Read Type of bioreactor and design text version

Type of bioreactor and design

Polson Mahakhan; MIC431 Bioreactors

1

· · · () · ·

Polson Mahakhan; MIC431 Bioreactors 2

reactor design

· Weizman 1941-1918

­ Clostridium acetobutylicum -> acetone ­ anaerobic

· 1930-1940 Compressed yeast

­ Aerobic

· 1943 Penicillin -> submerged culture

Polson Mahakhan; MIC431 Bioreactors

3

· · , · · pH · · ·

· ·

· · · , ·

4

Polson Mahakhan; MIC431 Bioreactors

Polson Mahakhan; MIC431 Bioreactors

5

·

­ ; ­ stainless stell ­ ­ phenolic epoxy ­ ­

· , , , ()

Polson Mahakhan; MIC431 Bioreactors 6

Polson Mahakhan; MIC431 Bioreactors

7

· Laboratory scale fermenter · Pilot-plant scale fermenter · Factory scale fermenter

­ 20,000, 50,000, 500,000, 2,500,000 L

Polson Mahakhan; MIC431 Bioreactors 8

­ 1-20 L, working volume ½-15 L ­ 40-200 L -> 1000 L

Polson Mahakhan; MIC431 Bioreactors

9

· (aeration) · (agitation) · (temperature cont.) · - (pH cont.) · (oxygent cont.) · (antifoam control)

Polson Mahakhan; MIC431 Bioreactors 10

Polson Mahakhan; MIC431 Bioreactors

11

Polson Mahakhan; MIC431 Bioreactors

12

Polson Mahakhan; MIC431 Bioreactors

13

Polson Mahakhan; MIC431 Bioreactors

14

Polson Mahakhan; MIC431 Bioreactors

15

· Packed tower · Tower fermenter · Waldhof-type fermenter · Acetator & cavitator · Cyclone column · Cylindro-conical vessel · Air-lift fermenter · Deep-jet fermenter · Rotating disc fermenter

Polson Mahakhan; MIC431 Bioreactors 16

Packed tower · ·

· , · · Generator · , · , ,

Polson Mahakhan; MIC431 Bioreactors 17

­ , , , , polystyrene

Polson Mahakhan; MIC431 Bioreactors

18

Tower fermenter

() · tubular section 6:1 or total 10:1 · · batch continuous · · Besik 1973

Polson Mahakhan; MIC431 Bioreactors 19

Tower fermenter

Polson Mahakhan; MIC431 Bioreactors

20

Waldhof-type fermenter

· yeast sulphite waste liqour · rotating pin-wheel ·

­ , ­

Polson Mahakhan; MIC431 Bioreactors

21

Waldhof-type fermenter

Rotating pin-wheel

Polson Mahakhan; MIC431 Bioreactors 22

Acetator

· Frings generator · Heindrich Frings · Acetobacter · · self-priming aerator ·

Polson Mahakhan; MIC431 Bioreactors 23

Frings generator Mahakhan; MIC431 Polson

Bioreactors

Self-priming aerator

24

Polson Mahakhan; MIC431 Bioreactors

25

Cavitator

· · ·

· acetator

Polson Mahakhan; MIC431 Bioreactors 26

Cyclone column

· · · ·

· ·

Polson Mahakhan; MIC431 Bioreactors 27

Cylindro-conical vessel

· Nathan 1930 · 1960 · · 22-25 m 6 m 450,000 · 40-48 h, · ·

Polson Mahakhan; MIC431 Bioreactors 28

Cylindroconical vessel

Polson Mahakhan; MIC431 Bioreactors 29

Polson Mahakhan; MIC431 Bioreactors

30

Air-lift fermenter

· single cell protein

methanol · · Air-lift 45 m

­ Outer loop < inner loop ­

Polson Mahakhan; MIC431 Bioreactors 31

Air-lift fermenter

Outer loop

Polson Mahakhan; MIC431 Bioreactors

Inner loop

32

Polson Mahakhan; MIC431 Bioreactors

33

Deep-jet fermenter

· · air entrainer

Polson Mahakhan; MIC431 Bioreactors

34

Rotating disc fermenter

· · disc · Anderson & Blain 1980

­ Polypropylene disc, 40 L ­ Aspergillus, Rhizopus, Mucor, ­ citric acid A. niger, 80g/l

Polson Mahakhan; MIC431 Bioreactors 35

Penicillium

Polson Mahakhan; MIC431 Bioreactors

36

· · , ·

Polson Mahakhan; MIC431 Bioreactors

37

Information

Type of bioreactor and design

37 pages

Report File (DMCA)

Our content is added by our users. We aim to remove reported files within 1 working day. Please use this link to notify us:

Report this file as copyright or inappropriate

946757