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Division of Neurosurgery


Number of Faculty Number of Fellows Clinical Fellows Research Fellows Number of Other Students (full and part-time) Number of Support Personnel Number of Peer Reviewed Publications Patient Encounters Outpatient Inpatient 3 1 1 10 13 8 2,367 268


Kerry R. Crone, MD, Professor of Neurosurgery and Pediatrics, Director of Clinical Affairs and Graduate Education in Pediatric Neurosurgery; Director, Pediatric Neurosurgery Karin S. Bierbrauer, MD, Associate Professor Francesco T. Mangano, DO, Assistant Professor


The Pediatric Neurosurgery Division at Cincinnati Children's Hospital Medical Center is the largest and most comprehensive pediatric neurosurgery program in the region. Working closely with referring physicians and other medical and surgical specialties, the Pediatric Neurosurgery Division provides comprehensive care to patients and their families. The division's principal focus continues to be high quality delivery of expert surgical care for all phases of pediatric oncologic, developmental, functional, traumatic and vascular neurosurgical disorders. The division provides inpatient care, timely K. Bierbrauer, K. Crone, F. Mangano outpatient consultations and internet-directed inquiries. The Neurosurgery Division is comprised of three pediatric neurosurgeons: Kerry Crone, MD, Karin Bierbrauer, MD, and Francesco Mangano, DO. Their support staff includes highly knowledgeable registered nurses, nurse practitioners, physician assistants, residents and fellows. A dedicated 40-bed neuroscience unit provides unparalleled pre- and postoperative care for infants, children, teenagers and young adults. The Minimally Invasive Neurosurgery Division (MIND) is the result of years of ground-breaking research conducted by Dr. Kerry Crone and colleagues from around the world as they explored the use of an endoscope to treat a variety of neurosurgical disorders that at the time required doing "major" surgery. Thanks to their efforts, some procedures can now be accomplished with minimal blood loss, pain and scarring. Additionally, Dr. Crone pioneered the use of Stereotactic Minimal Access Resection Techniques (SMART) to remove deep-seated tumors that were previously thought to be inoperable. The new Cincinnati Children's neurosurgical operating suite, which opened in November 2006, is the only dedicated pediatric operating suite in the world to contain a full-sized MRI scanner. This intraoperative MRI in combination with an integrated neurosurgical microscope and stereotactic guidance system make this suite one of the most technically sophisticated operating rooms for children in the world.


Kerry R. Crone, MD, is the Director of Pediatric Neurosurgery at the Medical Center, Director of Clinical Affairs and Graduate Education in Pediatric Neurosurgery and Associate Professor of Clinical Neurosurgery and Pediatrics at the University of Cincinnati. A graduate of the University of Cincinnati College of Medicine in 1978, Dr. Crone completed his

