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CHEM 4010 - Macromolecular Systems 1 Principles of large molecules and polymeric materials: physical states, morphology, strength, processing; synthesis and biosynthesis; characterization. CHEM 4552 ­ Instrumental Characterization of Organic Compounds Molecular analysis, NMR, IR and UV spectroscopy, mass spectroscopy, chromatography, thermal analysis and combination of techniques CHEM 4553 ­ Instrumental Characterization of Organic Compounds-Lab Applications of molecular analysis. CHEM 4561- Intermediate Physical-Organic Chemistry Selected topics in kinetics, reaction mechanisms , applications of quantum mechanics to organic chemistry, and related topics in physical organic chemistry CHEM 4562- Intermediate Organic Chemistry Selected topics in synthesis, natural products chemistry, stereochemistry, reaction mechanisms and related topics in structural and synthetic organic chemistry CHEM 4570 ­ Advanced General Inorganic Chemistry Principles in advanced inorganic chemistry; modern interpretations CHEM 4581 ­ Introduction to Mathematical Chemistry Mathematical methods of chemistry, with application to selected chemical problems CHEM 4594 ­ Introduction to Quantum Chemistry Basic ideas of quantum mechanics; application to atomic and molecular structure

CHEM 7750- Analytical Section 1: Analytical Spectroscopy This course covers the fundamentals and applications of analytical spectroscopy including ultraviolet and visible absorption spectroscopy, fluorescence spectroscopy, atomic emission and absorption spectroscopy, infrared and raman spectroscopy, nuclear magnetic resonance spectroscopy and mass spectrometry. In addition, we will also cover lasers, optics, and optical system design. The course will be a combination of traditional lecture and student presentations. There will be periodic homework and other assignments, a midterm exam and a final exam. Section 2: Fluorescence The focus of this course is on analytical applications of fluorescence spectroscopy. As a graduate course, some perquisites are assumed. For this course, the prerequisites are primarily instrumental analyses and a solid background in physical chemistry. It would be beneficial, but not necessary, to have some background in photophysics. Preparation before class is essential; All assigned reading and homework should be completed promptly-not the night before an examination.

Revised: June 3, 2010

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CHEMISTRY GRADUATE DEPARTMENT FALL 2010 COURSE DESCRIPTIONS Section 3: Bioanalysis Purpose: Provide to the student information on the basic bioanalytical strategies used to perform molecular analyses. The analyses discussed will be focused on the biopolymers, such as nucleic acids (DNA and RNA) and proteins. There will be 3 general sections to this class: (1) Introduction to biopolymer structure; (2) Macro-scale techniques for elucidating molecular structure; (3) Micro- and nano-scale techniques for analyzing molecular structure. Specific topical areas that will be covered include PCR technologies, micro-scale bioseparations (multi-dimensional as well), DNA/protein microarrays, DNA sequencing and genotyping and immunoassays. Examples using the technologies introduced to the student will come from such areas as DNA forensics, molecular diagnostics and proteomics. CHEM 7770- Symmetry & Structure This is an introductory course suitable for new graduate students and those who have not taken our Inorganic (4570) or Organometallic (4571) courses. The course will start by covering symmetry and group theory with chemical applications towards the assignment of metal carbonyl IR and Raman spectra, selection rules for electronic transitions, and symmetry assignments of molecular orbitals (MO's). Various methods for performing MO calculations will be covered with emphasis on the Gaussian 09 program. Focus will be placed on the qualitative aspects of interpreting results from these calculations and in getting "chemistry" from the MO calculations. Electronic effects on chemical bonding and molecular structure will be explored, especially for transition metal complexes. Experimental methods for probing the electronic structure of molecules will also be discussed (photoelectron & optical spectroscopy, X-ray electron density maps, etc.) Students will have hands on experience with the Gaussian 09 and GaussView 5 programs and in interpreting results from their own calculations. Although the course will center on transition metal inorganic and organometallic complexes, some organic examples will be covered as well. The Cambridge Crystallographic Database software package will be used to illustrate unusual bonding and structural effects. Aspects of molecular modeling and conformational searching to find the optimum structure of molecules will be discussed. Text Book: Chemical applications of Group Theory by F. Albert Cotton, 3rd Ed.; plus examples from the literature. Detailed lecture notes for the symmetry and group theory portion of the course. CHEM 7800 ­ SEMINAR May be taken 6 times for credit; All graduates are expected to participate in report and discussion groups in field of chemistry of their particular interest. CHEM 7901 - Speak Macromolecules Multidisciplinary seminar that explores current research concerning macromolecules

Revised: June 3, 2010

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