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CURRICULUM VITAE

Professor Robert J Norman BSc (Hons), MBChB(Hons) MD, FRANZCOG, FRCPA, FRCPath, FRCOG, CREI

April 2009

Name: Contact Details:

Professor Robert John NORMAN Robinson Institute Discipline of Obstetrics and Gynaecology School of Paediatrics & Reproductive Health Faculty of Health Sciences University of Adelaide Level 6, Medical School North ADELAIDE SA 5005 Tel: +61 8 8303 8166 Fax: +61 8 8303 6100 e-mail: [email protected] Australian 19 June, 1949 Male Married ­ Susan Gay Children Michael 1976 David 1978 Rachel 1984 1972 1974 1983 BSc (Hons) Anatomical Sciences, First class University of Birmingham MB ChB (Hons) University of Birmingham MD University of Natal, Durban

Citizenship: Date of birth: Gender: Marital status:

Qualifications:

Current Appointment:

2008 - Director, Robinson Institute, University of Adelaide 2008 ­ Consultant gynaecologist, Royal Adelaide Hospital

Fellowships:

1995

1994 1993

1989 1984

1979

Fellow of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (FRANZCOG) Fellow of the Royal College of Pathologists of Australia (FRCPA) CREI (Reproductive Endocrinology and Infertility Subspecialty of the Royal Australasian Society of Obstetrics & Gynaecology) Fellow of the Royal College of Obstetricians and Gynaecologists (UK) (FROG) Member of the Royal College of Pathologists (UK) ­ Chemical Pathology: Endocrine Biochemistry subspecialty (MRCPath) Member of the Royal College of Obstetrics & Gynaecology (UK); Fellow of the College of Obstetrics & Gynaecology (South Africa). (FCOG (SA))

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Registration:

Registered in South Australia as specialist in Obstetrics & Gynaecology and Chemical Pathology (General #10810, Specialist #2243). 1984 Registered with GMC (UK) (#2889427). 1983 Registered with SA Medical & Dental Council as specialist (#8214). 1979-1983 Registered with SA Medical & Dental Council as medical practitioner (#1986). 1974 Registered with Medical and Dental Council, Zimbabwe. Member of the following Societies: Androgen Excess Society (AES) (President 2007-8) American Society of Reproductive Medicine (ASRM) Australasian Menopause Society (AMS) Australian Society of Obesity (ASO) Society of Reproductive Biologists (SRB) Endocrine Society of America Endocrine Society of Australia European Society of Human Reproduction and Embryology (ESHRE) Fertility Society of Australia (FSA) International Menopause Society Limoncello Society SA Association of Clinical Biochemists (SAACB) Society for the Study of Reproduction (SSR) 1988-90 Gribbles and Clinpath Pathology 2002 NHMRC consultancy "Adequacy of Supply of Excess ART embryos for research".

1988

Affiliations:

Consultancies:

Board Membership:

2008 ­ present Member of the Centre of Clinical Research Excellence (CCRE) Advisory Board. 2008 ­ present Board member of Asia Pacific Initiative for Reproduction (ASPIRE) 2008 ­ 2011 Editorial Board Member of Fertility and Sterility Journal 2007 ­ present Member of The Queen Elizabeth Research Foundation Research Advisory Committee 2007-2009 Deputy Member of SA Council on Reproductive Technology as nominee of the Council of the University of Adelaide 2006-2007 Member of RANZCOG Research Foundation Board of Directors 2006 ­ 2008 Member of RANZCOG Research Foundation Scholarship Selection Committee 2006 ­ present University of Adelaide representative on Research Committee of the Channel 7 Children's Foundation of SA Inc. 2004­ 2007 Member Novartis Consumer Health Australia Advisory Board

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1999-2004

Director Repromed Board

Scholarships and Awards:

2007 2006 2005 2001 NHMRC award ­ named one of 10 of the Best Great Minds in Australian Research Finalist in Premier's Science Excellence Awards for Research Leadership Finalist in Premier's Science Excellence Awards for Research Leadership Australasian Menopause Society Award/Novo Nordisk Award. (Most prestigious award offered by the Australasian Menopause Society and recognizes a distinguished person in the field of menopause, who has given much of their life to making a significant contribution to this field. Awarded every two years). SA Great Award for Best Health Company South Australia (CEO Repromed ) South Africa Medical Research Council scholarship to Nobel Prize winner's meeting, Germany ICI Clinical Research Scholarship, Dept. Reproductive Physiology, St Bartholomew's Hospital UK. Nuffield Dominions Travelling Scholarship to Britain, Dept. Anatomy, University of Birmingham, UK City of Salisbury Scholarship to study Medicine in Salisbury, Rhodesia

2001 1987 1983 1971 1968

Previous Appointments:

2004 ­ 2008 Director, Research Centre for Reproductive Health, The University of Adelaide, L6, Medical School North, Adelaide SA 5005 Professor, Obstetrics & Gynaecology, The University of Adelaide, L6, Medical School North, Adelaide SA 5005 Professor in Obstetrics & Gynaecology, The Queen Elizabeth Hospital, The University of Adelaide Head of Clinical and Scientific Services, Repromed Head (CEO) Repromed Pty Ltd Head, Reproductive Medicine Laboratories, The University of Adelaide Associate Professor in Obstetrics & Gynaecology, Reproductive Medicine Unit, The University of Adelaide, The Queen Elizabeth Hospital. Senior Lecturer in Obstetrics & Gynaecology, The University of Adelaide, The Queen Elizabeth Hospital Director of the Reproductive Endocrine Laboratory, The Queen Elizabeth Hospital. Associate Professor, Dept of Chemical Pathology, University of Natal, Durban (Deputy Head of Department). Specialist, Gynaecological Endocrine Clinics King Edward Vlll & R.K. Khan Hospitals, Endocrine Clinic, Addington Hospital, Durban Head, Chemical Pathology Laboratory, Addington, King Edward Vlll Hospitals, Durban Visiting Specialist, Endocrine Clinic, Addington Hospital, Durban. Honorary Consultant in reproductive endocrinology, Dept of Obstetrics & Gynaecology (Prof R H Philpott). Senior Pathologist/Senior Lecturer, University of Natal.

1998-2004

1993-1998

1987

1986

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1985

1984

1983

1979-1982

1978 1976-1978 1975

Senior Lecturer, Dept of Chemical Pathology, University of Natal. Member of the Medical Research Council/Preclinical Diagnostic Chemistry Research Group. Consultant Chemical Pathologist, Addington Hospital, Durban. Clinical Research Fellow, St Bartholomew's Hospital, London, UK (Dept of Reproductive Physiology : Prof T. Chard). Clinical Assistant, St Bartholomew's Hospital, London UK (Dept of Endocrinology : Profs G.M. Besser and L.H. Rees) Senior Lecturer, Dept of Chemical Pathology, University of Natal. Member of the Medical Research Council/Preclinical Diagnostic Chemistry Research Group. Consultant, Gynaecological Endocrine Clinic, King Edward Vlll & R.K. Khan Hospitals. Visiting Lecturer, Dept of Obstetrics & Gynaecology, University of Cape Town. Registrar in Chemical Pathology (Prof S.M. Joubert), University of Natal and King Edward Vlll Hospital, Durban Member of Medical Research Council/Preclinical Diagnostic Chemistry Group. Registrar in Medicine (Prof M Gelfand), Harare Hospital, Salisbury General Practice ­ Army service (6 months). Registrar in Obstetrics & Gynaecology (Prof H Rees), Harare Hospital, Salisbury Internship (Surgery & Medicine) Harare Hospital, Salisbury, Rhodesia

Current Institutional Affiliation:

The University of Adelaide

International Collaborators:

1996 A/Prof Richard Legro, Department of Obstetrics and Gynaecology, Penn State University, Hershey. PA, USA Project involving identification of genetic factors that influence the pathology of polycystic ovary syndrome. Dr Jonathan Lord, United Kingdom. Insulin sensitising drugs and PCOS Dr Ricardo Azziz, Chair, Department of O&G, Cedars-Sinai Medical Center, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA Research collaboration on PCOS Dr Dan Dumesic, Primate Centre, Wisconsin, USA. Project involves exploration of androgen signalling in cells from normal and polycystic ovaries.

2001 2003 -

2004 -

National Collaborators:

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2004 2004 2003 2003 -

Professor Jock Findlay, Deputy Director, Prince Henry's Institute of Medical Research, Monash University, Victoria, Australia Professor David Handelsman, Director ANZAC Research Institute and Department of Andrology, Concord Hospital, Concord, NSW, Australia. A/Prof Martha Hickey, University of Western Australia School of Women's and Infant's Health, Subiaco, WA, Australia Professor Kerin O'Dea, Director, Menzies School of Health Research, Casuarina, NT, Australia

Local Collaborators:

2000 Professor Gary Wittert, Head Department of Medicine, University of Adelaide, Adelaide, Australia Prof Peter Clifton, CSIRO Human Nutrition, Adelaide, Australia A/Prof Manny Noakes, CSIRO Human Nutrition, Adelaide, Australia Professor Caroline McMillen, School of Molecular and Biomedical Sciences, University of Adelaide, Adelaide, Australia Professor Caroline McMillen, Pro Vice Chancellor and Vice President; Research and Innovation, University of South Australia

2000 2000 2004 -2006 2007 -

Invited Seminars/Symposium Presentations

International Invitations: 2008 13-14 December 2008. Invited to Co-Chair a Schering-Plough Fertility Scientific Consultant Meeting in Hong Kong. (All expenses paid) 8-12 November 2008, invited to Chair the Scientific Program Symposium on PCOS as a Lifetime Metabolic Disorder at the ASRM 2008 64th Annual Meeting in San Francisco, USA 30-31 August 2008, invited to give plenary lecture at the Taiwanese Society for Reproductive Medicine Annual Meeting in Taipei. Subjects: 1. Infertility, IVF and lifestyle ­ facing the next frontier for treatment. 2. PCOS and androgen excess in 2008: current concepts and treatments. (All expenses paid) 15-18 June 2008. Invited to chair a scientific symposium at the 2008 Endocrine Society Meeting in San Francisco, USA. "Controversies in the Definition: What are the Implications?" 18-20 April 2008, invited to be plenary speaker at the Seminar in Safety in ART in Hangzhou, China. Title: Safety in AET and the Health of Reproduction and Inheritance. (All expenses paid) 11 April 2008, invited to speak on "Consensus view of what is PCO" and "Clinical Management of PCOS" at the Serono Symposia "Polycystic

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Ovary Syndrome" Pre-ASPIRE conference in Singapore. (All expenses paid) 26-29 March 2008, invited by the O&G Society of Singapore and the College of O&G of Singapore to give four talks at the 9th Post Graduate Refresher Course 2008 in Singapore. 30 January ­ 1 February 2008, invited to be plenary speaker on "Improving fertility treatment outcomes : the final frontier?" at the Updated in Infertility Treatment 2008 Conference in Cape Town, South Africa. (All expenses paid) 2007 Keynote lecture on "Approaches to Lifestyle Management in PCOS", chairing a session on Epidemiology of PCOS and taking part in the debate "Metformin should be first line therapy for women with PCOS" at Royal College of Obstetricians and Gynaecologists and ESHRE symposium 15-16 November 2007 in London. (All expenses paid) Invited to give the Ian Johnston Memorial Lecture at the Fertility Society of Australia 2007 conference in Hobart, 9-12 September 2007. Subject: "Empty Cots and Silent Spring in an Age of Plenty. What our lifestyle is doing to our Reproductive Health". (All expenses paid) Invited speaker at the ESHRE 2007 Pre-congress course on "The metabolic syndrome in PCOS" and "Dietary Interventions" in Lyon, France 1 July 2007. (Registration paid) Invited to give plenary lecture on "Obesity, famine and reproductive health" at the 19th World Congress on Fertility and Sterility in Durban, South Africa April 29 ­ May 3 2007. (All expenses paid) Invited to give plenary lecture "PCOS in 2007 ­ evidence-based diagnosis and management" at the 6th Singapore Congress in Obstetrics and Gynaecology 21-22 March 2007 and also speaking at precongress workshop on "Is ICSI safe?". (All expenses paid) Keynote speaker at ESHRE/ASRM symposium on "Life-style changes" in Thessaloniki Greece 1 March 2007. (All expenses paid) 2006 Plenary speaker at the Controversies in Reproductive Medicine Conference in Mumbai, India 15-17 September 2006. Involved in all three days on "... a Consensus in Clinical Practice". Gave the Dr Dossibai JR Dadbhoy Silver Jubilee Oration "The Reproductive Revolution ­ how it will change our World". (All expenses paid) Invited to speak at ICO 2006, the 10th International Congress on Obesity in Sydney, Australia from 3-8 September 2006. "Impact of obesity on reproduction". (All expenses paid) Symposium speaker at the 2006 SSR Annual meeting, Omaha, Nebraska USA. "Nutrition, Obesity and Human Reproduction", 29 July ­ 1 August 2006. (Registration paid)

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Invited to speak at the ENDO 2006 88th Annual Meeting in Boston USA from 24-27 June 2006 and give two 50 minute presentations on "Fertility and Polycystic Ovary Syndrome". (Meet the Professor series) Symposium speaker at the ESHRE meeting in Prague 18-21 June 2006, on "Fertility in obese women". (All expenses paid) Plenary speaker at the Asia Fertility Expert Meeting 21-22 April 2006 in Ho Chi Minh City, Vietnam. "PCOS and Dietary Intervention". Invited to Chair a Workshop session on PCOS also. (All expenses paid)

2005

Invited discussant in scientific discussions at PCOS meeting in Avallon, France, 6-9 October 2005. Keynote speaker at Androgen Excess Society 2nd Special Scientific Meeting at Ravello, Italy, September 30 ­ October 1 2005. "Diet and Lifestyle". (All expenses paid)

Keynote speaker at ESHRE meeting in Capri, Italy 3 - 4 September 2005. "Fertility in Obese Women" and "Endocrine Activities of Fat Tissue". (All expenses paid) Symposium speaker at the 2005 Annual Meeting of the Endocrine Society, 4-7 June in San Diego, California USA on "Medical management : An Evidence Based Approach" (regarding hyperandrogenism and hirsutism). (All expenses paid) Moderator of Androgen Excess Society Third Annual Meeting Session "Advances in PCOS". 3 June 2005 in San Diego, California USA. Plenary Speaker at the Updates on Polycystic Ovarian Syndrome symposium organised by the Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong. 20 March 2005. "Health related issues in polycystic ovary syndrome" and "Use of metformin in polycystic ovary syndrome". (All expenses paid) 2004 Plenary speaker to 2nd Annual world Congress on the Insulin Resistance Syndrome, 18 ­ 20 November 2004, Los Angeles. USA. "Diet, exercise and lifestyle modification in women with Polycystic Ovary Syndrome". (All expenses paid) Symposium speaker at ENDO 2004 Conference in Los Angeles, USA 16-19 June. Topic "Role of Insulin-sensitizing Agents in PCOS". (Registration paid) Symposium speaker at the 18th World Congress on Fertility and Sterility 23-28 May 2004 in Montreal Canada. Topic "Diagnosis and etiology" in trilogy "Polycystic Ovary Syndrome". (Registration paid)

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Plenary speaker at the Evidence Based Management of Anovulation, Joint RCOG/ESHRE Meeting, RCOG, London. 22-23 April 2004. Topic "Weight control and PCOS". (All expenses paid) 2003 Symposium Speaker to American Society for Reproductive Medicine 59th Annual Meeting (October 11-15 2003) San Antonio, Texas. "Cardiovascular Risk in the Reproductive Age Women with PCOS" "Lifestyle interventions in women with PCOS", "Insulin Sensitisers to achieve pregnancy in women with PCOS", "Gonadotropins and IVF in the PCOS Population: What to do differently". (Partial expenses paid) Symposium Speaker to the RANZCOG Annual Scientific Meeting (1719 September 2003) in Auckland, New Zealand. "The role of obesity in reproduction" and "Only one at a time ­ reducing multiple pregnancies". (All expenses paid) Visiting Professor at the 2003 Rising Stars Symposium (10, 11 September 2003) in Perth WA. "The Reproductive Revolution ­ have we gone too far?" (All expenses paid) Endocrine Society Meeting, Philadelphia (USA) (19-22 June 2003) invited to lead two Meet the Professor sessions on "Ovulation Induction and Assisted Reproduction". (Registration paid) Speaker at closed international workshop on "PCOS consensus/controversy" (ASRM/ESHRE Sponsored) Netherlands (1-4 May 2003). (All expenses paid) Serono Symposia International Symposium ­ An introduction to Quality Management Systems in the ART Clinic. "Quality Management Systems in ART : The Australian Experience" New Zealand (17 January 2003) (All expenses paid) 2002 Fertility Society of Australia "Metformin and PCO" workshop (23-27 October) (All expenses paid) Plenary speaker at Fertility Society of Australia "Blastocysts Single Embryo Transfer and Multiple Pregnancy Rates" 23-27 October) (All expenses paid) Endocrine Society Meeting invited to lead the "Meet the Professor" session on PCOS (19-22 June) (Registration paid) Endocrine Society Meeting "Polycystic Ovary Syndrome ­ Current Controversies" San Francisco (19-22 June) 2001 Speaker at 34th International Congress of Physiological Sciences, IUPS 2001 satellite meeting. "Regulation of Ovarian Function", Wallaceville, New Zealand (23-24 August). (All expenses paid) Symposium speaker at 1st Scientific Meeting of the Asia-Pacific Menopause Federation "Changes in body weight and composition" Seoul Korea (26-29 May). (All expenses paid) 2000 Symposium speaker at Tamil Nadu State Obstetrics & Gynaecology Conference ­ "Controversies in HRT", "Understanding PCOS". India (30th November ­ 2nd December). (All expenses paid)

