymida febrifuga A process for the production of a new triterpenoid glycoside named Entanin isolated from the seed kernals of Entada scandens Benth. A process for the isolation of Liriodenine, a 7-oxo aporphine from the heartwood of Aquilaria agallocha A process for the isolation of 2-Hydroxy-3 (3-methylbutenyl)- 1, 4-napthaquinone, known as Lapachol from the root of Steriospermum tetragonum A process for the preparatin of 9,13-Epoxy-6 bhydroxy-8a- Labdana-16,15: 19,2-diolactone known as Nepetaefolinol from the whole plant of Leonotis nepetaefolia Linn

140382 140384

145858 147936

140367

19. A process for the isolation of vincristine from rosea

Vinca 150019

20. A process for the preparation of vinblastine from Vinca 150024 rosea

A2) Patent Filed in India S. No.

1. A herbal preparation for combating stress borne 961/DEL/2004

Dt. 27.5.2004

Name of the patent

Patent Filed

syndrome in extreme cold conditions"

2. KVM Syrup

"A preparation for the treatment

of running and stuffy nose, productive or non 1313/DEL/2006 productive with or without fever and to a process for the preparation thereof"

3. AYUSH

Dt 31.5.2006

­SS

granules

"A process for

Dt 01.8.2008

preparation of an Ayurvedic herbal compound 1835/DEL/2008 preparation"

4. AYUSH LND Tablet "A process for preparation 1834/DEL/2008

of an Ayurvedic herbal compound preparation"

5. A

Dt 01.8.2008

Process for the Preparation of Novel 168/Cal/02

Composition from Swertia chirata Buch. Ham. dated 26.3.2002 (Gentianaceae) having Anti-carcinogenic

(cancer Preventive) and anti- Tumor (Cancer Therapeutic) Action

6. A Process for the Isolation of Amarogentin, 169/cal/02

7.

8.

9.

Novel Seco-Iridoid Glycoside Possessing Anticarcinogenic (Cancer Preventive) and AntiTumor (Cancer Therapeutic) Action A novel Anti-Cancer composition from Plant Source with Anti-carcinogenic (Cancer Preventive) and Anti- Tumor (Cancer Therapeutic) Action. compound Amarogentin, A novel Anti-Cancer A Seco- Iridoid Glycoside with AntiCarcinogenic (Cancer Preventive) and Antitumor (Cancer Therapeutic) Action. Nimbatiktam ­ for the management of Psoriasis (Kitibha).

dated 26.3.2002 167/Cal/02 dated 26.3.2002. 166/Cal/2002 dated 26.3.2002. 545/DEL/84

B) Patent Filed and Granted in abroad: S.No. 1. Name of the patent Patent Granted No A process for preparation of an Ayurvedic German patent no. formulation for treatment of Leukemia" 69905773,6-08

Technology Developed/ transferred (Licensee fee/Non-exclusive) in the last 5 years: A) Technology Developed in the last five year 1) An herbal preparation for combating stress borne syndrome in extreme cold conditions. 2) KVM Syrup "A preparation for the treatment of running and stuffy nose, productive or non productive with or without fever and to a process for the preparation thereof'' 3) AYUSH-AG Tablet "A process for preparation of product for Ante natal care" 4) AYUSH ­SS granules "A process for preparation of product for post natal care" 5) AYUSH PG Tablet "A process for preparation of product for Ante natal care" 6) AYUSH LND Tablet "A process for preparation of an Ayurvedic herbo mineral compound preparation" 7) AYUSH BALRAKSHAK LEHYAM "A process for preparation of product for paediatric care. 8) AYUSH PK AVALEHA "A process for preparation of product for post natal care" 9) AYUSH UT OINTMENT "A process for preparation of an Ayurvedic herbal compound preparation" 10) BAL RASAYAN ­ A process for herbomineral preparation for general resistance in children. (Patent No.196916 dated) 11) AYUSH GHUTTI - A process for herbo -mineral formulation for children.

