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ISCN

An International System for Human Cytogenetic Nomenclature (2009)

Editors

Lisa G. Shaffer Marilyn L. Slovak Lynda J. Campbell

This publication updates the now classic system of human cytogenetic nomenclature prepared by an expert committee and published in collaboration with Cytogenetic and Genome Research (formerly: Cytogenetics and Cell Genetics) since 1963. Revised and finalized by the ISCN Committee and its advisors at a meeting in Vancouver, B.C., in October 2008, the ISCN 2009 updates, revises and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication that supersedes all previous ISCN recommendations. What is new in ISCN 2009? · New idiograms at all band levels have been revised based upon higher-resolution analysis of banded chromosomes · The neoplasia nomenclature has been revised to allow the use of idem or stemline/sideline notation to describe clonal evolution · New examples reflecting unique situations are included in most chapters · The nomenclature for microarray results has been revised to accommodate any platform and provides detailed and short systems of description · A nomenclature for MLPA results has been introduced ISCN 2009 is thus an indispensable reference for human cytogeneticists, technicians and students for the interpretation and communication of human cytogenetic nomenclature.

ISCN 2009 An International System for Human Cytogenetic Nomenclature (2009) Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature Published in collaboration with `Cytogenetic and Genome Research' Editors: Shaffer, L.G. (Spokane, Wash.); Slovak, M.L. (Duarte, Calif.); Campbell, L.J. (Fitzroy, Vic.) VI + 138 p. plus fold-out, 11 fig., 4 tab., soft cover, 2009 CHF 43.­ / EUR 30.50 / USD 43.00 ISBN 978­3­8055­8985­7

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Fields of Interest: Genetics, Molecular Biology, Chromosomes, Human Genetics

Published in collaboration with

2009

ISCN 2009

An International System for Human Cytogenetic Nomenclature (2009)

Main Headings · Historical Introduction · Normal Chromosomes · Symbols and Abbreviated Terms · Karyotype Designation · Uncertainty in Chromosome or Band Designation · Order of Chromosome Abnormalities in the Karyotype · Normal Variable Chromosome Features · Numerical Chromosome Abnormalities · Structural Chromosome Rearrangements · Chromosome Breakage · Neoplasia · Meiotic Chromosomes · In situ Hybridization · Copy Number Detection

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ISCN 2009

An International System for Human Cytogenetic Nomenclature (2009) ISBN 978­3­8055­8985­7 Please send: 1 copy: 2 copies: 3­4 copies: 5­9 copies: CHF 43.­/EUR 30.50/USD 43.00 each CHF 41.­/EUR 29.50/USD 41.00 each CHF 40.­/EUR 28.50/USD 40.00 each CHF 38.­/EUR 27.­/USD 38.00 each

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Still available ­ ISCN 2005 (Table only)

five-copy set(s) of The Normal Human Karyotype G- and R-bands Reproduced from ISCN 2005 CHF 20.­ / EUR 14.50 / USD 20.00 ISBN 978­3­8055­8046­5 Prices subject to change EUR price for Germany, USD price for USA only For easy ordering or information about other Karger publications log on to: www.karger.com Postage and handling free with prepayment Payment

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A leading journal on chromosome and genome research

During the last decades, `Cytogenetic and Genome Research' has been the leading forum for original reports and reviews in human and animal cytogenetics, including molecular, clinical and comparative cytogenetics. In recent years, most of its papers have centered on genome research, including gene cloning and sequencing, gene mapping, gene regulation and expression, cancer genetics, comparative genetics, gene linkage and related areas. The journal also publishes key papers on chromosome aberrations in somatic, meiotic and malignant cells. Its scope has expanded to include studies on invertebrate and plant cytogenetics and genomics. Also featured are the vast majority of the reports of the International Workshops on Human Chromosome Mapping, the reports of international human and animal chromosome nomenclature committees, and proceedings of the American and European cytogenetic conferences and other events. In addition to regular issues, the journal has been publishing since 2002 a series of topical issues on a broad variety of themes from cytogenetic and genome research.

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Editor: Michael Schmid

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KP 09009 (21.03.09) Printed in Switzerland (1.35, 1.04, 1.35)

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