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Speaker at National Institute of Health Conference on PCOS: Basic Biology, Intervention and Treatment "Lifestyle Modification" North Carolina, USA (17-20 September). (All expenses paid) Speaker at the XVllth Asian and Oceanic Congress of Obstetrics & Gynaecology "PCOS ­ Genetic or environmental?" Singapore (9-14 July) (All expenses paid) 1999 Symposium speaker American Society for Reproductive Medicine "Weight and Reproductive Function" (28 September). (Registration paid) Speaker at National University of Singapore "Weight and Reproductive Function ­ Lessons for Polycystic Ovary Syndrome" (13 September). (All expenses paid) Plenary speaker at World Congress on Practical Infertility Management, Mumbai, India. "Obesity and Infertility", "Human Cloning is the Absolute Evil" (debate), "Fertility enhancing procedures" and "Embryo Transfer Techniques" (10-12 September). (All expenses paid) Plenary speaker at Polycystic Ovary Syndrome Association, Chicago, Illinois "How diet and exercise make a difference: Lessons from Fertility Fitness" (4-6 June). (All expenses paid) Invited discussant International Consensus Meeting on Polycystic Ovary Syndrome, Athens, Greece. (All expenses paid) Speaker at International Meeting on Ovarian Hyperstimulation, Valencia Spain. "Cytokines ­ the missing mediators in ovulation?". (All expenses paid) Speaker at International Meeting on Advances in Fertility Options, Langkawi Malaysia, Organon. (All expenses paid) Society for Endocrinology, Metabolism & Diabetes of South Africa Congress, Durban "Structure of hCG in ectopic pregnancies". 1998 International Meeting on :Polycystic Ovary Syndrome, Athens, Greece. International Meeting on Ovarian Hyperstimulation, Valencia Span. "Cytokines ­ the missing mediators in ovulation". International Meeting on Advances in Fertility Options, Langkawi, Malaysia Society for Endocrinology, Metabolism and Diabetes of South Africa Congress, Durban "Structure of hCG in ectopic pregnancies". 1987 1986 South African Hypertension Society, University of Cape Town, South Africa "Prostaglandins in pre-eclampsia" South African Society of Obstetrics & Gynaecology, Medunsa "Prostaglandins and labour" University of Western Ontario, London, Canada, National Institutes of Health, NICHHD "Thyroid function in trophoblastic disease" and Prostaglandins and dysfunctional labour in women" University of the Witwatersrang "The onset of labour" University of Sheffield "The onset of labour in human pregnancy"

1985 1984

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University of London (St Bartholomew's Hospital, London Hospital, Whitechapel) "The onset of labour in twin pregnancies" 1983 1982 University of Cape Town (Visiting Lecturer, Dept of Obstetrics & Gynaecology) "The importance of prostaglandins in reproduction" Congress of South African Society of Pathologists "The onset of labour ­ mechanisms and causes"

National Invitations 2008 6 December 2008, invited to be a key speaker at the SA Italian Medical Association symposium on Obesity at the Novotel, Barossa Valley, SA. (All expenses paid) Invited to speak at the Fertility Society of Australia 27th Annual Scientific Meeting in Brisbane, Australia from 19-22 October 2008. "Preparing for Pregnancy ­ Preconceptional Rights and Responsibilities" and "Evidence for Metformin in Ovulation Induction". 19 October 2008. Invited to speak at the Serono Symposia International, Brisbane, Australia on "Novel approaches in Ovarian Stimulation for IVF". Fertility Society of Australia Conference 2008 on "Novel approaches in ovarian stimulation for IVF" (All expenses paid) 23-24 August 2008. Invited to speak at the inaugural Australian Jean Hailes Foundation collaborative research meeting on PCOS. Melbourne. 24 May 2008, invited to speak at the Inaugural RANZCOG CREI Conference in Sydney on "The role of CREIs in the Leadership in Clinical Practice of Reproductive Endocrinology and Infertility". (All expenses paid) 18 May 2208, invited to speak at Merck Serono symposium in Sydney on "What is the best stimulation protocol for poor responders" and "Optimal stimulation protocols for IVF patients with PCO" 13 May 2008, invited to speak on "How do we define and treat PCOS ­ international consensus statements" at the RACP Congress in Adelaide. 20 February 2008, invited to speak at a public seminar on PCOS at the Florey Lecture Theatre, University of Adelaide 2007 Invited to speak at 5th International Congress of the Society for the Developmental Origins of Health and Disease, in Perth, Western Australia from 6-10 November 2007. Subject: "Genetic/epigenetic and environmental origins of PCOS". (All expenses paid) Invited to present a seminar at the Mothers and Babies Research Centre of the Newcastle University at the John Hunter Hospital in Newcastle, on 18 October 2007. Subject: "Feast, Famine and Fecundity". (All expenses paid) Invited to speak at the Australasian Menopause Society Annual Meeting in Adelaide on Saturday 15 September 2007 on Polycystic Ovary Syndrome.

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Invited to speak at the University of Adelaide's Research Tuesday Public Forum on "The Reproductive Revolution ­ Have We Gone Too Far?" on 14 August 2007 at University of Adelaide. Invited to speak at the Dame Roma Mitchell Breast and Prostate Cancer Meeting at Renmark, SA on 18 May 2007. Subject: "Clinical Perspective of Ovarian Function". Invited to speak at the Adelaide Women and Children's Health Update and Education Day, 12 May 2007 in Adelaide. Subject: "Management of PCOS in General Practice" 2006 Invited to speak at the Annual Scientific Meeting of RANZCOG in Perth, Western Australia from 15-18 October 2006. Two lectures. "Reproductive problems associated with obesity" and "Fertility after 40". (All expenses paid) Invited to speak at The Fertility Society of Australia 2006 Conference, Sydney, Australia from 22-25 October 2006. "Mono-follicular Ovulation". (All expenses paid) Invited to speak at ICO 2006, the 10th International Congress on Obesity in Sydney, Australia from 3-8 September 2006. "Impact of obesity on reproduction". (All expenses paid) Invited to Chair the Plenary Session on Advances in Reproductive Technology at the Human Reproductive Health Through the Ages Conference, Adelaide 7-10 March 2006. Invited to speak at the Sydney Menopause Centre, Royal Hospital for Women's Annual Hormone and Women's Health Update and Education Day. "PCOS ­ Management in General Practice". Sydney, 18 February 2006. Invited to speak at ICO 2006, the 10th International Congress on Obesity in Sydney, Australia from 3-8 September 2006. "Impact of obesity on reproduction". (All expenses paid) 2005 Invited to give the introductory talk on "Prevention of Multiple Gestation in IVF" at the Bertarelli Foundation sponsored meeting on Multiple Gestation in Melbourne. Invited to speak at ICO 2006, the 10th International Congress on Obesity in Sydney, Australia from 3-8 September 2006. "Impact of obesity on reproduction". (All expenses paid) Invited speaker to the 5th Annual Conference of the Polycystic Ovarian Syndrome Association of Australia Inc, Adelaide, 5 November 2005. "The Role of Metformin", "Medical Aspects of Hirsutism" and taking part in a question and answer session. Guest speaker at the Centre for Women's Health Research, Department of O&G, Monash University Faculty of Medicine, Melbourne, Tuesday 25 October 2005. (All expenses paid) Plenary speaker at The Queen Elizabeth Hospital Research Day. "The Reproductive Revolution ­ How TQEH led the Field". 21 October 2005, Adelaide.

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Invited speaker to the Serono Symposia International Fertility Nurse Program in ART, Sydney, July 22-25 2005. "Review the Urinary History and Introduction of Recombinant Products" and "How Couples Can Increase Fertility without Treatment". (All expenses paid) Invited speaker to the Perinatal Society of Australia & New Zealand 9th Annual Congress, Adelaide, SA 13-16 March 2005. "Lessons from Science for Establishing Future Reproductive Health Priorities" 2004 Speaker at POSSA Conference, 13 November 2004 in Melbourne, Australia. Topics: "What is PCOS ­ Origins and Evidence", "Weight Loss and the Impact on Health", "PCOS Update ­ latest research". (All expenses paid) Speaker at a one day symposium run by the Infertility Treatment authority to review the issues associated with the law and the use of reproductive technologies, including genetic testing. Title: "Looking forward ­ what the future holds for reproductive technologies". Melbourne, Australia, 27 October 2004. (All expenses paid) Speaker at the Fertility Nurses of Australia workshop, 9 October 2004, Adelaide, Australia. Topic "Sexuality and Gender Differentiation". Speaker to Fertility Society of Australia Annual Scientific Meeting, 10 ­ 13 October 2004, Adelaide, Australia. Topic " PCOS and Treatment". Speaker at the 7th Annual North Queensland Obstetrics Gynaecology and Neonatology Meeting, 10 ­ 12 September 2004 in Cairns, Qld. Topic: "PCOS ­ Aetiology and Diagnosis". (All expenses paid) Plenary speaker at the Royal College of Pathologists of Australasia and Australasian Association of Clinical Biochemists Chemical Pathology Course (16-20 February 2004) in Glenelg, South Australia. Topic "Testosterone measurement". 2003 Invited plenary speaker to the 7th Australasian Menopause Society Congress (13-15 November 2003) in Hobart. "Epidemiology and fertility and facts about outcomes in older pregnancies". (All expenses paid) The Australasian Sexual Health Conference, Adelaide. "The Future of Reproductive Medicine" (15 May) Serono Symposia International Symposium on The Polycystic Ovary. "Management of the Metabolic Syndrome, Including Follow Up", Melbourne, Australia (24 November). (All expenses paid) Royal Australian and New Zealand College of Obstetricians and Gynaecologists Annual Scientific Meeting. "Is PCOS an inherited Disease?", Melbourne, Australia (28th October ­ 1st November). (All expenses paid) Immune Deviation and Reproductive Function "Immune dysregulation and ovarian disorders" Lorne, Victoria (19-21 February). (All expenses paid) 2000 1999 Fertility Society of Australia PCOS Symposium "Insulin modifying approaches" Canberra, Australia (30 April). (All expenses paid) 11th World Congress on In Vitro Fertilization and Human Reproductive Genetics, Sydney. Postgraduate Course "Assisted Conception: Women and Men" (9-14 May). (All expenses paid)

2001

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The Australasian Sexual Health Conference, Adelaide. "The Future of Reproductive Medicine" (15 May) 1998 Prince Henry's Institute of Medical Research Symposium, Melbourne, "Polycystic ovaries ­ the influence of genes and environment". (All expenses paid) Family Planning Australia Inc. Biological Sciences Meeting, Canberra "Weight and Fertility". (All expenses paid) Royal Australian College of Obstetricians & Gynaecologists Annual Scientific Meeting, Canberra "Early Menopause". (All expenses paid) Endocrine Society of Australia Seminar Meeting, Adelaide "Insulin resistance in polycystic ovary syndrome"

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Undergraduate and Post-graduate Teaching

Past and Present Students PhD 2009 ­ present Lisa Akison. "Progesterone-receptor mediated coordination of oocyteoviduct communication during ovulation". Co supervisor with Dr R Robker, Prof R Ivell 2006 ­ present Siew Lim. PhD "Determinants of responsiveness to dietary intervention in PCOS women to improve reproductive outcomes". 2005 ­ present Cadence Minge - PhD "The effects of diet induced insulin resistance ovarian function". 2000 ­ 2005 David Sharkey (co-supervisor with A/Prof Sarah Robertson) "Seminal Plasma Regulation of the Post-Coital Inflammatory Response in the Human Cervix"

2003 ­ present Jacqueline Boyle (co-supervisor with Prof Kerin O'Dea) "Polycystic ovarian syndrome in indigenous women". 2000 - 2006 Theresa Hickey ­ part time May 2000, full time May 2003 - present "Androgen receptor mediated activity in the ovary : implications for polycystic ovary syndrome". Lisa Moran ­ "Dietary treatment of PCOS" Kylie Van Der Hoek - PhD "The role of la and F480 positive cells in ovarian function" Leanne Roberts ­ PhD "The effect of high estrogen and/or high progesterone hormonal environments induced by oral contraceptives and early pregnancy on the exercise status of young women" (cosupervisor) Priya Duggal ­M.MedSc/PhD "Leptin and its receptors in the rodent ovary" Louise Gameau ­ PhD Marmoset Chorionic gonadotrophin and cytokines in the embryo. Melinda Jasper ­ PhD GM-CSF and CSF-1 in the ovary Nigel Bonello ­ PhD Adhesion molecules in the ovary Dean Bacich ­ PhD Molecular heterogeneity of the LH receptor Ling-jia Wang ­ PhD Cytokines and human ovarian function Sebastio de Medeiros ­ PhD Structure of beta core of hCG

2002 ­2007 2000 ­ 2005 2001 ­ 2004

1999 ­ 2001 1994 ­ 1998 1993 ­ 1997 1993 ­ 1997 1992 ­ 1996 1988 ­ 1991 1988 ­ 1991 MD 1995 ­ 1996 1987 ­ 1992 1985 ­ 1988 1983 ­ 1987 1982 ­ 1986 M.Sc/M.Med.Sc 2004 ­ 2007

John Latimer ­MD Cytokines and human ovarian cancer Shamin Mahabeer ­ MD Insulin resistance in PCOS Robert Buck ­ MD Beta core fragment of hCG Thavan Padayachi ­ MD Steroid receptors and labour Kogie Reddi ­ MD Prostaglandins and dysfunctional labour

Victoria Tsagareli "The effects of a short term use of a very low calorie diet in overweight or obese women on infertility treatment outcomes".

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1996 ­ 1998 1992 ­ 1994 1987 ­ 1989

Shinetugs Bayanbileg ­ M.Med.Sc Colony stimulating factor 1 in human ovarian function Vivienne Pascoe ­M.Sc Leukocytes in the ovary Raazia Mahomed ­ MSc Monoclonal antibodies to alpha subunit of glycoproteins

B.Sc (Hons) 2007 2003 2001 2001 2001 1998 1998 1992 1992 1991 1990 1990 1989

Amanda Proprzeczny B.Sc (Hons) Cadence Haynes B.Sc (Hons) Andrea Gordon 2001 BSc (Hons) Jessica Holding BSc (Hons) "IVF Children's understanding of biological conception and inheritance" (co-supervisor) Lisa Moran B.Sc (Hons) "Dietary composition in restoring reproductive and metabolic physiology in obese women with PCOS". Natalie Ryan B.Sc (Hons) GM-CSF and the ovary Rebecca Gehling B.Sc (Hons) TNF and PCOS Melinda Jasper B.Sc (Hons) GM-CSF and the ovary Nigel Bonello B.Sc (Hons) Plasminogen activator in the ovary Dean Bacich B.Sc (Hons) Beta core fragment and cervical cancer Kathy Govas B.Sc (Hons) An investigation of the physico-chemical and biological properties of two hCG preparations: profasi and pregyni Yuko Nakayama B.Sc 1990 Insulin resistance and PCOS Lyn Cranwell B.Sc (Hons) Ovarian cytokines

Clinical Fellows (country of origin) 2007 ­ 2008 2005 ­ 2007 2004 - 2005 2003 - 2004 2003 - 2007 2002 - 2003 2002 - 2003 2002 - 2003 1994 - 1998 1999 - 2000 1999 - 2001 1999 - 2001 1998 - 1999 1997 - 1998 1996 - 1997 1994 - 1998 1993 - 1994 1991 - 1992 Murizah Mohd Zain (Consultant gynaecologist, Malaysia) Louise Hull ( Consultant gynaecologist/Senior Lecturer, New Zealand) Preeti Dabadghao (Consultant gynaecologist, Lucknow, India) Ivan Sini (Consultant gynaecologists in private practice, Djakarta, Indonesia) Marcin Stankiewicz ( Consultant gynaecologist, Flinders Medical Centre, Adelaide) Goran Westlander (Consultant gynaecologist, Goteborg, Sweden) Kelton Tremellen (Consultant gynaecologist, Repromed, Adelaide, Australia) Ruijin Wu (Consultant in O&G, Hangzhou, People's Republic of China) Greg Phillipson (Consultant gynaecologist, Christchurch, New Zealand) Shunsaku Fujii (Consultant gynaecologist, Japan) Achamma Chandy (Consultant gynaecologist, Vellore India) Janelle McDonald (Consultant gynaecologist, Canberra, Australia) Steve Robson (Consultant gynaecologist, Australia) Hideo Tozawa (Consultant in O&G, Japan Kwo-Wei Fuh (Consultant gynaecologist, Taipei, Taiwan) Marie-Madeleine Huber-Buchholz (Consultant gynaecologist, Australia) Hideo Tozawa (Consultant gynaecologist, Japan) Mats Brannstrom (Consultant gynaecologist, Goteburg, Sweden)

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1991 ­ 1992 1990 - 1995 1985 - 1988 1987 - 1989 1982 - 1986 1983 - 1987 1981 - 1986

William Ledger (Professor in O&G, Sheffield UK) Anne Clark (Consultant gynaecologist, Sydney, Australia) Robbie Buck (Consultant gynaecologist, Republic of South Africa) Shamin Mahabeer (Consultant gynaecologist, Auckland, New Zealand) Sunkree Naidoo (Consultant gynaecologist, Durban, Republic of South Africa) Thavan Padayachi (Consultant gynaecologist, Durban, Republic of South Africa) Kogie Reddi (Consultant gynaecologist, Petermaritzburg, Republic of South Africa)

Scientific Fellows 1996-2002 Robert Gilchrist 1992 - 1996 Anthony Simula

Administrative Responsibilities:

The University of Adelaide 2007 ­present Convenor of School of Paediatrics and Reproductive Health Research Committee 2006 ­ present Member, Channel 7 Children's Research Foundation Committee 2004 ­present Director, Research Centre for Reproductive Health 2004 ­ present Co-convenor, Healthy Development Adelaide Research Cluster 2004 ­ present Academic Head, Repromed Pty Ltd 2004 Head of Clinical and Scientific Services, Repromed 1998-2004 Head (CEO) Repromed Pty Ltd 1999-2004 Director, Repromed Board 1999 Member, Review of Research Committee of the Faculty of Health Sciences 1999-2004 Representative for the University of Adelaide, Reproductive Technology Council of South Australia 1998-2004 Head, Reproductive Medicine Laboratories, University of Adelaide 1995-1998 Alternate Director, Repromed Board 1990-2004 Member, Repromed Management Committee 1994-1996 University of Adelaide representative on the Queen Elizabeth Hospital Research Foundation 1993-1998 Deputy representative for the University of Adelaide, Reproductive Technology Council of South Australia 1992-1994 Faculty Representative on the Florey Foundation 1984-1985 Member, Faculty of Dentistry Research Committee, University of Adelaide 1988-1997 Member, Faculty of Medicine Research Committee, University of Adelaide 1992-1994 Convenor, Faculty of Medicine Research Committee, University of Adelaide

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The Queen Elizabeth Hospital, Adelaide 1999-present Scientific Member, Clinical Development & Research Centre, Policy Committee, The Queen Elizabeth Hospital 1997-2002 Member, Library Services Committee, The Queen Elizabeth Hospital 1990-1997 Medical Appointments Committee, The Queen Elizabeth Hospital 1992-1993 Committee of Graduate Studies, Committee Member, TQEH 1992 Chairman of the inaugural Organising Committee, TQEH Research Day South Africa 1982-1988 1985 1986 1986-1988 1985-1988 1985-1988

Deputy Head, South African Medical Research Council Preclinical Diagnostic Chemistry Research Unit Vice-Chairman, South African Medical Research Council Workshop Community in Endocrinology. Chairman, South African Medical Research Council Workshop Community in Endocrinology Chairman of Computer Committee, Regional Laboratory Services, Durban). Head of Chemical Pathology Laboratories, Addington Hospital, and Durban, South Africa Member Faculty of Medicine Research Committee, University of Natal, Durban

Peer Review:

Granting Bodies 2007 ­ present Member, NHMRC Program Grants Committee 2006 Chair, NHMRC Grant Review Panel (GRP for reproduction, obstetrics and gynaecology, paediatrics) 2004 Chair, NHMRC Grant Review Panel (GRP for reproduction, obstetrics and gynaecology, paediatrics) 2004 ­ present NHMRC ­ Panel member Reproduction and Endocrine 1999-2003 National Health and Medical Research Council Grant Review Panel for Endocrinology and Reproduction, Chairperson (2003) 1991-1994 Scientific Advisory Committee, SIDS Association of South 1992-1994 Member and Chair, ARC Small Grants Committee, University of Adelaide 1994-1997 Member of Grants' Assignment Committee, National Health and Medical Research Council (NHMRC) 1995-1996 Member of Advisory Committee for NHMRC Program Grant Committee (de Kretser Programme Grant) 1996 Member of Biomedical Assessing Committee for New Zealand Health Research Council Regulatory Experience in Assisted Reproductive Technology For five years I was the Head of Repromed, a University company practising fertility medicine. During this time I was well aware of all the regulatory issues relevant at State and National level. I still work in an IVF company but am not a shareholder.

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I have been a member of the South Australian Council for Reproductive Technology as a University of Adelaide nominee for two 3 year terms during which I contributed to the regulatory aspects of assisted reproductive technology in South Australia. For the past three years I have been a Deputy on the SA Council for Reproductive Technology. Editorial Appointments 2009-2011 2005- 2008 2005-present 2004 ­ 2008 2003 ­ 2005 1997 ­ 2007 1996-1999 Associate Editor of Human Reproduction Member of Senior Review Panel, Human Reproduction journal (impact factor 6.2) Editorial Board RBM Online (impact factor 3.2) Human Reproduction Update Editorial Board (impact factor 6.2) Editorial Board, Human Reproduction (impact factor 3.4) Editorial Board, Climacteric Editorial Board Cochrane Collaboration Editorial Board, Maturitas

Involvement in Scientific Discipline

Professional Societies - Membership: 2007-2008 2005- 2006 2002-2005 2004-present 2003-present 1998-2004 1999-2004 President, International Androgen Excess and PCOS Society Vice-President of Androgen Excess Society Chair, Annual Program Committee, Androgen Excess Society Member of National Benefits Advisory Committee, ARC/NHMRC Research Network in Genes and Environment in Development. Committee Member Cochrane Steering Group on menstrual dysfunction and infertility Member South Australian Council on Reproductive Technology Member, Royal Australian & New Zealand College of Obstetricians and Gynaecologists Committee for Reproductive Endocrinology and Infertility Committee member, Australasian Menopause Society Secretary, Australasian Menopause Society Committee member, Australasian Society of Reproductive Biology

1993-1995 1995-1999 1994-1997

Professional Societies - Other: 2004 - 2006 Member Novartis Consumer Health Australia Advisory Board 2003 NHMRC Consultancy on Embryo availability in Australia 2003 - present Member Committee Reviewer Cochrane Collaboration Subgroup on Menopause and Menstrual Dysfunction 1995-present Member of subcommittee of the International Federation of Clinical Chemistry for Standardisation of Human Chorionic Gonadotrophin 1990 ­ present Examiner Australian Medical Council 1997 Visiting Professor to the Singapore Society of Obstetrics and Gynaecology 1996 David Curnow Memorial Lecturer, Australian Association of Clinical Biochemistry, Darwin

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1992 1979-1988

Mary Weston Visiting Professor, Universities of Natal and Cape Town, South Africa Consultant to Gribbles and ClinPath Laboratories Deputy Director SA Medical Research Council Pre-clinical Diagnostic Chemistry Research Group

Research Conference Organisation:

Programme Organising Committee, Australian Society of Reproductive Biology 1991,1997,2004Organising Committee, Fertility Society of Australia meeting 1991 Organising Committee Australian Menopause Society Annual Scientific Meeting, Adelaide 1992 Organiser, Symposium on Polycystic Ovary Syndrome, Adelaide 1997 Chair of Organising Committee, Fertility Society of Australia Annual Scientific Meeting 1997 Chair of Organising Committee Serono Symposium on Genes and Environment in Disorders of Human Reproduction 2004, 2005 Chair Program Committee, Androgen Excess Society Annual Meetings in USA 2009 Co-Chair Scientific Committee for First International Asia/Pacific Meeting on Polycystic Ovary Syndrome, Hong Kong, January 2009 1992-1994

Panel of Referees for Granting Bodies:

Referee for grants from: National Health and Medical Research Council Australian Research Council Israel Medical Research Council Health Research Council of New Zealand

Panel of Referees for Professional Journals:

Impact Factor

6.6 1.7 3.5 2.2 3.4 No IF 1.8 5.2 No IF 3.3 3.8 6.8 5.8 2.2 3.1 25.8 1.9

American Journal of Clinical Nutrition Annals of Clinical Biochemistry Biology of Reproduction Climacteric (Editorial Board) Clinical Endocrinology (Oxford) Cochrane Collaboration (Editorial Board) Endocrine 3380 Endocrinology Expert Review of Obstetrics and Gynaecology Fertility and Sterility (Editorial Board) Human Reproduction (previously Editorial Board) Human Reproduction Update (Editorial Board) Journal of Clinical Endocrinology and Metabolism Journal of Clinical Pathology Journal of Endocrinology Lancet Maturitas (previously Editorial Board)

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No IF 2.9 2.8 1.0 2.7 2.9 2.5 3.2 2.8 1.2

Medical Technology Molecular and Cellular Endocrinology Molecular Human Reproduction Nature Clinical Practice Endocrinology and Metabolism Peptides Reproduction Reproduction Fertility and Development RMB Online (Editorial Board) The American Journal of Obstetrics & Gynaecology South African Medical Journal

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Involvement in Wider Community Media Reports 2004 ­ Present:

The following are representative but do not comprise a complete list: 2009 16/3/09 ­ interviewed on Radio 5AA by Amanda Blair re oral contraception pill and pregnancy 16/3/09 ­ interviewed on Radio station 5AA re Robinson Institute 25/2/09 ­ interviewed on ABC Radio National re Robinson Institute and hormone therapy. 14/1/09 ­ The Advertiser, re shortage of research space 2008 22/10/08 ­ The Advertiser, re pre-conceptual health. 18/10/08 ­ Article in The Australian re the Robinson Institute 8/7/08 ­ interviewed by Amanda Blair on 5AA re preconception and infertility issues. 2/6/08 ­ interviewed on Radio 891 re hormone therapy and breast cancer 3/4/08 ­ interviewed on ABC1 Catalyst program re acupuncture and IVF 10/2/08 ­ The Sunday Mail re multiple births and IVF 12/1/08 ­ quoted in article in The Advertiser on pregnancy and obesity 2007 7/12/07 ­ interview on radio station Life FM re Research Centre for Reproductive Health in South Australia 30/10/07 ­ article in The Advertiser re money for research into reproductive medicine 16/10/07 ­ article in The Bulletin Magazine re Baby Blues 15/10/07 ­ interviewed by Molly Webster from UK magazine Scienceline, National Geographic Adventure on PCOS. 19/9/07 ­ interviewed on Radio 2UE by John Laws on IVF 17/9/07 ­ Interviewed on Sunrise TV program re IVF 3/9/07 ­ Interviewed by Channel 7 TV News re the reproductive debate. 3/9/07 ­ interviewed on ABC News on Rights and Responsibilities in IVF 14/8/07 ­ Interviewed on ABC 891 radio re Research Tuesday lecture to be given today "The Reproductive Revolution ­ Have we gone too far" at the Adelaide University 26/7/07 ­ Interviewed by Gabrielle Babbington, Clinical Journalist, Australia Doctor Magazine, re Outcomes for IVF Babies.

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May - Interviewed on Sydney radio 2UE by John Stanley re menopause April ­ quoted in two articles in the Medical Tribune in Singapore "Controversy over health of ART children" and "New directions in the diagnosis and treatment of PCOS" 10/4/07 ­ quoted in "The Advertiser" re HRT 3/3/07 ­ Quoted in the Weekend Australian in an article on periconceptual health. 27/2/07 - Quoted an article in The Age newspaper re frozen eggs and frozen sperm being used to create an embryo 7/2/07 Telephone interview with Gabrielle Barrington from national newspaper Australian Doctor re PCOS article in Lancet. 6/2/07 Radio interview with BBC re PCOS. 1/2/07 - Interviewed by 5AA radio station on gender selection 23/1/07 ­ Interviewed by ABC Radio Brisbane re egg timer 21/1/07 ­ Spoke with journalist for Perth Sunday newspaper re Diet for PCOS. 19/1/07 ­ Rob Norman quoted in article on twins in "The Advertiser" 18/1/07 ­ telephone interview by Advertiser journalist Claire Petty re twin research. 18/1/07 ­ telephone interview by Sun Herald journalist in Sydney re ovarian reserve, on behalf of RANZCOG 17/1/07 Interviewed on ABC radio re non ­hormonal treatment of menopause. 15/1/07 Interviewed on ABC radio Drive program (ABC 891, Grant Cameron) re older women having children in Australia. 10/1/07 interviewed on Canberra radio 2CC with Mike Jeffries re Catholic Hospitals and IVF 10/1/07 quoted in "The Australian" 10/1/07 re Catholic Hospitals and IVF. Adam Creswell journalist 2006 Quoted in "The Advertiser" 30/11/06 re older women turning to IVF and single embryo implants. 7/11/06 ABC Radio National re surrogacy laws in Australia. 7/11/06 Channel 10 TV news re surrogacy laws in Australia. 7/11/06 ABC Channel 2 news re surrogacy laws in Australia. 6/10/06 ABC TV program Stateline, profiling RCRH and speaking about DNA damage in male sperm

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9/10/06 Channel 9 TV News re PCOS 10/10/06 ABC Radio re opening of redevelopment of Discipline of O&G and RCRH in University of Adelaide 30/9/06 The Advertiser. Quoted re obesity and infertility. 9/9/06 The Advertiser. Quoted re a hormone discovery related to women with PCOS. 2 June 2006. Interviewed by ABC News re acupuncture and IVF.0 17/3/06 Interviewed on SAFM Radio regarding freezing eggs and the Egg Timer Test 9/3/06 Quoted in the Sydney Morning Herald re "Icy Reception" ­ marketing frozen eggs to single women. Journalist Danielle Teutsch. 3/3/06 Rob Norman was quoted in the Medical Observer regarding Twins and Single Embryo Transfers. Interviewed on ABC World, ABC radio, Channel 9 News and Channel 10 News on 27/1/06 regarding the late Prof John Kerin. Independent Weekly ­ article "SA's innovative IVF research continues" 12/2/06, page 15. 2005 The Advertiser ­ "Abide by Mother Nature's Limit" 20/1/2005 Pg 19 Radio ABC Darwin ­ Interview re Gay Women and IVF 9/3/05 Channel 7 News ­ featured re PCOS on 16/3/05 The Advertiser ­ "Motherhood's golden age" 26/4/05 Pg 9 The Advertiser ­ quoted regarding Medicare coverage on IVF on 27/4/05 The Advertiser ­ "IVF boss says PM harming families" 27/4/05 Pg 9 The Advertiser ­ "Designer babies created by IVF screening" 3/5/05 Pg 9 News in Science ­ "The pill boosts sports performance" 4/5/05 The Advertiser ­ "Pill lifts aerobic power in women" 6/5/05 Pg 3 Channel 7 TV ­ Interview with Lee McClusky regarding birth of the first baby using frozen eggs 16/6/05. The Advertiser ­ "Miracle baby gives hope to women" 18/6/05 Pg 1 & 12 ABC Radio Adelaide ­ regarding Medicare funding for IVF 4/7/05 The Independent Weekly newspaper ­ Rob Norman "SA universities steer IVF progress" 10/7/05 The Advertiser 3/8/05 ­ Rob Norman announced as a finalist for Research and Leadership in the Premier's Science Awards. The Advertiser 10/9/05 ­ Rob Norman quoted re transferring some genetic material from the fertilised egg of one woman into an egg from another. ABC Radio Darwin, interview re donor sperm and legal aspects of paternity. 13/10/05

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Channel 7 News ­ Rob Norman and Theresa Hickey appeared regarding PCOS on 4/11/05 Radio interview on 5DU Dubbo regarding prevention of multiple gestation in IVF on 28/11/05. Interviewed re SkyTV News re prevention of multiple gestation in IVF on 28/11/05. Quoted in The Age on 28/11/05 re prevention of multiple gestation in IVF. Quoted in The Australian on 28/11/05 on prevention of multiple gestation in IVF. Interviewed by Sydney Morning Herald on 28/11/05 re prevention of multiple gestation in IVF. Other TV and press interviews with unknown media at Multiple Births meeting in Melbourne sponsored by Bertarelli Foundation on 28/11/05. 06/12/05 Interviewed by ABC Radio 891 re 49 year old woman who has become pregnant using a natural therapy program. 2004 Speaker on a Rural Health Education Foundation (and Jean Hailes Foundation) satellite television program, providing dynamic and interactive distance learning professional development programs for GP's. Oct 04 Channel 10 Television with Jane Reilly re PCOS. 7/4/04 Radio Adelaide Interview re Research Centre 5/4/04 Channel 7 Television Interview re Optifast Trial 1/10/04 ABC Television ­ interview at Repromed 21/9/04 The Advertiser ­ "IVF Babies now bigger, stronger healthier" 1/10/04 Sunday Mail ­ "Selling of donor eggs" 5/9/04 Financial Review ­ Commercialisation 30/8/04 Public Forum on PCOS at Women's & Children's Hospital 14/4/04 Channel 10 Television regarding PCOS 13/4/04 The Advertiser ­ "PGD screening for disorders as cystic fibrosis, haemophilia and muscular dystrophy" 15/3/04 Sunday Mail ­ "Doctors want laws changed" legalising altruistic surrogacy 19/9/04

International Visitors:

Many visitors over past two decades

Previous, Current and Proposed Research Experience

I performed my research as a first year medical student during the holiday vacation period. I subsequently did an inter-collated BSc Honours course at Birmingham University where I achieved First Class Honours. From 1988 onwards, I have been involved in research virtually full time, specialising in the areas of reproduction, endocrinology, nutrition, assisted reproductive technology and clinical applications of reproductive biology. I've led small and large research teams and have been recognised

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for research leadership as evidenced by the Australasian Menopause Society Award in 2001 and the Premier's Science Excellence Award in 2005 and 2006.

Commercial Translation of Research

I've been involved in two companies set up by the Department of Obstetrics and Gynaecology in Adelaide. The first was a clinical reproductive medicine company, Repromed, in which I have been involved in a leadership role for more than fifteen years. I was initially Deputy Head and subsequently Head, of Repromed at a time when the company grew to be one of the most prominent and influential in Australia. The aim of the company was to provide clinical reproduction medicine services, returning the profits to research in reproductive medicine. The second company was Reproductive Health Sciences, which was set up from pioneering work on chromosomal analysis on single cells, initially from an embryo and subsequently from placenta. Members of my Research Centre have registered many patents and have many consultancies with industry.