B) Technology Transferred in the last five year

1) AYUSH-64 - An anti-malarial preparation (Patent No. 152863 dated 28.7.1980). 2) AYUSH-56 - An anti-epileptic preparation (Patent No. 141170 dated 28.7.1976). 3) 777 Oil A medicated oil for Psoriasis (Patent No. 166740 dated 11.9.1987) 4) BAL RASAYAN - A herbomineral preparation for general resistance in children. 5) (PatentNo.196916dated) AYUSH GHUTTI - A herbo -mineral formulation

6) AYUSH ­SS granules "A process for preparation of product for post 7) natal care" AYUSH-AG Tablet "A process for preparation of product for Ante natal care" 8) AYUSH PG Tablet "A process for preparation of product for Ante natal care" 9) AYUSH KVM Syrup " A process for preparation of product for Pediatric care.AYUSH BALRAKSHAK LEHYAM "A process for preparation of 10) product for pediatric care. "A process for preparation of product for post 11) AYUSH PK AVALEHA natal care"

Annexure-VI RATE LIST FOR DIFFERENT TYPES OF SERVICE CHARGES GENERAL INSTRUCTIONS 1. Employees of Council and their dependents are exempted from all charges. 2. For Senior Citizens (documents to be verified/at the discretion of In-charge). a) Registration ­ free. b) 30% of the rate for all other services will be charged. 3. Research Programme cases of Council ­ Exempted from all charges. 4. Patients belong to BPL (Below Poverty Line) (documents to be verified at the discretion of In-charge)- exempted from all charges. 5. Botanical and Chemical analysis for students coming for study purpose ­ 50% discount may be given. 6. The Institute may circulate drug testing Rate List to pharmaceuticals/industries. 7. The Institute may issue certificate regarding standardization and testing report (Report is not valid for legal purpose). 8. Printing of Receipt Books may be done at the Institute level subject to the condition that the Sr. Nos. of the Receipt Books will be maintained. 9. Any other resources if identified by any institute, the concerned In-charge may fix the rate and intimate the Council.

CENTRAL COUNCIL FOR RESEARCH IN AYURVEDA AND SIDDHA Approved rate list for different types of service charges S.No. AREA OF RESOURCES Charges (Rs.) 1 IN PATIENT DEPARTMENT (IPD) Admission Fee with discharge certificate (for general cases) 10/Admission Fee with discharge certificate (for research Free cases) Diet & Medicine per day (general cases) 25/Diet & Medicine per day (research cases) Free Special ward (including diet and medicine) (per day) 150/Special ward (nurse/attendant from Pvt. Agency on As per local rate Call) (per day) 3

st

KSHAR SUTRA THERAPY

200/1 Threading Subsequent Threading (per sitting) 50/Piles tie 200/4 PANCHAKARMA THERAPY ( per day and exclusive of materials) Abhyanga & Swedana Shali Shasti Pinda Sweda Patra Potalam Basti Snehadhara Shirodhara Shirobasti Katibasti Vamana Nasya Aschyotana/Seka/Bidalaka/Anjana (each) Nadisweda Baluka Sweda Jalaukavacharan Akshitarpana Eye Exercise Eye Testing Lekhana Infra Red Therapy Uttar Basti 5 Treatment with one electric modality (US, SWD, Traction etc.) 75/150/75/50/100/75/50/25/50/25/10/25/10/25/30/20/20/10/20/30/PHISIOTHERAPY (per sitting) 15/-

Treatment with two electrical modalities One electrical modality with exercise Exercise for Hemiplegia, Paraplegia 6 Hydrocele Hernia Appendicitis M.T.P. Tubectomy 7 Pathology TLC DLC ESR Hb% CT BT AFB MP/MF URINE (Routine, Microscopic) STOOL (Ova, Cyst) STOOL (Occult Blood) SEMEN Analysis Pregnancy Test (including kit) Bio-Chemistry Sugar (Fasting/PP/Random each) Blood Urea S Creatinine S Uric Acid Total Cholesterol LDL Cholesterol HDL Cholesterol VLDL Cholesterol Triglycerides S. Proteins S. Albumin & Globulin Total Bilirubin SGOT SGPT

25/25/50/MINOR SURGERY (after clearance from ethical committee) 1000/- + Anaesthesia charges 2000/- + Anaesthesia charges 3000/- + Anaesthesia charges 500/- + Anaesthesia charges Free LAB. INVESTIGATIONS 5/5/5/5/5/5/20/10/10/10/10/25/20/10/10/10/10/15/10/10/10/10/10/15/15/15/15/-