2006­07 Annual Report Cincinnati Children's Research Foundation Page 241

internship in general surgery and residency in neurosurgery at the North Carolina Baptist Hospital, Bowman Gray School of Medicine, in Winston-Salem, NC. Dr. Crone was a clinical fellow in pediatric neurosurgery at the Hospital for Sick Children in Toronto, and a clinical scholar in neurosurgery at Cincinnati Children's. He was awarded certification by both the American Board of Neurological Surgery and the American Board of Pediatric Neurological Surgery. Through his clinical research, lectures and numerous professional publications Dr. Crone has earned an international reputation for excellence in pediatric neurosurgery and is recognized as a world leader in the development of endoscopic neurosurgery. Over the years Dr. Crone has served on a multitude of committees and boards at Cincinnati Children's as well as community based organizations which are associated with the Medical Center. His special interests include endoscopic management of complex hydrocephalus, SMART surgery for resection of brain tumors, surgical management of Chiari Malformation, and cranial reconstructive surgery for craniosynostosis. Karin S. Bierbrauer, MD is an Associate Professor of Pediatric Neurosurgery at the University of Cincinnati College of Medicine. Dr. Bierbrauer received her neurosurgical training at Emory University Hospital in Atlanta, Georgia and then went on to complete a fellowship in pediatric neurosurgery at Children's Memorial Hospital in Chicago in 1991. Dr. Bierbrauer's special areas of interest include spina bifida and all other types of spinal dysraphism (tethering of the spinal cord) and the care and management of neurosurgical diseases in the perinatal period, including hydrocephalus. She is a member of the Fetal Care Center of Cincinnati's team of subspecialists and will direct the neurosurgical evaluation and treatment of children enrolled in the comprehensive Myelomeningocele/Spina Bifida Clinic at Cincinnati Children's Hospital Medical Center. Dr. Bierbrauer was recently awarded an NIH grant involving hypothermic therapy for head trauma patients. Francesco T. Mangano, DO, is a faculty member of Pediatric Neurosurgery at the Medical Center and Assistant Professor of Clinical Neurosurgery and Pediatrics at the University of Cincinnati. A graduate of the Philadelphia College of Osteopathic Medicine, Dr. Mangano completed his residency in neurosurgery at Long Island Jewish Medical Center, the New York College of Osteopathic Medicine, in New Hyde Park, NY. Dr Mangano was a clinical fellow in pediatric neurosurgery at the St. Louis Children's Hospital in St. Louis, MO. He is a member of the American College of Osteopathic Surgeons, Neurological Surgery Section, and the Ohio Osteopathic Association. His special interests include complex spinal surgery, epilepsy surgery, cerebrovascular surgery, craniofacial surgery, neuro-oncology, and neuroendoscopy.


Nicholas Levine, MD Michael Petr, MD Samir Parikh, MD Bradford Curt, MD Andrew Grande, MD Ellen Air, MD Marcella Koch, MD Ondrej Choutka, MD Dean Hertzler, MD Andrew Losiniecki, MD Rachana Tyagi, MD PGY 6 PGY 6 PGY 5 PGY 4 PGY 4 PGY 3 PGY 3 PGY 2 PGY 2 PGY 2 Fellow University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati University of Cincinnati CCHMC


Levine NB, Collins J, Franz DN, Crone KR. Gradual formation of an operative corridor by balloon dilation for resection of subependymal giant cell astrocytomas in children with tuberous sclerosis: specialized minimal access technique of balloon dilation. Minim Invasive Neurosurg 2006;49(5):317-20. Tanaka T, Ling BC, Rubinstein JH, Crone KR. Rubinstein-Taybi syndrome in children with tethered spinal cord. J Neurosurg 2006;105(4 Suppl):261-4. Yeh DD, Koch B, Crone KR. Intraoperative ultrasonography used to determine the extent of surgery necessary during posterior fossa decompression in children with Chiari malformation type I. J Neurosurg 2006;105(1 Suppl):26-32. Johnston JM, Jr., Mangano FT, Ojemann JG, Park TS, Trevathan E, Smyth MD. Complications of invasive subdural electrode monitoring at St. Louis Children's Hospital, 1994-2005. J Neurosurg 2006;105(5 Suppl):343-7. Mangano FT, Bradford AC, Mittler MA, Valderrama E, Schneider SJ. Astroblastoma. Case report, review of the literature, and analysis of treatment strategies. J Neurosurg Sci 2007;51(1):21-7; discussion 27. Mangano FT, Menendez JA, Smyth MD, Leonard JR, Narayan P, Park TS. Pediatric neurosurgical injuries associated with all-terrain vehicle accidents: a 10-year experience at St. Louis Children's Hospital. J Neurosurg 2006;105(1 Suppl):2-5.

Page 242 Cincinnati Children's Research Foundation 2006­07 Annual Report

Smyth MD, Limbrick DD, Jr., Ojemann JG, Zempel J, Robinson S, O'Brien DF, Saneto RP, Goyal M, Appleton RE, Mangano FT, Park TS. Outcome following surgery for temporal lobe epilepsy with hippocampal involvement in preadolescent children: emphasis on mesial temporal sclerosis. J Neurosurg 2007;106(3 Suppl):205-10. Vadivelu S, Mangano FT, Miller CR, Leonard JR. Multifocal Langerhans cell histiocytosis of the pediatric spine: a case report and literature review. Childs Nerv Syst 2007;23(1):127-131.

2006­07 Annual Report Cincinnati Children's Research Foundation

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