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RESEARCH INTERESTS: Polycystic Ovary Syndrome Ovarian Physiology and Reproductive Endocrinology Assisted Reproduction Gonadotrophin Structure and Function Cytokines & Reproductive Function

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Publications

Publications 2008 Book Chapters 2008 Norman RJ, Ruifrok AE, Moran LJ, Robker RL. Recommended Therapies for Metabolic Defects in Polycystic Ovary Syndrome. Contemporary Endocrinology; Polycystic Ovary Syndrome, Chapter 16 pp 259-279. 2008 Refereed Journal Articles 2008 Rajendran S, Willoughby S, Chan A, Liberts E, Herestzyn T, Saha M, Marber M, Norman RJ, Horowitz JD. Polycystic Ovary Syndrome is Associated with Severe Platelet and Endothelial dysfunction in Both Obese and Lean Subjects. Atherosclerosis. In Press Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale H, Futterweit W, Janssen O, Legro R, Norman RJ, Taylor A, Witchel F. (Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PDOS Society) The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertility and Sterility June 2008 In press De Medeiros SF, Norman RJ. Human choriogonadotrophin protein core aqnd sugar branches heterogeneity: basic and clinical insights. Human Reprod Update Oct 2008 (in press) Nieuwenuis-Ruifrok AE, Kuchenbecker WK, Hoek A, Middleton P, Norman RJ. Insulin sensitizing drugs for weight loss in women of reproductive age who are overweight or obese: systematic review and meta-analysis. Human Reprod Update Oct 15 2008 (In press) Davis SR, Stuckey BG, Norman RJ, Papalia MA, Drillich A, Bell RJ. Effects of the route of estrogen administration on insulinlike growth factor-I, IGF binding protein-3, and insulin resistance in healthy postmenopausal women: results from a randomized, controlled study. Menopause 2008 Sep 17 (In press) Thomson RL, Buckley JD, Noakes M, Clifton PM, Norman RJ, Brinkworth GD. The effect of a hypocaloric diet with and without exercise training on body composition, cardiometabolic risk profile, and reproductive function in overweight and obese women with polycystic ovary syndrome. J Clin Endocrinol Metab 2008 Sep: 93(9):3373-80 Cummings S, Ettinger B, Delmas P, Kenemans P, Stathopoulos V, Vieerweij P, Mol-Arts M, Kloosterboer L, Mosca L, Christiansen C, Bilezikian J, Kerzberg E, Johnson S, Zanchetta J, Grobbee D, Seifert W, Eastell R et al (R J Norman co-author) The effects of Tibolone in Older Postmenopausal Women. The New England Journal of Medicine, August 08, 359:697-708 Minge CE, Bennett BD, Norman RJ, Robker RL. Peroxisome Proliferator-Activated Receptor ­ Agonist Rosiglitazone Reverses the Adverse Effects of Diet-Induced Obesity on Oocyte Quality. Endocrinology, May 2008, 149(5):2646-2656 Norman RJ, Chura LR, Robker RL. Effects of obesity on assisted reproductive technology outcomes. Fertil Steril 2008 Jun; 89(6): 15611-2 Davis S, Papalia M, Norman RJ et al. Safety and Efficacy of a Testosterone Metered-Dose Transdermal Spray for Treating Decreased Sexual Satisfaction in Premenopausal Women. Annals of Internal Medicine, April 2008, Volume 148, No 8, 569-577

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Nijland EA, Eeijmar Schultz WC, Nathorst-Boos J, Helmond FA, Van Lunsen RH, Palacios S, Norman RJ, Mulder RJ, Davis SR, LISA study investigators. Tibolone and transdermal E2/NETA for the treatment of female sexual dysfunction in naturally menopausal women: results of a randomized active-controlled trial. J Sex Med 2008 Mar;5(3):646-56 Zain MM, Jamaluddin R, Ibrahim A, Norman RJ Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction, achievement of pregnancy, and live birth in Asian women with polycystic ovary syndrome: a randomized controlled trial. Fertil Steril 2008 Mar 3 (in press) Thessaloniki ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Consensus on infertility treatment related to polycystic ovary syndrome. Fertil Steril. 2008 Mar;89(3):505-22. Moran LJ, Noakes M, Clifton PM, Norman RJ, Fenech MF. Genome instability is increased in lymphocytes of women with polycystic ovary syndrome and is correlated with insulin resistance. Mutat Res. 2008 Mar 1;639(1-2):55-63. Moran LJ, Brinkworth GD, Norman RJ. Dietary therapy in polycystic ovary syndrome. Semin Reprod Med. 2008 Jan;26(1):85-92. Minge CE, Robker RL, Norman RJ "PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility", PPAR Research, vol 2008 Article ID 243791, 19 pages 2008 doi:10.1155/2008/243791 Books 2007 Kovacs G, Norman RJ. Polycystic Ovary Syndrome Second Edition (Editor and Co-author). Cambridge Press. Book Chapters 2007 Norman RJ and Moran LJ. Weight, fertility and management approaches. Chapter 4, pages 24-35. Advances in Fertility Studies and Reproductive Medicine ­ IFFS 2007. Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic Ovary Syndrome. Lancet 2007 Aug 25;370(9588):685-97. Review Norman RJ, Moran L. Lifestyle factors in the etiology and management of polycystic ovary syndrome. Chapter 9, pages 121-139. Cambridge University Press, Polycystic Ovary Syndrome Second Edition 2007 Warnes GM, Norman RJ. Quality management systems in ART: are they really needed? An Australian clinic's experience. Best Practice & Research Clinical Obstetrics & Gynaecology Volume 21, Issue 1, February 2007, Pages 41-55 Norman RJ. Preface to Best Practice & Research Clinical Obstetrics & Gynaecology 2007 Feb;21(1):3. Conference Proceedings IFFS 2007, Advances in Fertility Studies and Reproductive Medicine. Editors TF Kruger, Z Van Der Spuy, RD Kempers. RJ Norman and L Moran Weight, fertility and;management approaches. Publication Norman RJ. Leadership. Luke's Journal of Christian Medicine & Dentistry Vol 12 No. 2 June 2007, pages 12-16

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Refereed Journal Articles 2007 Homan GF, Davies M, Norman R. The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review. Human Reproduction Update, Vol.13, No. 3 pp 209-223, 2007 Lim SS, Noakes M, Norman RJ. Dietary effects on fertility treatment and pregnancy outcomes. Curr Opin Endocrinol Diabetes Obes. 2007 Dec14(6):465-9) Galletly C, Moran L, Noakes M, Clifton P, Tomlinson L, Norman RJ. Psychological benefits of a high-protein, low carbohydrate diet in obese women with polycystic ovary syndrome ­ A pilot study. Appetite, Vol.ume 49, Issue 3, November 2007 Pages 590-593 Hart R, Sloboda DM, Doherty DA, Norman R et al (2007) The effect of intrauterine exposure to maternal adrogens on the incidence of Polycystic Ovarian syndrome in a cohort of Australian adolescents ­ The Raine cohort Early Human Development, 83: S54-S54 Suppl. 1 Oct 2007 Norman RJ, Hickey T, Moran L (2007) Genetic/epigenetic and environmental origins of PCOS. Early Human Development, 83: S43-S44 Suppl. 1 Oct 2007 Sturgeon C, Berger P, Birken S, Norman R et al (2007) HCG standardization and quality control. Tumor Biology 28: 15-15 Suppl. 1 2007 De Lacey S, Davies M, Homan G, Briggs N, Norman RJ. Factors and perceptions that influence women's decisions to have a single embryo transferred. RBM Online Vol 15.No.5 2007 526-531 De Lacey S, Davies M, Homan, G, Norman RJ et al (2007) Factors and perceptions that influence women's decisions to have a single embryo transferred. Australian & New Zealand Journal of Obstetrics and Gynaecology, 47: A8-A8 Suppl. 1 Sep 2007 Homan G, Norman R, (2007) A "snapshot" of couple's perception of how modifiable lifestyle choices might affect fertility. Australian and New Zealand Journal of Obstetrics and Gynaecology, 47: A14-A14 Suppl. 1 Sep 2007 Norman RJ, (2007) Empty cots and silent spring in an age of plenty ­ What our lifestyle is doing to our reproductive health. Australian and New Zealand Journal of Obstetrics and Gynaecology, 47:A22-A22 Suppl 1 Sep 2007 Dabadghao P, Roberts BJ, Wang J, Davies MJ, Norman RJ. Glucose tolerance abnormalities in Australian women with polycystic ovary syndrome. Med J Aust. 2007 Sep 17;187(6):328-31. Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic Ovary syndrome. Lancet 2007 Aug 25;370(9588):685-97. Review Moran LJ, Noakes M, Clifton PM, Norman RJ. The use of Anti-Mullerian hormone in predicting menstrual response following weight loss in overweight women with Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2007 Oct;92(10): 3796-802 Moran LJ, Noakes M, Clifton PM, Wittert GA, Belobrajdic DP, Norman RJ. Creactive protein before and after weight loss in overweight women with and without polycystic ovary syndrome. J Clin Endocrinol Metab. 2007 Aug;92(8):2944-51

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Tian L, Shen H, Lu Q, Norman RJ, Wang J. Insulin resistance increases the risk of spontaneous abortion after assisted reproduction technology treatment. J Clin Endocrinol Metab. 2007 Apr;92(4):1430-3. Stankiewicz M, Smith C, Alvino H, Norman R. The use of complementary medicine and therapies by patients attending a reproductive medicine unit in South Australia: A prospective survey. The Australian and New Zealand Journal of Obstetrics and Gynaecology, Vol 47, Number 2, April 2007 Pg 145-149 Wu R, Fumii S, Ryan NK, Van der Hoek KH, Jasper MJ, Sini I, Robertson SA, Robker RL, Norman RJ. Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome. Hum Reprod 2007 Feb;22(2):527535. Norman RJ. Preface. Best Practice & Research Clinical Obstetrics & Gynaecology , Volume 21, Issue 1, February 2007, Page 3. Lim SS, Clifton PM, Noakes M, Norman RJ. Obesity management in women with polycystic ovary syndrome. Women's Health Journal Jan 2007 Vol. 3 No. 1

Book Chapters 2006 Ferrera L (Editor) Focus on Body Mass Index and Health Research (Chapter 3 ­ Wang J, Dabadghao P, Norman RJ ­ The BMI as a Risk Indicator for Human Reproductive Health). Nova Science Publishers Inc, New York Kovacs G (Editor) Norman RJ, Clark AM. Polycystic Ovary Syndrome (Chapter 9 ­ Lifestyle factors in the aetiology and management of Polycystic ovary syndrome) Cambridge Unviersity Press Refereed Journal Articles 2006 Stankiewicz M, Norman RJ Diagnosis and management of polycystic ovary syndrome ­ A practical guide Drugs 2006 66(7): 903-912. Norman RJ, Davies M, Wang J, Lane M. Prevention of multiple gestation in IVF: Introduction to Theme. Aus NZ J Obstet Gynaecol. 2006 Dec; 46 Suppl:S14-6. Norman RJ, Homan G, Moran L, Noakes M. Lifestyle choices, diet, and insulin sensitizers in polycystic ovary syndrome. Endocrine 2006 Aug 30(1): 35-43 Brinkworth GD, Noakes M, Moran LJ, Norman R, Clifton PM. Flow-mediated dilatation in overweight and obese women with polycystic ovary syndrome. RCOG 2006 BJOG An International Journal of Obstetrics and Gynaecology. Nov 2006 113(11): 1308-1314 ` Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF. Position statement: /Criteria for Defining Polycystic Ovary Syndrome as a predominantly hyperandrogenic syndrome: an androgen Excess Society Guideline. J Clin Endocrinol Metab. 2006 Nov; 91(11):4237-45. Smith C, Coyle M, Norman RJ. Influence of acupuncture stimulation on pregnancy rates for women undergoing embryo transfer. Fertility and Sterility Vol 85, No. 5. May 2006, 1352-8.

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Moran L, Brinkworth G, Noakes M, Norman RJ. Symposium: Diet, Nutrition and Exercise in Reproduction ­ Effects of lifestyle modification in polycystic ovarian syndrome. RBM Online 2006;12(5):569-578. Hart R, Norman RJ. Polycystic ovarian syndrome ­ prognosis and outcomes. Best Practice & Research Clinical Obs & Gynae Vol 20 No 5 pp 751-778 2006 Moran LJ, Noakes M, Clifton PM, Wittert GA, Williams G, Norman RJ. 2006, Short term meal replacements followed by dietary macronutrient restriction enhances weight loss in Polycystic Ovary Syndrome. The American Journal of Clinical Nutrition; 2006 Jul;84(1):77-87 Norman RJ. Symposium: Diet, Nutrition and Exercise in Reproduction. RBM Online 2006;12(5):524-525 Lord J, Norman RJ. Obesity, polycystic ovary syndrome, infertility treatment. British Medical Journal 2006; 332:609 Crosignani PG, Norman RJ et al. Nutrition and Reproduction in Women. Human Reproduction Update 2006 12(2) 193-207. Hickey T, Norman RJ. Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism (JCEM). Jul;91(7):2789-91 Tsagareli V, Noakes M, Norman RJ. Effect of a very low-calorie diet on in vitro fertilisation outcomes. . Fertility and Sterility 2006 Jul;86(1):227-229. Wang J, Lane M, Norman RJ. Reducing multiple pregnancy from assisted reproduction treatment: educating patients and medical staff. MJA Vol 184, No. 4 pp 180-181, Feb 2006 Rombauts L, Healy D, Norman RJ. A comparative randomised trial to assess the impact of oral contraceptive pre-treatment on follicular growth and hormone profiles in GnRH antagonisttreated patients. Human Reproduction Vol 21, No.1 pp 95-103, 2006. Minge C, Ryan N, Van Der Hoek K, Robker R, Norman RJ. Troglitazone Regulates Peroxisome Proliferator-Activated Receptors and Inducible Nitric Oxide Synthase in Murine Ovarian Macrophages. Biology of reproduction 74(1), 153-160 (2006) Book Chapters 2005 Abnormal Laboratory Results, edited by Geoffrey Kellerman. R J Norman, chapter 22 Fertility Testing. Pp 152-157 Invited Articles 2005 Medical Observer, June 2005. Oligomenorrhea and mild hyper-prolactinaemia 2005 Mitchell M, Armstrong DT, Robker RL, Norman RJ. Adipokines: implications for female fertility And obesity. Reproduction Review 2005 Nov, 130(S); S83-97

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Teede HJ, Meyer C, Norman RJ. Insulin-sensitisers in the treatment of polycystic ovary syndrome. Expert Opin Pharmacother. 2005 Nov;6(14):2419-27. Review Norman RJ, MacLennan AH. Current status of hormone therapy and breast cancer. Human Reprod Update, Vol 11, No. 6.pp 541-543, 2005 Norman RJ, de Lacey s, Wang JX. Recombinant or urinary gonadotrophins ­ an Australian perspective. RBM Online 2005 Vol 11 No 5, 542-543 Davies MJ, Delacey SL, Norman RJ. Towards less confusing terminology in reproductive medicine. Hum Reprod. 2005 Vol 20, No.10 pp 2669-2671 Hickey TE, Marrocco DL, Amato F, Ritter LJ, Norman RJ, Gilchrist RB, Armstrong DT. Androgens Augment the Mitogenic Effects of Oocyte-Secreted Factors and Growth Differentiation Factor 9 on Porcine Granulosa Cells. Biol Reprod. 2005 Jun 22 73:825-832 Redman L, Scroop G, Westlander G, Norman R. Effect of a synthetic progestin on the exercise status of young sedentary women. The Journal of Clinical Endocrinology & Metabolism. 90(7):3830-3837. Bristow A, Berger P, Bidart J, Birken S, Norman R, Stenman U, Sturgeon C. Establishment, Value Assignment and Characterization of New WHO Reference Reagents for six Molecular Forms of Human Chorionic Gonadotropin. 2005 Clinical Chemistry 51:1 177-182 Cussons A, Stuckey B, Walsh J, Burke V, Norman R. Polycystic ovarian syndrome : marked differences between endocrinologists and gynaecologists in diagnosis and management. Clinical Endocrinology 2005; 62:289-295.

2004 Moran LJ, Noakes M, Clifton PM, Wittert G, Norman RJ. Short term energy restriction (using meal replacements) improves reproductive parameters in polycystic ovary syndrome. Asia Pac J Clin Nutr. 2004; 13(Suppl):S88 Moran LJ, Norman RJ. Understanding and managing disturbances in insulin metabolism and body weight in women with polycystic ovary syndrome. Best Pract Res Clin Obstet Gynaecol. 2004 Oct;18(5):719-36. Review Norman RJ. Editorial: Metformin ­ comparison with other therapies in ovulation inductin in polycystic ovary syndrome. J Clin Endocrinol Metab. 2004 Oct; 89(10):4797-800. Muller T, Gromoll J, Simula AP, Norman R, Sandhowe-Klaverkamp R, Simoni M. The carboxyterminal peptide of chorionic gonadotrophin facilitates activation of the marmoset LH receptor. Exp Clin Endocrinol Diabetes 2004;112(10):574-9. Bonello N, Jasper MJ, Norman RJ. Periovulatory expression of intercellular adhesion molecule1 in the rat ovary. Biol Reprod 2004;71(4):1384-90. Dare MR, Crowther CA, Dodd JM, Norman RJ. Single or multiple embryo transfer following in vitro fertilisation for improved neonatal outcome: A systematic review of the literature. Aust N Z J Obstet Gynaecol 2004;44(4):283-91. Norman RJ, Noakes M, Wu R, Davies MJ, Moran L, Wang JX. Improving performance in overweight/obese women with effective weight management. Hum Reprod Update. 2004 MayJun;10(3):267-80.