S. Alkaline Phosphatase S. Acid Phosphatase Sodium + Potassium Calcium Phosphorus Amylase CPK Immunology/Serology RA Factor (qualitative) RA Factor (quantitative) CRP ASO titre Blood Group and Rh type VDRL Widal Test Mantoux Test Serum TSH Serum T 3 Serum T 4 Serum TSH, T3 & T4 Complete Haemogram 8 Per view ­ Plain X-Ray Fistulogram (excluding dye) 9. 10 General Cases Research Cases 11

10/10/15/10/10/10/15/20/60/35/25/15/25/15/10/50/50/50/150/50/X-RAY 20/50/E.C.G. 30/SICKNESS AND FITNESS CERTIFICATE 10/Free AMBULANCE IN As per local rate EMERGENCY (called/hired) LIBRARY CHARGES 500/-

12 Membership (per annum, non-refundable) (students/research scholars-50% discount admissible)

Membership (up to 1 month, non-refundable) (students/research scholars-50% discount admissible) Membership (less than a week in deserving cases) Security Deposit (refundable) (no deposit from Govt. Organizations) Xerox per page (reference books)

50/Free 2000/1/-

13 Nimbidin Capsule (per capsule) Lajjalu Keram (per 100 ml.) Aragwadha Tailam (per 100 ml.) Chakramardha Keram (per 100 ml.) 14 Nature of test

0

SPECIFIC MEDICINE 2/20/20/20/TESTING OF AYURVEDIC CRUDE DRUGS AND FORMULATIONS 50/100/200/200/200/150/200/100/300/1500/500/75/75/50/75/100/200/200/150/75/100/200/200/200/200/200/200/500/200/200/200/-

Loss on drying at 105 C Refractive index Acid value Saponification value Iodine value Fat content/oil content Peroxide value for ghrita and taila Rancidity test TLC (with photographs) HPTLC GLC (single component) Ash Acid insoluble ash pH Specific gravity Total solids Alcohol content Reducing sugar and Total sugar (each) Volatile matter Water soluble extractive Alcohol soluble extractive Assay for Iron Assay for Calcium Assay for Potassium Assay for Sodium Assay for Tin Assay for Silver Assay for Gold Assay for Lead Assay for Copper Assay for Arsenic

Assay for Zinc Assay for Aluminium Assay for Mercury Resin content Disintegration test Identification of raw drugs by Microscopy (by section cutting of single drug) Identification of raw drugs by Powder Microscopy Standardization of single plant drug as per APC format Standardization of single plant drug as per WHO guidelines 15 forwarding charges extra)

200/200/200/150/50/1000/500/5000/7000/CRUDE DRUGS (for the institutions other than CCRAS Units) (Packing &

Name of the Medicinal plants Agnimantha ­ Clerodendrum phlomidis l.f. ­ Root Arlu ­ syonak ­ Ailanthus excelsa Roxb. ­ .Bark Arjun ­ Terminalia arjuna Roxb. - Bark Ashok ­ Saraca asoca (Roxb.) De Wilde - Bark Amra ­ Mangifera indica Linn. ­ Seed (kernel) Amalaki ­ Emblica officinalis Gaertn.- Fruit Aragwadha ­ Cassia fistula Linn. ­ Fruit-pulp (per pod) Atibala ­ Abutilon indicum (Linn.) Sweef ­ Whole plant Avartani ­ Helicterious isora Linn. - Fruit Bilva ­ Aegle marmelos Corr. ­ Leaf (fresh) Bilva ­ Aegle marmelos Corr. ­ Fruit unripe intact Brahmi ­ Bacopa monieri (Linn.) Pennel ­ Whole plant (fresh) Brahmi ­ Bacopa monieri (Linn.) Pennel ­ Whole plant (dried) Bhumyamalki ­ Phyllanthus fraternus/amarus Schum & Thom ­ Whole plant Chakramard ­ Cassia tora Linn. - Seed Dronpushpi ­ Leucas cephalotus Spreng. ­ Whole plant Guduchi ­ Tinospora cordifolia Willd. ­ Stem (dried) Guduchi ­ Tinospora cordifolia Willd. ­ Stem (fresh) Isabgol ­ Plantago ovata Forsk. - Seed Kaidarya ­ Murraya koenigii (Linn.) Spreng.­ Leaf (fresh) Karanja ­ Pongamia pinnata Pierre - Seed Lajjalu ­ Mimosa pudica Linn. ­ Whole plant Masparni ­ Phaseolus trilobus (Linn.) Schreb. ­ Whole plant Nimba ­ Azadirachta indica A. Juss. ­ Seed