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Davies MJ, Wang JX, Norman RJ. What is the most relevant standard of success in assisted reproduction? Assessing the BESST index for reproduction treatment. Hum Reprod 2004;19(5):1049-51. de Lacey S, Norman RJ. What should we do with donated embryos that may be genetically affected? Hum Reprod 2004;19(5):1065-8. Hickey TE, Marrocco DL, Gilchrist RB, Norman RJ, Armstrong DT. Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles. Biol Reprod 2004;71(1):45-52. Moran LJ, Noakes M, Clifton PM, Wittert GA, Tomlinson L, Galletly C, Norman RJ, et al. Ghrelin and measures of satiety are altered in polycystic ovary syndrome but not differentially affected by diet composition. J Clin Endocrinol Metab 2004;89(7):3337-44. Muller T, Simoni M, Pekel E, Luetjens CM, Chandolia R, Amato F, Norman RJ, Luscombe N. Chorionic gonadotrophin beta subunit mRNA but not luteinising hormone beta subunit mRNA is expressed in the pituitary of the common marmoset (Callithrix jacchus). J Mol Endocrinol 2004;32(1):115-28. Norman RJ. Metformin ­ comparison with other therapies in ovulation induction in polycystic ovary syndrome. J Clin Endocrinol Metab 2004; 71(4):1384-90. Norman RJ, et al. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertility and Sterility 2004;81(1):19-25. Norman RJ, et al. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). European Society of Human Reproduction and Embryology. Human Reproduction 2004;19(1):41-47. Norman RJ, Hickey T, Moran L, Boyle J, Wang J, Davies M. Polycystic ovary syndrome diagnosis and etiology. In: Daya S H, R and Kempers, R, editor. Advances in Fertility and Reproductive Medicine. Montreal: Elsevier, 2004:225-32. Norman RJ, Wang JX, Hague W. Should we continue or stop insulin sensitizing drugs during pregnancy? Curr Opin Obstet Gynecol 2004;16(3):245-250. Norman RJ, Wu R. The potential danger of COX-2 inhibitors. Fertil Steril 2004;81(3):493-4. Norman RJ, Wu R, Stankiewicz MT. 4: Polycystic ovary syndrome. Med J Aust 2004;180(3):132-7. Wang J, Norman RJ. Risk factors for the deterioration of glucose metabolism in polycystic ovary syndrome. Reproductive Biomedicine Online 2004;9(2):201-204. Wang JX, Norman RJ, Wilcox AJ. Incidence of spontaneous abortion among pregnancies produced by assisted reproductive technology. Hum Reprod 2004;19(2):272-7. Wang JX, Warnes GW, Davies MJ, Norman RJ. Overweight infertile patients have a higher fecundity than normal-weight women undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertil Steril 2004;81(6):1710-2.

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Wu R, Van der Hoek KH, Ryan NK, Norman RJ, Robker RL. Macrophage contributions to ovarian function. Hum Reprod Update 2004;10(2):119-33. 2003 Birken S, Berger P, Bidart JM, Weber M, Bristow A, Norman RJ, et al. Preparation and characterization of new WHO reference reagents for human chorionic gonadotropin and metabolites. Clin Chem 2003;49(1):144-54. Hussey N, Norman RJ. Pre-Implantation genetic diagnosis. Hong Kong Medical Journal 2003;9(1):4-5. Lord JM, Flight IH, Norman RJ. Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome. Cochrane Database Syst Rev 2003(3):CD003053. Lord JM, Flight IH, Norman RJ. Metformin in polycystic ovary syndrome: systematic review and meta-analysis. Bmj 2003;327(7421):951-3. Magoffin DA, Duggal PS, Norman RJ. The role of leptin in polycystic ovary syndrome. In: Castracane Ha, editor. Leptin and Reproduction: Kluwer/Academic/Plenum Publishers, 2003:333-41. Moran LJ, Noakes M, Clifton PM, Tomlinson L, Norman RJ. Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003;88(2):812-9. Redman LM, Scroop GC, Norman RJ. Impact of menstrual cycle phase on the exercise status of young, sedentary women. Eur J Appl Physiol 2003;90(5-6):505-13. Ryan NK, Van der Hoek KH, Robertson SA, Norman RJ. Leptin and leptin receptor expression in the rat ovary. Endocrinology 2003;144(11):5006-13. Wang JX, Kwan M, Davies MJ, Kirby C, Judd S, Norman RJ. Risk of multiple pregnancy when infertility is treated with ovulation induction by gonadotropins. Fertil Steril 2003;80(3):664-5. Westlander G, Barry M, Petrucco O, Norman RJ. Different fertilization rates between immotile testicular spermatozoa and immotile ejaculated spermatozoa for ICSI in men with Kartagener's syndrome: case reports. Hum Reprod 2003;18(6):1286-8. 2002 Amato F, Warnes GM, Kirby CA, Norman RJ. Infertility caused by HCG autoantibody. J Clin Endocrinol Metab 2002;87(3):993-7. Bonello N, Norman RJ. Soluble adhesion molecules in serum throughout the menstrual cycle. Hum Reprod 2002;17(9):2272-8. Davies M, Norman RJ. Neurological sequelae in in-vitro fertilisation babies. Lancet 2002;360:717-19. Davies MJ, Norman RJ. Programming and reproductive functioning. Trends Endocrinol Metab 2002;13(9):386-92. Duggal PS, Ryan NK, Van der Hoek KH, Ritter LJ, Armstrong DT, Magoffin DA, Norman RJ, et al. Effects of leptin administration and feed restriction on thecal leucocytes in the preovulatory rat ovary and the effects of leptin on meiotic maturation, granulosa cell proliferation, steroid hormone and PGE2 release in cultured rat ovarian follicles. Reproduction 2002;123(6):891-8.

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Duggal PS, Weitsman SR, Magoffin DA, Norman RJ. Expression of the long (OB-RB) and short (OB-RA) forms of the leptin receptor throughout the oestrous cycle in the mature rat ovary. Reproduction 2002;123(6):899-905. Hickey T, Chandy A, Norman RJ. The androgen receptor CAG repeat polymorphism and Xchromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome. J Clin Endocrinol Metab 2002;87(1):161-5. Hickey T, Norman RJ. Polycystic ovary syndrome (PCOS): Gene and Environment. In: Remohi J, Pellicer A, Simon C, Navarro J, editors. Human Reproduction 11 Edition, 2002:161-69. Hickey T, Norman RJ. Molecular genetics of polycystic ovary syndrome. In: Pellicer CSA, editor. Cuadernos de Medicina Reproductiva, 2002:165-185. Hussey ND, Davis T, Hall JR, Barry MF, Draper R, Norman RJ, et al. Preimplantation genetic diagnosis for beta-thalassaemia using sequencing of single cell PCR products to detect mutations and polymorphic loci. Mol Hum Reprod 2002;8(12):1136-43. McDonald JA, Norman RJ. A randomized controlled trial of a soft double lumen embryo transfer catheter versus a firm single lumen catheter: significant improvements in pregnancy rates. Hum Reprod 2002;17(6):1502-6. Moran LJ, Norman RJ. The obese patient with infertility: a practical approach to diagnosis and treatment. Nutr Clin Care 2002;5(6):290-7. Norman RJ. Hyperandrogenaemia and the ovary. Mol Cell Endocrinol 2002;191(1):113-9. Norman RJ. Fertility Testing. Australian Prescriber 2002;25:38-40. Norman RJ. Obesity and Infertility. In: Hansotia M, Desai S, Parihar M, editors. Advanced Infertility and Management. New Delhi India: Jaypee Brothers Medical Publishers, 2002. Norman RJ, Davies M. Lifestyle factors and polycystic ovary syndrome. In: Chang RJ, Heindel A, Dunaif A, editors. Polycystic Ovary Syndrome. New York USA: Marcel Dekker Inc, 2002:30726. Norman RJ, Davies MJ, Lord J, Moran LJ. The role of lifestyle modification in polycystic ovary syndrome. Trends Endocrinol Metab 2002;13(6):251-7. Robson S, Norman RJ. The endocrine basis for spontaneous ovulation, ovulation induction and controlled super ovulation. In: Jacobs H, Sathanandan SM, editors. Practical Guide to Ovulation Induction. London: Imperial College Press of University of London, 2002. Ryan NK, Woodhouse CM, Van der Hoek KH, Gilchrist RB, Armstrong DT, Norman RJ. Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation. Biol Reprod 2002;66(5):1548-54. Wang JX, Davies MJ, Norman RJ. Obesity increases the risk of spontaneous abortion during infertility treatment. Obes Res 2002;10(6):551-4. Wang JX, Knottnerus AM, Schuit G, Norman RJ, Chan A, Dekker GA. Surgically obtained sperm, and risk of gestational hypertension and pre-eclampsia. Lancet 2002;359(9307):673-4. Wang JX, Norman RJ, Kristiansson P. The effect of various infertility treatments on the risk of preterm birth. Hum Reprod 2002;17(4):945-9.

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Winter E, Wang J, Davies MJ, Norman RJ. Early pregnancy loss following assisted reproductive technology treatment. Hum Reprod 2002;17(12):3220-3. 2001 Lok F, Norman RJ. Treatment of hyerandrogenism by loss of weight and insulin sensitisers. Gynaecology Forum 2001;6(3):22-30. Norman RJ. Reproductive consequences of COX-2 inhibition. Lancet 2001;358(9290):1287-8. Norman RJ. Obesity, polycystic ovary syndrome and anovulation--how are they interrelated? Curr Opin Obstet Gynecol 2001;13(3):323-7. Norman RJ. As many embryos as you like - one at a time. ACCESS National Newsletter 2001;8(20):3. Norman RJ, Kidson WJ, Cuneo RC, Zacharin MR. Metformin and intervention in polycystic ovary syndrome. Endocrine Society of Australia, the Australian Diabetes Society and the Australian Paediatric Endocrine Group. Med J Aust 2001;174(11):580-3. Norman RJ, Masters L, Milner CR, Wang JX, Davies MJ. Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome. Hum Reprod 2001;16(9):1995-8. Norman RJ, Milner CR, Groome NP, Robertson DM. Circulating follistatin concentrations are higher and activin concentrations are lower in polycystic ovarian syndrome. Hum Reprod 2001;16(4):668-72. Norman RJ, Moran L, Davies M. Nutritional aspects of polycystic ovary syndrome. Reproductive Medicine Review 2001;9(2):91-107. Robertson SA, Sjoblom C, Jasper MJ, Norman RJ, Seamark RF. Granulocyte-macrophage colony-stimulating factor promotes glucose transport and blastomere viability in murine preimplantation embryos. Biol Reprod 2001;64(4):1206-15. Tremellen K, Norman RJ. The effect of intercourse on pregnancy rates during assisted human reproduction - reply letter to editor. Hum Reprod 2001;16(9):2029. Wang JX, Davies MJ, Norman RJ. Polycystic ovarian syndrome and the risk of spontaneous abortion following assisted reproductive technology treatment. Hum Reprod 2001;16(12):2606-9. 2000 Duggal PS, Van Der Hoek KH, Milner CR, Ryan NK, Armstrong DT, Magoffin DA, Norman RJ, et al. The in vivo and in vitro effects of exogenous leptin on ovulation in the rat. Endocrinology 2000;141(6):1971-6. Gilchrist RB, Rowe DB, Ritter LJ, Robertson SA, Norman RJ, Armstrong DT. Effect of granulocyte-macrophage colony-stimulating factor deficiency on ovarian follicular cell function. J Reprod Fertil 2000;120(2):283-92. Gonzalez RR, Simon C, Caballero-Campo P, Norman RJ, Chardonnens D, Devoto L, et al. Leptin and reproduction. Hum Reprod Update 2000;6(3):290-300. Jasper MJ, Robertson SA, Van der Hoek KH, Bonello N, Brannstrom M, Norman RJ. Characterization of ovarian function in granulocyte-macrophage colony-stimulating factordeficient mice. Biol Reprod 2000;62(3):704-13.

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Li R, Norman RJ, Armstrong DT, Gilchrist RB. Oocyte-secreted factor(s) determine functional differences between bovine mural granulosa cells and cumulus cells. Biol Reprod 2000;63(3):839-45. Norman RJ. Genetic & Environmental Origins of Polycystic Ovary Syndrome. In: Salamonsen LA, editor. Hormones and Women's Health: The Reproductive Years: Harwood Academic Press, 2000:71-81. Norman RJ. Weighing up the risks. ORGYN 2000;4:7-9. Norman RJ. Obesity and Reproductive Disorders. The Role of Practical Lifestyle Changes. The Female Patient 2000;25:15-18. Norman RJ, Buchholz MM, Somogyi AA, Amato F. hCGbeta core fragment is a metabolite of hCG: evidence from infusion of recombinant hCG. J Endocrinol 2000;164(3):299-305. Norman RJ, Flight IH, Rees MC. Oestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distribution. Cochrane Database Syst Rev 2000(2):CD001018. Norman RJ, McVeigh E. Polycystic ovary syndrome and implications for the menopause. Climateric 2000;2:141-43. Tremellen KP, Valbuena D, Landeras J, Ballesteros A, Martinez J, Mendoza S, Norman RJ, et al. The effect of intercourse on pregnancy rates during assisted human reproduction. Hum Reprod 2000;15(12):2653-8. Van der Hoek KH, Maddocks S, Woodhouse CM, van Rooijen N, Robertson SA, Norman RJ. Intrabursal injection of clodronate liposomes causes macrophage depletion and inhibits ovulation in the mouse ovary. Biol Reprod 2000;62(4):1059-66. Wang JX, Davies M, Norman RJ. Body mass and probability of pregnancy during assisted reproduction treatment: retrospective study. Bmj 2000;321(7272):1320-1. 1999 Bacich DJ, Earl CR, O'Keefe DS, Norman RJ, Rodgers RJ. Characterization of the translated products of the alternatively spliced luteinizing hormone receptor in the ovine ovary throughout the oestrous cycle. Mol Cell Endocrinol 1999;147(1-2):113-24. Brannstrom M, Friden B, Jasper M, Norman RJ. Variations in peripheral blood levels of immunoreactive tumor necrosis factor a (TNFa) throughout the menstrual cycle and its secretion from the human corpus luteum. Eur J Obstet Gynecol Reprod Biol 1999;83:213-217. Flaherty SP, Payne D, Norman RJ. What is the best strategy for using embryos and presenting results in assisted reproductive technology? A strategy for valid comparisons of results. J Assist Reprod Genet 1999;16(9):471-3. Huber-Buchholz MM, Carey DG, Norman RJ. Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: role of insulin sensitivity and luteinizing hormone. J Clin Endocrinol Metab 1999;84(4):1470-4. Milner CR, Craig JE, Hussey ND, Norman RJ. No association between the -308 polymorphism in the tumour necrosis factor alpha (TNFalpha) promoter region and polycystic ovaries. Mol Hum Reprod 1999;5(1):5-9.

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Norman RJ, Bonello N, Jasper M, Van der Hoek KH, Shinetugs B, Robertson SA. The leukocyte-cytokine network: an essential component of normal and abnormal ovarian function? In ovarian hyperstimulation syndrome, pathology, prevention and treatment. In: Pellicer A, Simon C, Bonnilla-Musoles F, Remohi J, editors. Serono Fertility Series, 1999:1-15. Norman RJ, McVeigh E. Polycystic ovary syndrome and implications for the menopause. Climacteric 1999;2(2):141-3. Phillips DI, Fall CH, Cooper C, Norman RJ, Robinson JS, Owens PC. Size at birth and plasma leptin concentrations in adult life. Int J Obes Relat Metab Disord 1999;23(10):1025-9. Shinetugs B, Runesson E, Bonello NP, Brannstrom M, Norman RJ. Colony stimulating factor-1 concentrations in blood and follicular fluid during the human menstrual cycle and ovarian stimulation: possible role in the ovulatory process. Hum Reprod 1999;14(5):1302-6. Urbanek M, Legro RS, Driscoll DA, Azziz R, Ehrmann DA, Norman RJ, et al. Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin. Proc Natl Acad Sci U S A 1999;96(15):8573-8. 1998 Amato F, Simula AP, Gameau LJ, Norman RJ. Expression, characterisation and immunoassay of recombinant marmoset chorionic gonadotrophin dimer and beta-subunit. J Endocrinol 1998;159(1):141-51. Clark AM, Thornley B, Tomlinson L, Galletley C, Norman RJ. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Hum Reprod 1998;13(6):1502-5. Norman RJ. Life Decisions. Life Science 1998;10:12-14. Norman RJ. Weight gain in midlife. Change of Life... Time for Change A report from the 1st Australiasian Menopause Society Congress 1998. Norman RJ. Genes and environment in human reproductive disorders. Papers from a symposium held on 30 Nov - 1 Dec 1997. Reproduction, Fertility and Development 1998;10(1). Norman RJ. Hormones, Well-Being and Fertility. Turner Syndrome Assoc of Aust Ltd Newsletter Dec 1998. Norman RJ, Bonello N, Jasper M, Van der Hoek KH. Leukocytes: Essential cells in ovarian function and ovulation. Reprod Med Review 1998;6(2):97-111. Norman RJ, Clark AM. Obesity and reproductive disorders: a review. Reprod Fertil Dev 1998;10(1):55-63. Norman RJ, McDonald JA. Polycystic Ovary Syndrome. Current Therapeutics 1998;39:17-21. Phiilipson G, Norman RJ. The normal menstrual cycle; changes throughout life. Estrogens & Progestogens in Clinical Practice. First Edition ed, 1998:Chapter 11 105-118. Van der Hoek KH, Woodhouse CM, Brannstrom M, Norman RJ. Effects of interleukin (IL)-6 on luteinizing hormone- and IL-1beta-induced ovulation and steroidogenesis in the rat ovary. Biol Reprod 1998;58(5):1266-71. 1997

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Chapman IM, Wittert GA, Norman RJ. Circulating leptin concentrations in polycystic ovary syndrome: relation to anthropometric and metabolic parameters. Clin Endocrinol 1997;46:175181. Fuh, KW, Wang X, Tai A, Wong I, Norman RJ. Intrauterine insemination: Effect of the temporal relationship between the LH surge, hCG administration and insemination on pregnancy rates. Hum Reprod 1997;12:2162-2166 Hoy WE, Norman RJ, Hayhurst BG, Pugsley DJ. A health profile of adults in a Northern Territory Aboriginal community, with an emphasis on preventable morbidities. Australian & New Zealand Journal of Public Health. 1997;21: 121-126. Norman RJ. Management of the early menopause. Changes December 1997 (unrefereed) Norman RJ. Clinical chemistry and the new assisted reproductive technologies. Clin. Biochem Revs. 1997;18: 3019 Norman RJ, Huber-Buchholz MM, Hague WM. Genetic and environmental origins of polycystic ovary syndrome. Contemporary Reviews in Obst & Gyn June 1997;10:141-149. Wang LJ, Brannstrom M, Ke-Hui C, Simula AP, Hart RP, Maddocks S, Norman RJ. Localization of Gene Expression of Interleukin-1 Receptor and Interleukin-1 Receptor Antagonist in the Rat Ovary. J Endocrinology, 1997;152:11-17. 1996 Bonello N, McKie, K, Jasper M, Andrew L, Ross N, Braybon E, Brannstrom M, Norman RJ. Inhibition of Nitric Oxide: Effects on interleukin-beta-enhanced ovulation rate, steroid hormones, and ovarian leukocyte distribution at ovulation in the rat. Biol Reprod 1996;54(2): 436-45. Hoy WE, McFarlane R, Pugsley DJ, Norman R, Mathews JD. Markers for cardiovascular and renal morbidity: expectations for an intervention programme in an Australian Aboriginal community. Clinical & Experimental Pharmacology & Physiology 1996; 23:S33-37. Jasper MJ, Brannstrom M, Olofsson JI, Petrucco OM, Mason H, Robertson SA, Norman RJ. Granulocyte-macrophage colony-stimulating factor: presence in human follicular fluid, protein secretion and mRNA expression by ovarian cells. Mol Hum Reprod 1996;2(8):555-562. Latimer J, Norman RJ. Hormone replacement therapy: some questions answered. Modern Medicine CME January 12-21 1996. Norman RJ. New concepts in polycystic ovary syndrome 1996-97. RACOG Resource Manual, Vol 5, Dec 1996. Norman RJ. What is polycystic ovary syndrome?. The Newsletter of Gynaecological Care, October 1996. Norman RJ, Bonello N, Jasper M, Wang LJ, Brannstrom M. Immune-endocrine interactions during ovulation. Singapore J of Obst & Gynae 1996;27(1)25-31. Norman RJ, Brannstrom M. Cytokines in the ovary: pathophysiology and potential for pharmacological intervention. Pharmacology & Therapeutics 1996;69:219-236. Norman RJ. The indications for, and appropriate use of testosterone in hormone replacement therapy. A forum conducted 6th Dec, 1994 by Adelaide & Dale Street Women's Health Centres, published April 1996. Norman RJ, Masters S, Hague W. Hyperinsulinemia is common in family members of women with polycystic ovary syndrome. Fertil Steril 66 1996;6:942-947.