25/40/20/60/40/50/3/40/25/30/15/30/85/30/20/40/25/15/35/40/40/125/35/40/-

Sirish ­ Albizia lebbeck Benth. ­ Bark (dried) Satavari ­ Asparagus racemosus Willd. ­ Root (fresh) Sadabahar ­ Vinca rosea Linn. - Leaf 16 MEDICINAL PLANTS/SEEDLINGS/SAPLINGS Name of Plant Amalaki ­ Emblica officinalis Gaertn.- Per seedling Anantmula ­ Hemidesmus indicus R. Br. ­Per plant Anantmula ­ Tylophora indica (Burm. f.) Merr.-Per plant Ayapan ­ Eupatorium ayapana Vent. -Per sapling Aparajita ­ Clitoria ternatea Linn.-Per sapling Apamarg ­ Achyranthes aspera Linn.-Per sapling Arka (Rakta) ­ Calotropis procera Br.-Per sapling Arka (Sweta) ­ Calotropis gigantea Br. -Per sapling Ashwattha ­ Ficus religiosa Linn. ­ Per plant Amragandhi Haridra ­ Curcuma amada Roxb. -Per sapling Ardrak ­ Zingiber officinale Rosc. -Per sapling Arishtaka ­ Sapindus trifolius Linn. -Per sapling Aragvadha ­ Cassia fistula Linn. ­Per sapling Arjuna ­ Terminalia arjuna. Roxb.-Per plant Ashoka ­ Saraca asoca (Roxb.) De Wilde ­Per plant Aswagandha ­ Withania somnifera Dunal-Per two saplings Brihati ­ Solanum indicum Linn. ­ Per seedling Bilwa ­ Aegle marmelos Corr. -Per sapling Bibhitak ­ Terminalia bellerica Roxb. ­ Per plant Bakuchi ­ Psoralea corylifolia Linn. - Per plant Bharangibheda ­ Clerodendrum indicum (L.) Kuntz. - Per sapling Bala ­ Sida cordifolia Linn. ­ Per seedling Bakula ­ Mimusops elengi Linn. ­ Per seedling Bhallatak ­ Semecarpus anacardium Linn. ­ Per plant Bhringaraj ­ Eclipta alba Hassk. ­ Per seedling Bhumikushmanda ­ Ipomoea paniculata R. Br. ­ Per seedling Brahmi ­ Bacopa monnieri (Linn.) Pennel ­ Per five plants Bhumyamalaki ­ Phyllanthus amarus Schum & Thon ­ Per five plants Bhustrina ­ Cymbopogon citratus Stapf ­ Per seedling Barbari ­ Ocimum basilicum Linn. ­ Per seedling Chandan ­ Santalum album Linn. ­ Per plant Champak ­ Michelia champaca Linn. ­ Per plant Chakramarda ­ Cassia tora Linn. ­ Per seedling Chitraka (Rakta) ­ Plumbago rosea Linn. ­ Per two plants