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1995 Brannstrom M, Bonello N, Norman RJ, Robertson SA. Reduction of ovulation rate in the rat by administration of neutrophil-depleting monoclonal antibody J Reprod Immunol 1995;29-265.270. Brannstrom M, Bonello N, Wang LJ, Norman RJ. Effects of tumor necrosis factor (TNF) on ovulation in the rat ovary. Reprod Fertil Develop 1995;7(1):67-73. Bonello NP, Norman RJ, Brannstrom M. Interleukin-1 inhibits luteinizing hormone-induced plasminogen activator activity in rat preovulatory follicles in vitro. Endocrine 1995;3:49-54. Buck R, Moodley J, Norman RJ. Is the human chorionic gonadotropin secreted by ectopic trophoblast different from that in normal intrauterine pregnancies? Fertil. Steril. 1995;64:724279. Clark AM, Ledger W, Galletly C, Tomlinson L, Blaney F, Wang X, Norman RJ. Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women. Hum Reprod 1995;10:2705-2712. Jasper M, Norman RJ. Immunoactive interleukin-1 and tumour necrosis factor- in thecal, stromal and granulosa cell cultures from normal and polycystic ovaries. Hum. Reprod. 1995;10:1352-1354. Lopata A, Berka J, Simula A, Norman R, Otani T. Differential distribution of mRNA for the and -subunits of chorionic gonadotrophin in the implantation stage blastocyst of the marmoset monkey. Placenta 1995;16:335-346. Ngan HYS, Yeung WSB, Cheng GTS, Wong LC, de Medeiros SF, Norman RJ, Ma HK. Problems in the use of urinary hCG-beta-core as a tumor marker in gynecologic cancer. Int J Gynecol Cancer 1995;5:15-19. Norman RJ, Mahabeer S, Masters S. Ethnic difference in insulin and glucose response to glucose between Caucasian and Indian women with polycystic ovary syndrome. Fertil Steril 1995;63:58-62. Norman RJ, Masters S, Hague WM, Beng C, Pannall P, Wang X. Metabolic approaches to the subclassification of polycystic ovary syndrome. Fertil Steril 1995;63:329-335. Norman RJ, Hague WM, Masters SC, Wang XJ. Subjects with polycystic ovaries without hyperandrogenaemia exhibit similar disturbances in insulin and lipid profiles as those with polycystic ovary syndrome. Hum Reprod 1995;10:2258-2261. Simula AP, Amato F, Faast R, Lopata A, Berka J, Norman RJ. The LH/CG bioactivity in the common marmoset (Callithrix jacchus) is due to a chorionic gonadotropin molecule with a structure intermediate between hCG and hLH. Biol. Reprod. 1995;53:380-389. Tozawa H, Brannstrom M, Petrucco O, Walker S, Chambers H, Pascoe V, Norman RJ. Distribution of leukocytes subtypes in the sheep ovary after laser drilling. Hum Reprod 1995 10:544-550. Wang L-J, Brannstrom M, Pascoe V, Norman RJ. Cellular composition of primary cultures of human granulosa-lutein cells and effects of cytokines. Reprod Fertil and Develop 1995;7:21-26. 1994 Bacich DJ, Rohan RM, Norman RJ, Rodgers RJ. Characterization and relative abundance of alternatively spliced luteinizing hormone receptor messenger ribonucleic acid in the ovine ovary. Endocrinology 1994;135;735-744.

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Brannstrom M, Pascoe V, Norman RJ, McClure. Localization of leukocyte subsets in the follicle wall and in the corpus luteum throughout the human menstrual cycle. Fertil Steril, 1994;61:488493. Brannstrom M, Norman RJ, Seamark RF, Robertson SA. The rat ovary produces cytokines during ovulation. Biol Reprod 1994;50:88-94. McLoughlin JW, Goodchild KS, Norman RJ. Finger-prick - an alternative to venipuncture for the assessment of endocrine profiles in women. Fertil Steril 1994;62:886-888. Norman RJ, Brannstrom M. White cells and the ovary - incidental invaders or essential effectors? J Endocrinology 1994;140:333-336. Norman RJ, Brannstrom M. effectors. J Endocrinol 1994 White cells and the ovary - incidental invaders or essential

Wang XJ, Warnes GM, Norman RJ, Kirby CA, Clark AM, Matthews CD. Embryo viability and implantation. Human Reprod 1994;2:184-186. 1993 Brannstrom M, Norman RJ. Involvement of leukocytes and cytokines in the ovulatory process and corpus luteum function. Hum Reprod 1993;8(1):1762-1775. Brännström M, Wang L, Norman RJ. Effects of cytokines on prostaglandin production and steroidogenesis of incubated preovulatory follicles of the rat. Biol Reprod 1993;48:165-171. Brännström M, Wang L, Norman RJ. Ovulatory effects of interleukin 1ß on the perfused rat ovary. Endocrinology 1993;132:399-404. Norman RJ, de Medeiros S, Amato F, Davis G, Davy M. Beta core fragment of human chorionic gonadotropin in cervical intraepithelial neoplasia (CIN). Gynaecol Oncol 1993;49:1618. Rayner TE, Chen BN, McLoughlin JW, Menadue MF, Norman RJ, Oliver JR. Prostaglandin F2 mediates platelet-activating factor-stimulated atrial natriuretic factor release from the isolated rat heart. Endocrinology 1993;133(3):1108-1115. 1992 de Medeiros SF, Amato F, Bacich D, Wang L, Matthews CD, Norman RJ. Distribution of the beta core hCG fragment in body fluids. J. Endocrinol 1992;135:161-174. de Medeiros SF, Amato F, Matthews C, Norman RJ. Comparison of specific immunoassays for detection of ß-core fragment of hCG in body fluids. J. Endocrinol. 1992;135:175-188. Haan EH, Serjeantson SW, Norman RJ, Rollond AK, Antonis P, Richards RI, Penfold JL. Prenatal diagnosis and successful intrauterine treatment of a female fetus with 21-hydroxylase deficiency. Medical Journal of Australia, 1992;156:132-135. Ledger W, Clark A, Olesnicky G, Norman R. Life-threatening rupture of an interstitial ectopic pregnancy arising from oocyte donation: failure of early detection by quantitative human chorionic gonadotropin (hCG) and progesterone estimation. Journal of Assisted Reproduction and Genetics 1992;9:289-291. Norman RJ, Gilmore TA, McLoughlin JW. Simple quantitative measurement of serum choriogonadotropin compared with immunoradiometric, immunoenzymetric and cheniluminescent assays. Clinical Chemistry Clin. Chem. 1992;38:144-147.

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Norman RJ, McLoughlin JW, Borthwick GM, Yohkaichiya T, Matthews CD, MacLennan AH, de Kretser DM. Inhibin and relaxin concentrations in early singleton, multiple and failing pregnancy: relationship to gonadotropin and steroid profiles. Fert Steril 1992;59:130-137. Wang L, Brännström M, Robertson SA, Norman RJ. Tumor necrosis factor in the human ovary: presence in follicular fluid and effects on cell proliferation and prostaglandin production. Fert Steril 1992;58:934-940. Wang L, Norman RJ. Concentrations of immunoreactive interleukin 1 and interleukin 2 in human preovulatory follicular fluid. Hum Reprod. 1992; 7:147-150. Wang L, Pascoe V, Petrucco OM, Norman RJ. Distribution of leukocyte subpopulations in the human corpus luteum. Hum. Reprod. 1992; 7:197-202. 1991 Cain HJ, Pannall PR, Kotasek D, Norman RJ. Choriogonadotropin-mediated thyrotoxicosis in a man. Clin. Chem. 1991;37: 1127-1131 De Medeiros S, Amato F, Norman RJ. The stability of beta core fragment of hCG. Obstetrics & Gynaecology 1991;77: 53-59. Irving RA, Noakes TD, Buck R, van-Zyl-Smit R, Raine E, Godlonton J, Norman RJ. Evaluation of renal function and fluid homeostasis during recovery from exercise-induced hyponatremia. J Appl Physiol 1991;70(1):342-8 Matthews CD, Warnes GM, Norman RJ, Phillipson G, Kirby CA, Wang X. The leuprolide flare regime for in vitro fertilization/gamete intrafallopian transfer and embryo cryopreservation. Hum. Reprod. 1991;6:817-822. Norman RJ, Warnes GM, Segal S, McLoughlin J, Matthews CD. Decrease in luteal gonadotrophin concentrations in conception cycles following in vitro fertilization/gamete intrafallopian transfer. Fertility & Sterility 1991;55: 125-130. Norman RJ, Warnes GM, Wang X, Cranwell L, Kirby CA, Matthews CD. Differential effects of gonadotrophin releasing hormone agonists administered as desensitising or flare protocols on hormonal function in the luteal phase of hyperstimulated cycles supported with human chorionic gonadotrophin. Human Reproduction 1991;6:206-213 Norman RJ. Investigation and management of hirsutism. RACOG Resource Unit 72 1991 Norman RJ, de Medeiros S. Treatment of female infertility. Current Therapeutics 1991;32: 4146 Norman RJ. When a positive pregnancy test isn't. 1991;154:718-719 Medical Journal of Australia

Wang L, Robertson S, Seamark RF, Norman RJ. Lymphokines, including interleukin-2 alter gonadotrophin-stimulated progesterone production and proliferation of human granulosa lutein cells in vitro. J. Clin. Endocrinol. Metab. 1991;72: 824-31. 1990 Hague WM, Norman RJ. Recent advances in understanding of normal hormone mechanisms of the female reproductive system. Current Opinion in Obstetrics and Gynecology 1990;2: 363369. Mahabeer S, Naidoo C, Norman RJ, Jialal I, Govender T, Haneef R, Dunn R, Joubert SM. 125I -insulin binding to circulating erythrocytes, monocytes and cultured fibroblasts in non-obese patients with polycystic ovarian disease. Diabetes Research 1990;13(3):139-44.

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Mahabeer S, Naidoo C, Norman RJ, Jialal I, Reddi K, Joubert SM. Metabolic profiles and lipoprotein lipid concentrations in non-obese and obese patients with polycystic ovarian disease. Hormone and Metabolic Research 1990;22: 537-540. Mahabeer S, Norman RJ. Insulin levels and 125I-insulin binding to monocytes in a non obese pregnant woman with polycystic ovarian disease. Diabetes Research 1990;14:197-200. Noakes T, Norman RJ, Buck RH, Godlonton J. Stevenson K, Pittaway D. The incidence of hyponatraemia during prolonged ultraendurance exercise. Med Sci Sports Exerc 1990;22: 165170. Noakes TD, Norman RJ, Buck RH, Godlonton J, Stevenson K, Pittaway D. The incidence of hyponatremia during prolonged ultraendurance exercise. Med Sci Sports Exerc 1990; 22(2):165-70. Norman RJ. Aetiology & management of early pregnancy loss. Healthright 1990;9:22-24 Norman RJ, Buck RH, Akar B, Mayet N, Moodley J. Detection of a small molecular weight species of human chorionic gonadotropin (hCG beta core) in the urine of patients with carcinoma of the cervix and cervical intraepithelial neoplasia: comparison with other assays for chorionic gonadotropin and its fragments. Gynec Oncol 1990;37: 254-259. Norman RJ, Buck RH, de Medeiros S. Measurement of hCG. Indications and techniques for the clinical laboratory. Annal Clin Biochem 1990;27: 183-194. Norman RJ, Reddi K. Prostaglandins in dysfunctional labour - evidence for altered production of prostaglandin F2 alpha. Reproduction, Fertility and Development 1990;2: 563-574. Norman RJ, van der Spuy Z. Reproductive Endocrinology in Africa. Progress in Obstetrics & Gynaecology 1990;8: 335-350. Reddi K, Deppe WM, Norman RJ, Increased intermittent prostaglandin release from amnion detected by a new superfusion technique for full thickness fetal membrane. Prostaglandins 1990;39: 601-610. Spencer RF, Bullock R, Cooper K, Norman RJ, Becker PJ. The effect of a brain lesion on bone healing. J. Orthopaedic Res. 1990;8: 646-650. Wang L, Warnes GM, Kirby CA, Matthews CD, Norman RJ. Luteal function associated with single, multiple and ectopic implantation in natural cycles or after ovarian hyperstimulation

for in vitro fertilization/gamete intra-fallopian transfer. Hum Reprod 1990;5: 476-480.

1989 Mahabeer S, Jialal I, Norman RJ, Naidoo C, Reddi K, Joubert SM. Insulin and C-peptide secretion in non obese patients with polycystic ovarian syndrome. Horm Metab Research 1989;21: 502-506 Moodley J, Norman RJ. Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. Prostaglandins, Leukotrienes & Medicine 1989; 37: 145-147. Norman RJ. Analytical and clinical sensitivity and specificity in pregnancy testing. Amer J Obstet Gynecol 1989;161: 835 Padayachi T, Moodley J, Norman RJ, Heyns A. Termination of pregnancy with mifepristone after intrauterine demise: clinical and hormonal effects. South African Medical Journal 1989;75: 540-542

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Padayachi T, Pegoraro RJ, Holloway G, Joubert SM, Norman RJ. Changes in the binding characteristics of oestrogen and progesterone in uterine and intrauterine tissue with the progression of human pregnancy. J Steroid Biochem 1989;33: 535-540. 1988 Brock-Utne JG, Gaffin SL, Wells MT, Gathiram P, Sohar E, James MF, Morrell DF, Norman RJ. Endotoxaemia in exhausted runners after a long-distance race. S Afr Med J 1988; 73:533-536 Buck RH, Joubert SM, Norman RJ. Serum progesterone in the diagnosis of ectopic pregnancy: a valuable diagnostic test? Fertil Steril 1988; 50: 752-755 Desai RK, Deppe WM, Norman RJ, Govender T, Joubert SM. The Simultrac FT4/TSH assay evaluated as a first-line thyroid function test. Clin Chem 1988; 34:1488-1491. Desai RK, Norman RJ, Jialal I, Joubert SM. Spectrum of thyroid function abnormalities in gestational trophoblastic disease. Clin Endocrinol (Oxf) 1988; 29: 145-147 Norman RJ, Buck RH, Joubert SM. Comparison of human chorionic gonadotrophin concentrations in the sera of patients with normal and abnormal pregnancy measured by radioimmunoassay and immunoradiometric assay. S Afr Med J 1988; 75: 318-319 Norman RJ, Buck RH, Kemp M, Joubert SM. Impaired corpus luteum function in ectopic pregnancy cannot be explained by altered hCG bioactivity. J Clin Endocrinol Metab 1988; 66:1166-1169. Norman RJ, Buck RH, Rom L, Joubert SM. Blood or urine measurement of human chorionic gonadotropin for detection of ectopic pregnancy? A comparative study of quantitative and qualitative methods in both fluids. Obstet Gynecol 1988; 71:315-318 Norman RJ, Buck RH. Choriogonadotropin in urine or serum for detection of ectopic pregnancy? Clin Chem 1988; 34:641 Norman RJ, Coutts PB, Godlonton J. Organization of a field laboratory at an ultra-marathon. Clin Chem 1988; 34:641 Norman RJ, Miller J, Millar RP, Joubert SM. Treatment of menstrually-induced acute intermittent porphyria by a long-acting gonadotrophin-releasing hormone agonist (D Tryp Pro N ethylamine) LHRH. Case Report. Br J Obstet Gynaecol 1988; 95:192-194 Padayachi T, Norman RJ, Dhavaraj T, Kemp M, Joubert SM. Serial oxytocin levels in amniotic fluid and maternal plasma during normal and induced labour. Br J Obstet Gynaecol 1988; 95: 888-893 Padayachi T, Norman RJ, H. Moodley J, Heyns A. Mifepristone and induction of labour in second half of pregnancy. Lancet 1988; i:647 (letter) Reddi K, Kambaran SR, Philpott RH, Norman RJ. Intrauterine pressure studies in multigravid patients in spontaneous labour: effect of oxytocin augmentation in delayed first stage. Br J Obstet Gynaecol 1988; 95:771-775. Wittenberg D, Padayachi T, Norman RJ. Hypogonadotropic variant of Klinefelter's syndrome. S Afr Med J 1988; 74: 181-183 1987 Buck RH, Gihwala N, Rom L, Joubert SM, Norman RJ. Detection of urinary human chorionic gonadotropin by rapid immunoconcentration method is the first-line test for suspected ectopic pregnancy. Fertil Steril 1987; 48:761-765