25/35/80/-

7/5/5/5/5/5/4/5/5/5/10/5/5/5/20/5/5/5/5/5/5/5/5/10/5/5/5/5/5/5/5/10/5/5/-

Chitraka ­ Plumbago zeylanica Linn. ­ Per plant Dhatura ­ Datura metel Linn. ­ Per sapling Erand Karkati ­ Carica papaya Linn. ­ Per Plant Ghrita Kumari ­ Aloe vera Linn. ­ Per five plants Guduchi ­ Tinospora cordifolia Willd. ­ Per three plants Guggulu ­ Commiphora wightii (Arn.) Bhand. ­ Per plant Gunja ­ Abrus precatorius Linn. ­ Per plant Haritaki ­ Terminalia chebula Retz. ­ Per plant Haridra ­ Curcuma longa Linn. ­ Per plant Jambu ­ Syzygium cumini Skeels ­ Per plant Japa ­ Hibiscus rosasinensis Linn. ­ Per three plants Kapikachchhu ­ Mucuna pruriens Baker. -Per sapling Kakmachi ­ Solanum nigrum Linn. ­ Per three plants Kalmegha ­ Andrographis paniculata Willd. ­ Per five plants Karmarda ­ Carissa carandas Linn. ­ Per plant Kapur Tulsi ­ Ocimum kilimandscharicum Guerke ­ Per two plants Karpura ­ Cinnamomum camphora (L.) Nees & Eberm. ­ Per two plants Kutaj ­ Holarrhena antidysenterica Wall. ­ Per two seedlings Kokilaksha ­ Astercantha longifolia Nees ­ Per sapling Karanj ­ Pongamia pinnata Pierre ­ Per plant Surabhinimba ­ Murraya koenigii Spreng. ­ Per plant Lajjalu ­ Mimosa pudica Linn. ­ Per plant Lata Kasturi ­ Hibiscus abelmoschus Linn. ­ Per seedling Langli ­ Gloriosa superba Linn. ­ Per seedling Lata Karanja ­ Caesalpinia crista Linn. ­ Per plant Madayantika ­ Lawsonia inermis Linn. ­ Per sapling Mudgaparni ­ Phaseolus trilobus Ait. ­ Per sapling Mandukaparni ­ Centella asiatica (L.) Urban ­ Per plant Mahabala ­ Sida rhombifolia Linn. ­ Per two seedlings Maricha ­ Piper nigrum Linn. ­ Per seedling Mesasringi ­ Gymnema sylvestre R. Br. ­ Per sapling Nagkesar ­ Mesua ferrea Linn. ­ Per sapling Nirgundi ­ Vitex nigundo Linn. ­ Per sapling Nimba ­ Azadiracta indica A. Juss. ­ Per three plants Nilini ­ Indigofera tinctoria Linn. ­ Per sapling Pasan bheda ­ Bergenia ligulata Wall. Engl. ­ Per plant Pipermint ­ Mentha piperita Linn. ­ Per sapling Putiha ­ Mentha arvensis Linn. ­ Per sapling Parnabija ­ Bryophyllum pinnatum (Linn) Kurz. ­ Per two saplings

5/5/5/5/5/20/5/5/10/5/5/5/5/10/5/5/5/5/5/10/5/5/5/10/5/5/5/5/5/5/10/5/5/5/5/5/5/5/5/-

Pippali ­ Piper longum Linn. ­ Per sapling Punarnava ­ Boerhavia diffusa Linn. ­ Per sapling Prisniparni ­ Uraria picta Desv. ­ Per sapling Parijata ­ Nyctanthes arbortistis Linn. ­ Per plant Peet Karveer ­ Thevetia peruviana (Pers.) Schum ­ Per two seedlings Rohisa ­ Cymbopogon martini (Roxb.) Wats. ­ Per sapling Sadabahar ­ Cathranthus roseus G. Don ­ Per two saplings Sinduri ­ Bixa orellana Linn. ­ Per two plants Swarnapatri ­ Cassia angustifolia vahl. ­ Per plant Salparni ­ Desmodium gangeticum DC. ­ Per plant Sweta Musli ­ Chlorophytum arundinaceum Baker ­ Per plant Sarpagandha ­ Rauwolfia serpentina Benth. ex Kurz. ­ Per sapling Shankhapuspi ­ Convolvulus pluricaulis Linn. ­ Per sapling Shatavari ­ Asparagus racemosus Willd. ­ Per plant Shigru ­ Moringa oleifera Lam. ­ Per plant Shallaki ­ Boswellia serrata (Roxb.) Schutz ­ Per plant Shati ­ Hedychium spicatum Ham. ex. Sm. ­ Per seedling Tulsi ­ Ocimum sanctum Linn. ­ Per two plants Ulatkambal ­ Abroma augusta Linn. ­ Per sapling Vacha ­ Acorus calamus Linn. - Per sapling Vrischikali ­ Tragia involucrata Linn. ­ Per seedling Vyagranakhi ­ Martynia annua Linn. ­ Per seedling Vacha ­ Acorus calamus Linn. - Per sapling Vasa ­ Adhatoda vasica Nees ­ Per sapling Yavani ­ Trachyspermum ammi Linn. ­ Per seedling - - Artemisia annua Linn. ­ Per sapling Agnimantha ­ Clerodendum multiphlorum Agalocha ­ Commiphora agallocha Chincha ­ Tamarindus indica Chirabieva ­ Holoptelea integrifolia Dhataki ­ Woodfordia fruticosa Dikemali ­ Gardenia resinifera Jyotishmati ­ Celastrus paniculatus Jangli-badam ­ Terminalia catappa Kandavel, Asthisamhari ­ Cissus quardrangularis Karanja ­Pongamia pinnata Kovidara ­ Bauhinia purpurea Kanchan vel ­ Bauhinia vahlii Lajjalu ­ Mimosa pudica