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Buck RH, Pather N, Moodley J, Joubert SM, Norman RJ. Bedside application of an ultrasensitive urine test for hCG in patients with suspected ectopic pregnancy. Ann Clin Biochem 1987; 24:268-272 Moodley J, Rampersadh S, Becker P, Norman RJ, O'Donnell D. eclampsia. S Afr Med J 1987; 72:382-385 Serum calcium levels in

Norman RJ, Haneef R, Buck RH, Joubert SM. Measurement of the free alpha subunit of human glycoprotein hormones by a monoclonal antibody-based immunoradiometric assay and further exploration of antigenic sites on the choriogonadotropin molecule. Clin Chem 1987; 33:11471157 Norman RJ, Menabawey M, Lowings C, Buck RH, Chard T. Relationship between blood and urine concentrations of intact human chorionic gonadotropin and its free subunits in early pregnancy. Obstet Gynecol 1987;69:590-593 Norman RJ, Mobbs C, Joubert SM. Effects of severe postpartum haemorrhage on puerperal pituitary function. J. Obstet Gynecol 1987; 7:197-200 Padayachi T, Pegoraro RJ, Hofmeyr J, Joubert SM, Norman RJ. Decreased concentrations and affinities of oestrogen and progesterone receptors of intrauterine tissue in human pregnancy. J Steroid Biochem 1987; 26: 473-479 Poulsen HK, Westergaard JG, Teisner B, Bolton AE, Norman RJ, Grudzinskas JG. Measurements of hCG and PAPP-A in uncommon types of ectopic gestation. Eur J Gynecol Reprod Biol 1987; 26:33-37 Reddi K, Norman RJ, Deppe WM, Kemp M, Machattie T, Joubert SM. Amniotic membrane production of prostaglandin F2a is reduced in dysfunctional human labor - results of in vivo and in vitro studies. J Clin Endocrinol Metab 1987; 65:1000-1005 Reddi K, Norman RJ, Joubert SM. Differential regulation of prostaglandin production by inhibitors and stimulators in amniotic fluids during normal and dysfunctional labour. Prostaglandins 1987; 34:477-492 1986 Botha JH, Robinson KM, Ramchurren N, Reddi K, Norman RJ. Human esophageal carcinoma lines : prostaglandin production, biological properties and behaviour in nude mice. J Natl Canc Inst 1986; 76:1053-1056 Buck RH, Joubert SM, Norman RJ. A beside urine test for human chorionic gonadotropin as sensitive as serum radioimmunoassay. Clin Chem 1986; 32:1596 Buck RH, Norman RJ, Reddi K, Moodley J, Joubert SM. Evaluation of various methods for urinary choriogonadotropin in the early diagnosis of ectopic pregnancy. Clin Chem 1986; 32:879-883. Moodley J, Kistnasamy MB, Reddi K, Norman RJ, Reinach SG. Amniotic fluid prostacyclin in African women with eclampsia. Clin Exp Hypertension 1986; B5:29-38 Norman RJ, Buck RH, Reddi K. Urine human chorionic gonadotropin in ectopic pregnancy. Fertil Steril 1986; 45:306 Norman RJ, Menabawey M, Gard T, Lowings C, Chard T. Free subunits of human chorionic gonadotropin do not respond to TRH. J Obstet Gynecol 1986; 7:141-142 Norman RJ, Naidoo C, Reddi K, Khatree M, Joubert SM. Clinical studies in African women with isolated gonadotropin-releasing hormone deficiency. S Afr Med J 1986; 69:546-548

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Norman RJ, Naidoo C, Reddi K, Vink G, Joubert SM. Endocrine studies in African women with isolated gonadotropin-releasing hormone deficiency. S Afr Med J 1986; 70:152-155 Norman RJ, Reddi K, Kemp M, Joubert SM, Patel F. Sensitive urine tests and human chorionic gonadotropin secreted during ectopic pregnancy. Br Med J 1986; 292:590-591 Padayachi T, Norman RJ, Reddi K, Shweni PM, Philpott RH, Joubert SM. Changes in amniotic fluid prostaglandins with oxytocin-induced labor. Obstet Gynecol 1986;69:610-615 Rampersadh SP, Moodley J, Norman RJ. Serum ionized calcium concentrations in eclampsia. S A Med J 1986;72: 382-385. 1985 Meineke K, Patel R, Norman RJ, Sadhabiriss, A. Phosphatidyl glycerol in amniotic fluid : the use of a simple one-dimensional technique. S Afr J Med Lab Tech 1985; 31:22-25 Naidoo C, Norman RJ, Khatree M, Joubert SM. Idiopathic premature ovarian failure : a clinical and biochemical study amongst Black South Africans. S Afr Med J 1985; 68:91-94 Norman RJ, Chard T. The assessment of placental function. Physiological Development of the Fetus and Neonate. Jones CT & Nathanielsz P, eds. Academic Press 1985; pp691-694 Norman RJ, Joubert SM. Immunoreactive oestrogens and progesterone in amniotic fluid in twin pregnancies. Br J Obstet Gynaecol 1985; 92:216-219 Norman RJ, Lowings C, Chart T. Dipstick method for human chorionic gonadotropin suitable for emergency use on whole blood and the other fluids. Lancet 1985; I:19-20 Norman RJ, Lowings C, Oliver T, Chard T. Doubts about hCG as a thyroid stimulator. Lancet 1985; I:1096-1097 Norman RJ, Lowings C, Oliver T, Chard T. Human chorionic gonadotropin and subunits heterogeneity in serum of male patients with tumours of the genital tract. Clin Endocrinol 1985; 23:25-34 Norman RJ, Marivate M, Joubert SM. Human twin pregnancy in the study of endocrine factors responsible for parturition. Physiological Development of the Fetus and Neonate. Jones CT & Nathanielsz P, eds. Academic Press 1985; pp483-487 Norman RJ, Poulton T, Gard T, Chard T. Monoclonal antibodies to human chorionic gonadotropin: implications for antigenic mapping, immunoradiometric assays and clinical applications. J. Clin Endocrinol Metab 1985; 61:1031-1038 Norman RJ, Reddi K, Padayachi T, Joubert SM. Signals for human birth. S Afr J Sci 1985; 81: 438-439 Norman RJ, Reddi K, Richards A, Hammond MG, Joubert SM. Male transmission of the gene for isolated gonadotropin-releasing hormone deficiency. Fertil Steril 1985; 43:225-228 Reddi K, Kambaran A, Joubert SM, Philpott RH, Norman RJ. Decreased concentrations of prostaglandin F2-alpha in delayed labour - a model for studies on the control of prostaglandin production by the uterus. Prostaglandins, Leukotrienes, Lipoxins. Plenum Publishing Corporation 1985; pp457-464. Reddi K, Norman RJ. Prostaglandin inhibitory compounds in the initiation of human labour. Lancet 1985; I:1508 1984

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Jialal I, Naidoo C, Norman RJ, Rajput MC, Omar MAK, Joubert SM. Sheehan's syndrome. Obstet Gynaecol 1984; 63:15-20

Pituitary function in

Krieger MS, Norman RJ, Moodley J, Jialal I. A reversible tubular lesion in pregnancy-induced hypertension detected by urinary beta 2-microglobulin. Obstet Gynaecol 1984; 63:533-536 McMullan RJ, Norman RJ, Marivate M. Pregnancy-induced hypertension in twin pregnancy. Br J Obstet Gynaecol 1984; 91:240-243 Moodley J, Norman RJ, Reddi K. Central venous concentrations of immunoreactive prostaglandins 6-keto F1-alpha, E and F in eclampsia. Br Med J 1984; 288:1487-1489 Moodley J, Norman RJ. Amniotic fluid prostanoids in pre-eclampsia. Obstet Gynaecol 1984 65:69-71 Norman RJ, Deppe WM, Joubert SM, Marivate M. Umbilical arterial concentrations of androstenedione increase in early labour in the leading twin fetus. Br J Obstet Gynaecol 1984; 91:776-780 Norman RJ, Desai RK, Deppe WM, Joubert SM. The value of serum free T3 and free T4 in the detection of hypothyroidism. Clin Chem 1984; 30:169-170 Norman RJ, Maharaj C, Adhikari M, Joubert SM. Adrenal sensitivity to ACTH in twin neonates effect of birth order and growth retardation. S Afr Med J 1984: 66:90-92 Patel R, Norman RJ, Moodley J, Sadhabris A. Phosphatidyl glycerol in amniotic fluid: the use of a simple unidimensional technique in clinical practise. S Afr Med J 1984; 65:348-351 Reddi K, Kambaran S, Norman RJ, Joubert SM, Philpott RH. Abnormal concentrations of prostaglandins in amniotic fluid during delayed labour in multigravid patients. Br J Obstet Gynaecol 1984; 91:781-787 1983 Norman RJ, Deppe WM, Coutts PC, Marivate M, Joubert SM. Twin pregnancy as a model for studies in fetal cortisol concentrations in labour: relation to prostaglandins, prolactin and ACTH. Br J Obstet Gynaecol 1983; 90:1033-1039 Norman RJ, Deppe WM, Joubert SM. Prolactin cortisol and thyroxine levels and the premature infant. S Afr Med J 1983; 64:228-229 Norman RJ, Joubert SM, Marivate M. Amniotic fluid phospholipids and glucocorticoids in multiple pregnancy. Br J Obstet Gynaecol 1983; 90:51-55 Norman RJ, Joubert SM. Fetal adrenal gland maturation in growth-retarded twin pregnancies. Acta Geneticae Medicae et Gemellol 1983; 31:259-262 Norman RJ, Joubert SM. The lecithin/sphingomyelin ratio in twin pregnancies. Acta Geneticae Medicae et Gemellol 1983; 31:255-258 Norman RJ, Marivate M. Neurological maturity at birth in the growth-retarded twin fetus. S Afr Med J 1983; 63:3 Norman RJ. The twin pregnancy as a model for studies in the endocrinology of parturition and development. MD Thesis 1983, University of Natal 1982 Marivate M, Norman RJ. Obstetric problems in the developing world. Twins. Clin Obstet Gynaecol 1982; 9:723-745

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Norman RJ, Joubert SM, Botha JH. Measurement of prostaglandins in biological fluids. S Afr Med J 1982; 61:4 Norman RJ, Joubert SM. Routine measurement of phosphatidylglycerol in amniotic fluid. S Afr Med 1982; 61:839-841 Norman RJ, Martin R, Marivate M. Maternal prostaglandin levels after vaginal examination in twins. S Afr Med J 1982; 61:833-834 Pather R, Moodley J, Norman RJ. Assay of human chorionic gonadotrophin in the patient with suspected ectopic pregnancy. S Afr Med J 1982; 61:835-387 Skelly H, Marivate M, Norman RJ, Kenoyer G. Consumptive coagulopathy in triplet pregnancy. Am J Obstet Gynaecol 1982; 142:595-596 1981 Jialal I, Joubert SM, Norman RJ, Pitsoe P. Hypomagnesaemia-hypocalcaemia syndrome presenting in the post-partum period. S Afr Med J 1981; 60:793-794 Norman RJ, Bredenkamp BLF, Joubert SM, Beetar C. pregnancies. Prostaglandins & Medicine 1981; 6:309-316. Fetal prostaglandin levels in twin

Norman RJ, Green-Thompson RW, Jialal I, Soutter WP, Pillay NL, Joubert SM. Hyperthyroidism in trophoblastic neoplasia. Clin Endocrinol 1981; 15:395-401 Norman RJ, Joubert SM. Medicine 1981; 8:171-172. Fetal urinary prostaglandins. Prostaglandins, Leukotrienes &

Soutter WP, Norman RJ, Green-Thompson RW. The management of choriocarcinoma causing severe thyrotoxicosis. Br J Obstet Gynaecol 1981; 88:938-943. 1980 Jialal I, Norman RJ, Asmal AC. Gonadotrophin-sparing hypopituitarism. S Afr Med J 1980; 58:656-657 Norman RJ, Brown I McL. Unilateral tubo-ovarian involvement in pelvic inflammatory disease. Central Africa J Med 1980; 26:213-217 Norman RJ, Marivate M, Skelly H. Growth retardation in twins. S Afr Med J 1980; 58:991. Norman RJ, Reddi K, Padayachi T, Joubert SM. Mechanisms that trigger birth - the beginning of the end or the end of the beginning? Research in South Africa. MRC Publications, Cape Town 1988 1987 Jialal I, Norman RJ. Editorial: South African Journal of Continuing Medical Education 1987; 5: 23 Norman RJ, van der Spuy Z. Investigation and management of hirsutism. S Afr J Continuing Med Education 1987; 5: 37-44 1986 Norman RJ. The detection of early pregnancy. Editorial. S Afr Med J 1986; 69:531-532 1978 Norman RJ. Six years experience of symphysiotomy in a teaching hospital. S Afr Med J 1978; 54:1121-1125 1973

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Norman RJ. Alcohol: its use and abuse among two cultures in Rhodesia. I Central Africa Journal of Medicine 1973; 20:39-43 Norman RJ. Alcohol: its use and abuse among two cultures in Rhodesia. II Central Africa Journal of Medicine 1973; 20:62-64 Norman RJ. Alcohol: its use and abuse among two cultures in Rhodesia. III Journal of Medicine 1973; 20:86-90 Central Africa

1972 Norman RJ. Light and the pars intermedia of the ferret. BSc (Hons) Thesis 1972, University of Birmingham

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Conference Presentations and Abstracts

2009 Hart R, Hickey M, Doherty D, Norman R, Atkinson H, Sloboda D. SGI Conference, Glasgow March 2009. "Circulating Anti-Mullerian Hormone (AMH) levels are significantly associated with the presence of PCOS in adolescent girls". Hart R, Doyerty D, Sloboda D, Newnham J, Atkinson H, Norman R, Hicky M. SGI Conference, Glasgow March 2009. "The influence of antenatal growth patterns and maternal smoking upon markers of ovarian reserve in adolescence" Sloboda D, Hickey M, Doherty D, Atkinson H, Norman R, Hart R. SGI Conference, Glasgow March 2009. "Maternal androgen levels at 18 and 36 weeks gestation, and cord androgen levels do not predict polycystic ovarian syndrome in adolescence" Norman R. First International Asia Pacific Meeting on Polycystic Ovary Syndrome, Hong Kong. 17-18 Janaury 2009. "Measuring androgens ­ do they mean anything?"