5/5/5/5/5/5/5/5/5/5/5/10/5/5/5/10/5/5/5/5/4/5/5/5/5/5/10/20/10/10/20/15/10/10/10/5/5/15/10/-

Madhavi ­ Hiptage benghalensis Madhuka ­ Madhuca longifolia var, latifolia Nakli-sarpagabadga ­ Rauvolfia tetraphylla Panasa ­ Artocarpus heterophylus Parna-ajwan ­ Coleus amboinicus Palasha ­ Butea monosperma Paribhadra ­ Erythrina variegata Passion fruit ­ Passiflora eduls Ramphala ­ Anona reticulate Rohitaka ­ Aphanamixis polystachya Samudra shaka ­ Amureia nervosa Sher ­ Sarcostemma acidum Satab ­ Ruta graveolens Sarpagandha ­ Rauvolfia serpentina Shyonaka ­ Oroxylum indicum Saharchara ­ Barleria prionitis Shveta-shalmali ­ Ceiba pentendra Vata ­ Ficus benghalensis - Caesalphinia sappan 17 EXTRACT OF PLANT MATERIAL Extract from powder plant material (per kg.) (plant material to be provided by party) Extract from plant material (per kg.) (plant material and solvent provided by party)

10/10/10/20/10/10/5/20/10/10/5/10/20/20/20/10/10/10/20/1000/300/-

Separation of the extract in to 4 different fractions by column chromatography (per 10 gm.) (extract & solvent supplied by party) Separation of the extract in to 4 different fractions by column 1000/chromatography (per 10 gm.) (extract supplied by party) 500/Organic qualitative test (per extract) 18. Acute toxicity (time required ­ 6 days) Sub-Acute toxicity (inclusive of Histopathological charges and determination of biochemical parameters) (time required ­ 50 days) Chronic toxicity (inclusive of Histopathological charges and determination of biochemical parameters) (time required ­ 120 days) 19. PHARMACOLOGICAL STUDIES Anti-inflammatory activity (carragenin induced paw odema) (time required ­ 3 days) 2,500/100/TOXICITY STUDY 4,950/33,000/37,400/-

Anti-inflammatory activity (cotton pellet granuloma) (time required ­ 15 days) Hepatoprotective activity (time required ­ 20 days) Antifertility activity (Anti-ovulatory activity) (time required ­ 20 days) Antifertility activity (Anti-implantation activity) (time required ­ 45 days) Antifertility activity (Abortifacient activity) (time required ­ 45 days) 20 IDENTIFICATION OF SPECIMEN

5,500/9.500/2,500/4,000/4,000/-

Live plants and herbarium specimen (Per plant/specimen) 20/Supply of coloured photographs of medicinal plants used in 50/Ayurveda (postcard size copy along with label depicting Ayurvedic name, scientific name and parts used) per photograph & postal charges extra 21 SHORT TRAINING COURSES (excluding boarding & lodging) Training in local survey and collection of medicinal plants/folk claims (Per head for three days, minimum batch of 10 persons) Training in local survey and collection of medicinal plants/folk claims (Per head for three days, minimum batch of < 5 persons) Training in tissue culture (Per head for 5 days) Training in drug standardization (Per head for 5 days) Training in pharmacognosy (Per head for 5 days) 22. Parameter/Analysis Flurescence analysis of extracts ( per extract) Foaming index Inorganic qualitative test ( per element) Successive extraction with petroleum ether, Acetone and Ethyl alcohol (per 50 g.) (Plant material to be provided by the party) Swelling index 500/750/1000/1500/200/50/50/20/300/50/-

23. Visit to the medicinal plant garden ­ Proposed rates for foreign visitor and co-operate visitor (per head) Rs.50/-

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