2008 R J Norman, Fertility Society of Australia 27th Annual Scientific Meeting, 19-22 October 2008, Brisbane, Australia. "Evidence for Metformin in Ovulation Induction" R J Norman, Fertility Society of Australia 27th Annual Scientific Meeting, 19-22 October 2008, Brisbane, Australia. "Preparing for Pregnancy ­ Preconceptional Rights and Responsibilities" Norman RJ. Taiwanese Society for Reproductive Medicine Annual Meeting, August 30, 31 2008 in Taipei. "Infertility, IVF and lifestyle ­ facing the next frontier for treatment" K R Dunning, L K Akison, D L Russell, R J Norman, R L Robker. Thirty ninth Annual Conference of the Society for Reproductive Biology, Melbourne, Australia, 25-28 August 2008. "Normal follicle Growth and Maturation in a Three-Dimensional in vitro Culture System: Follicular Environment Manipulation and Assessment of Oocyte Outcomes." R L Thomson, J D Buckley, M Noakes, P Clifton, RJ Norman, G D Brinkworth. 2008 Annual Scientific Meeting of The Obesity Society October 3-7, 2008. "Effects of a hypocaloric diet with and without exercise training on body composition, metabolic risk profile and reproductive function in overweight and obese women with polycystic ovary syndrome. Norman RJ. Royal Australasian College of Physicians Congress, Adelaide, SA 11-15 May 2008. "How do we define and treat PCOS ­ International Consensus Statements". Norman RJ. Serono Symposia InternationaL Pre-ASPIRE conference, Singapore 10-13 April 2008. "Clinical Management of PCOS", "Consensus View of Polycystic Ovary Syndrome". Norman RJ. 9th Post Graduate Refresher Course, Singapore General Hospital. 26-29 March 2008. "PCOS ­ Current Concepts", "AMH ­ the Ovarian Reserve Hormone", "Feast and Famine in Reproduction". C Sturgeon, P Berger, J-M Bidart, S Birken, C Burns, R Norman, U-H Stenman LabMed2008, the XXXI Nordic Congress in Clinical Chemistry. "Standardization of hCG: Progress report from the IFCC Working Group"

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Norman RJ. Updates in Infertility Treatment 2008, January 30 ­ February 1, 2008, Cape Town, South Africa. "The next frontier in human reproduction ­ lifestyle and reproductive health". 2007 Norman RJ. Joint RCOG/ESHRE conference 15,16 November 2007 at RCOG, London. "Polycystic Ovary Syndrome ­ A condition of our time" Norman RJ. 5th International Congress on Developmental Origins of Health and Disease, 6-10 November 2007, Perth, Western Australia. "Genetic/Epigenetic and environmental origins of PCOS" De Lacey S, Davies M, Homan G, Briggs N, Norman R. Fertility Society of Australia, Annual Scientific Meeting 9-12 September 2007, Hobart Tasmania. Poster presentation ­ Factors and Perceptions that influence women's decisions to have a single embryo transferred. Norman RJ. 11th Australian Menopause Society Congress, 14-16 September 2007, Adelaide, Australia. Polycystic Ovary syndrome Beyond Fertility. Norman RJ. Fertility Society of Australia 2007 Conference, Hobart, Tasmania 9-12 September 2007. Empty Cots and Silent Spring in an Age of Plenty ­ What Our Lifestyle is Doing top our Reproductive Health. Norman RJ. IFFS 2007 April 29 ­ May 03 2007, Durban, South Africa. Obesity, Famine and Reproductive Health. Hickey TE, Tilley WD, Norman RJ. ENDO 2007, 2-5 June Toronto, Canada. Functional Androgen Receptor Signalling is Evident in and Modulates Steroidogenic Output of a Human Granulosa Tumour Cell Line, KGN Norman RJ. 6th Singapore Congress in Obstetrics and Gynaecology 21-25 March 2007, Singapore. "Is ICSI safe ­ Perinatal Outcome of ICSi Babies" 2006 Norman RJ. RANZCOG 2006 Annual Scientific Meeting 15-18 October, 2006. Perth, Australia. Reproductive Problems Associated with Obesity. Norman RJ. RANZCOG 2006 Annual Scientific Meeting 15-18 October 2006. Perth, Australia. Fertility after 40. Norman RJ. 10th International Congress on Obesity, 3-8 September 2006, Sydney, Australia. Obesity and the PCOS Hickey TE, Norman RJ. International Conference on Polycystic Ovary Syndrome, Harbin, China. August 2006. Androgen receptor dynamics in relation to the genetics and pathology of polycystic ovary syndrome. Robker, R, Minge C, Bennett B, Lane M, Norman RJ. Society for the Study of Reproduction 38th Annual Meeting, Omaha, NE, USA. 29 July ­ 1 August 2006. Peri-ovulatory rosiglitazone treatment reverses impaired embryo development associated with obesity. Poster presentation. 2005

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Moran LJ, Noakes M, Clifton PM, Wittert GA, Williams G, Norman RJ. Effective weight loss and maintenance strategies in polycystic ovary syndrome. Nutrition Society of Australia Annual National Conference, Melbourne. 30 November ­ 3 December 2005. Davies M, Wang J, Norman R. Elective Single Embryo Transfer Reduces Spontaneous Abortion. Fertility Society of Australia Annual Scientific Meeting 4-7 September 2005. Christchurch New Zealand. Wang J, Davies M, Norman R. Improvement in IVF Techniques Reduces Pregnancy Wastage. Fertility Society of Australia Annual Scientific Meeting 4-7 September 2005. Christchurch New Zealand. Stankiewicz M, Warnes G, Gilmore A, Norman R. Unanticipated Failure of oocyte Recovery: A Diagnostic and Recovery Algorithm. Fertility Society of Australia Annual Scientific Meeting 4-7 September 2005. Christchurch New Zealand. Conyers K, Barry M, Henshaw R, Norman R, Lane M. Adoption of a Policy of Single Embryo Transfer for Good Prognosis Patients Does Not Affect Pregnancy Rates but Eliminates Twins. Fertility Society of Australia Annual Scientific Meeting 4-7 September 2005. Christchurch New Zealand. Hart R, Sloboda DM, Norman R, Doherty D, Hickey M. The Polycystic Ovary Syndrome (PCOS) n Adolescence an Intrauterine Exposure to Maternal Androgens. 3rd International Congress on Developmental Origins of Health & Disease. Toronto, Canada Nov 16-19 2005 Elliott J, Norman RJ, Maclennan A, Olsson A. A model for holistic care of women at menopause in a dedicated centre staffed by a team of general medical practitioners, specialists and nurses. Abstract and poster presentation, 11th World Congress on the Menopause, 18-22 October, Buenos Aires, Argentina. Davis S, Papalia M, Norman RJ, O'Neill S, Redelman M, Williamson M, Stuckey B, Gard'ner K, Humberstone A. Efficacy and Safety of a Testosterone (T) Metered-Dose Transdermal Spray in Premenopausal Women: a Placebo-Controlled, Randomised, Parallel Dose-Ranging Study. Oral presentation at the 16th Annual Meeting of The North American Menopause Society , September 28 ­ October 1, 2005. San Diego, CA, USA Minge CE, Bennett VV, Tsagareli V, Norman RJ, Lane M, Robker RL. Effects of diet-induced obesity on ovarian function and female fertility. Proceedings of North Western Adelaide Health Service Research Day Adelaide 21st October 2005. Hickey TE, Alvino HJ, Gilchrist RB, Norman RJ. Genotype and epigenotype in polycystic ovary syndrome: evidence for a casual gene on the X chromosome. Proceedings of North Western Adelaide Health Service Research Day Adelaide 21st October 2005. Davies MJ, Wang JX, Norman RJ. Elective single embryo transfer reduces spontaneous abortion. Fertility Society of Australia, Christchurch New Zealand 4-7 September 2005. Hickey TE, Milner CR, Sheetz B, Legro RS, Norman RJ. Differential patterns of X-inactivation among sisters in family groups with polycystic ovary syndrome (PCOS). 48th Annual Meeting, Endocrine Society of Australia. Perth WA 4-7 September 2005. Hickey TE, Marrocco DL, Amato F, Ritter LJ, Norman RJ, Gilchrist RB, Armstrong DT. Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells. SRB 36th Annual Conference, Perth WA 4-7 September 2005.

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Minge CE, Bennett BB, Tsagareli V, Norman RJ, Lane M, Robker RL. Effects of diet-induced obesity on ovarian function and female fertility. SRB 36th Annual Conference, Perth WA 4-7 September 2005. S Davis, M Papalia, R Norman, S O'Neill, M Redelman, M Wiliamson, B Stuckey, K Gard'ner, A Humberstone. Effect of Transdermal Testosterone (T) on Sexual Function in Premenopausal Women with Low Libido: a Placebo-Controlled, Randomised, Parallel, Dose-Ranging Study. 9th Australasian Menopause Society Congress, 22-24 September 2005, Gold Coast, Queensland, Australia. Oral presentation. M Stankiewicz, G Warnes, A Gilmore, R Norman. Unanticipated failure of oocyte recovery: a diagnostic and recovery algorithm. Fertility Society of Australia Annual Scientific Meeting 4-7 September 2005, Christchurch New Zealand. Oral presentation. Van der Hoek KH, Minge CE, Norman RJ, Robker RL. Regulated expression of the C-FMS receptor characterises distinct ovarian macrophage populations. SRB 36th Annual Conference, Perth WA 4-7 September 2005. Wang JX, Davies MJ, Norman RJ. Improvement in IVF techniques reduces pregnancy wastage. Fertility Society of Australia, Christchurch New Zealand 4-7 September 2005. P Dabadghao, B Roberts, M Davies, J Wang, R Norman. Increased risk of developing abnormal glucose tolerance in women with polycystic ovary syndrome on follow up. 21st Annual meeting of ESHRE, Copenhagen, 19-22 June 2005. Davies MJ, Moore VM, Norman RJ. Growth in early life and subsequent symptoms of polycystic ovary syndrome on young women. European Society for Human Reproduction and Endocrinology, Copenhagen Denmark 19-22 June 2005. Norman RJ, Wang J. Evidence Based Management of Hirsutism for PCOS Women. The Endocrine Society's 87th Annual Meeting, San Diego, USA, 4-7 June 2005. C Haynes, N Ryan, R Norman, R Robker. The CSF-1/ c-fms signalling system regulates ovarian macrophage differentiation and oocyte competence. The Endocrine Society's 87th Annual Meeting, San Diego, USA, 4-7 June 2005. TE Hickey, HJ Alvino, RJ Norman. Granulosa Cells form Polycystic Ovaries have Increased Expression of Androgen Receptor Regulated Kallikrein 3, but Normal Expression of Androgen Receptor and Two Androgen Receptor Co-activators. The Endocrine Society's 87th Annual Meeting, San Diego, USA, 4-7 June 2005. Minge CE, Ryan NK, Norman RJ, Robker RL. The CSF-1/c-fms signalling system regulates ovarian macrophage differentiation and oocyte competence. The Endocrine Society's 87th Annual Meeting, San Diego USA, June 4-7 2005. K Van der Hoek, N Ryan, R Norman. Macrophages Isolated from the Gonadotropin-Stimulated Murine Ovary Produce both Inflammatory and Anti-Inflammatory Mediators. The Endocrine Society's 87th Annual Meeting, San Diego, USA, 4-7 June 2005. Hickey TE, Milner CR, Sheetz B, Legro RS, Norman RJ. Differential patterns of X-inactivation among sisters in family groups with polycystic ovary syndrome (PCOS). Third Annual meeting of the Androgen Excess Society, San Diego USA, 3 June 2005. Oral presentation. Norman RJ. Health related issues in polycystic ovary syndrome. Updates on Polycystic Ovary Syndrome symposium, Hong Kong. March 20, 2005

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Norman RJ. Use of metformin in polycystic ovary syndrome. Updates on Polycystic Ovary Syndrome symposium. Hong Kong. March 20, 2005 Norman RJ. Lessons from Science for Establishing Future Reproductive Health Priorities. Perinatal Society of Australia & New Zealand 9th Annual Congress, Adelaide, SA 13-16 March 2005. 2004 Norman RJ. Diet, exercise and lifestyle modification in women with Polycystic Ovary Syndrome. 2nd Annual World Congress on the Insulin Resistance Syndrome, Los Angeles USA. November 18-20 2004. Kirby C, Warnes L, Norman R. Clinical Procedures as Reporting Elements for Total Quality Management (TQM) in assisted Reproduction. Annual Scientific Meeting of the Fertility Society of Australia. 10-13 October 2004, Adelaide, Australia. Alvino H, Davies M, Norman R, Wang J. Challenges for Recruitment in a Multi Centre Clinical Research Trial. Annual Scientific Meeting of the Fertility Society of Australia, 10-13 October 2004, Adelaide, Australia. Cussons AJ, Stuckey GA, Walsh JP, Burke V, Norman RJ. Polycystic Ovary Syndrome: Are Endocrinologists and Gynaecologists treating the same patients? 47th Annual Scientific Meeting, The Endocrine Society of Australia, Sydney NSW 22-25 August 2004. RJ Norman. "Ovarian leukocytes and cytokines in polycystic ovary syndrome". ESA/SRB Annual Scientific Meeting, Sydney, August 23-25 2004. Hickey TE, Norman RJ. Expression of Prostate Specific Antigen by Ovarian Granulose Cells. To be presented at Endocrine Society of Australia Annual Meeting, Sydney. August 2004. Moran LJ, Noakes M, Clifton PM, Wittert G, Norman RJ. Short term energy restriction (using meal replacements) improves reproductive parameters in polycystic ovary syndrome. Nutrition Society of Australia, Brisbane, 11-13 August 2004. Gilchrist RB, Amato F, Norman RJ. "Superovulation of the marmoset and strategies for developing superovulation for Neo-Tropical primate species. Proceedings of the workshop entitled: NEO-TROPICAL PRIMATE REPRODUCTION held at 15th International congress of Animal Reproduction (ICAR) August 2004, Porto Seguro, Brazil Armstrong DT, Marrocco DL, Hickey TE, Norman RJ, Gilchrist RB. Oocyte-secreted factor(s) augment mitogenic responses of porcine granulose cells to insulin-like growth factor-1 and 5-dihydrostestoserone. US Endocr.Soc. New Orleans USA June 16-19 2004. Cussons AJ, Stuckey GA, Walsh JP, Burke V, Norman RJ. Polycystic Ovary Syndrome; Are Endocrinologists and Gynaecologists treating the same patients? Society for Reproductive Biology 22-25 August 2004, Sydney NSW, Reproduction, Fertility and Development Vol16 (Supplement) 2004. Redman, LM, Hamdorf P, Norman RJ, Westlander G, Scroop GC. "The menstrual cycle or Oral Contraceptive Pill: Can it Benefit or Hinder Exercise I women". 51st Annual Meeting of American College of Sport Medicine Annual Meeting, Indianapolis Convention Centre, Indiana USA. June 2004.

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Redman LM, Scroop GC, Handorf P, Westlander G, Norman RJ. Progestins Influence Energy Metabolism during Exercise in Young, Sedentary Women. Endocrine Society 86th annual Meeting New Orleans USA June 16-19 2004. Norman RJ, "Role of insulin sensitising agents in treatment of PCOS". ENDO 2004, June 16 ­ 19 2004, New Orleans USA Haynes CE, Van Der Hoek K, Norman RJ. Expression and function of peroxisome proliferatoractivated receptors (PPARs) in murine ovarian macrophages. Annual Scientific Meeting of the SA Division of ASMR, Adelaide, 4 June 2004. Haynes CE, Norman RJ, Robker RL. Analysis of ovarian macrophage populations using macrophage-specific green fluorescent protein (GFP) transgenic mice. Society for Reproductive Biology 22-25 August 2004, Sydney NSW, Reproduction, Fertility and Development Vol 16 (Supplement) 2004 Norman RJ, "Polycystic Ovarian Syndrome". International Federation of Fertility Societies 18th World Congress, Montreal, Canada 23-28 May 2004. Hickey TE, Norman RJ. Expression of Prostate Specific Antigen in the Ovary. Australian Society for Medical Research, SA Annual meeting, Adelaide. May 2004. Norman RJ, Polycystic Ovary Syndrome. IFFS 18t World Congress on Fertility and Sterility Montreal, Canada May 23-38 2004. De Lacey, S, Norman R, "Screening out donated embryos that may be genetically affected: should we discard them?" International Federation of Fertility Societies 18th World Congress, Montreal, Canada 23-28 May 2004. Norman RJ (2004) "Weight Control and PCOS". ESHRE/RCOG meeting Thursday and Friday 22 and 23 April 2004, London 2003 de Lacey, S and Norman RJ, (2003) "Should parents of "genetically dubious" embryos be allowed to donate them to another couple?" Annual Scientific Meeting of the Fertility Society of Australia. November 3-5 2003, Perth Helen Alvino, Robert J Norman. Profile of a response to media exposure of female sexuality and research. 7th Australasian Menopause Society Congress in Hobart (13,14 November 2003) Robert J Norman. Cardiovascular Risk in the Reproductive Age. Women with PCOS. American Society for Reproductive Medicine 59th Annual Meeting, San Antonio, Texas (11-15 October 2003) Robert J Norman. Lifestyle Interventions in Women with PCOS. American Society for Reproductive Medicine 59th Annual Meeting, San Antonio, Texas (11-15 October 2003) Robert J Norman. Metformin and the Polycystic Ovary Syndrome. American Society for Reproductive Medicine 59th Annual Meeting, San Antonio, Texas (11-15 October 2003) Robert J Norman. Gonadotropins and IVF in the PCOS Population ­ What to do Differently. American Society for Reproductive Medicine 59th Annual Meeting, San Antonio, Texas (11-15 October 2003)

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Robert J Norman. "The role of obesity in reproduction" and "Only one at a time ­ reducing multiple pregnancies". RANZCOG Annual Scientific Meeting (17-19 September 2003) In Auckland, New Zealand. Rebecca L Robker, C Wayne Smith, Robert J Norman, Darryl L Russell. Macrophage Migration and Luteal Regression in Ovaries of Leukocyte Adhesion Molecule-Deficient (ICAM-1/-) MICE. Society for Reproductive Biology, Thirty-fourth Annual Conference, Melbourne (14-17 September 2003) C Haynes, K H Van Der Hoek, N K Ryan, S A Robertson, R J Norman. Ovarian Macrophage Regulation of Inflammatory Responses at Ovulation in Murine Ovaries. Society for Reproductive Biology, Thirty-fourth Annual Conference, Melbourne (14-17 September 2003) K H Van Der Hoek, N K Ryan, S A Robertson, R J Norman. The Expression of Ovulatory Mediators by Macrophages Isolated from the Gonadotrophin-stimulated Mouse Ovary. Society for Reproductive Biology, Thirty-fourth Annual Conference, Melbourne (14-17 September 2003) L J Moran, M Noakes, P M Clifton, G A Wittert, N Luscombe, C Galletly, L Tomlinson, R J Norman. Ghrelin and Measures of Satiety are Altered in Polycystic Ovary Syndrome but not Affected by Diet Composition. Endocrine Society of Australia 46th Annual Scientific Meeting. Melbourne (14-17 September 2003) R Wu, N K Ryan, M J Jasper, K H Van der Hoek, R J Norman. Cytokine MRNA Expression by CD14+ Cells (Macrophages/Monocytes) in Human Follicular Fluid. Endocrine Society of Australia 46th Annual Scientific Meeting. Melbourne (14-17 September 2003) T E Hickey, R J Norman. Expression of the Androgen Receptor and Enhancement of FSH Signalling by Dihydrotestosterone in a Granulosa Tumour Cell Line. Endocrine Society of Australia 46th Annual Scientific Meeting. Melbourne (14-17 September 2003) September 2003) Rebecca L Robker, C. Wayne Smith, Robert J Norman and Darryl L Russell. Macrophage Migration and Luteal Regression in Ovaries of Leukocyte Adhesion Molecule-deficient (ICAM-1/-) MICE. The Endocrine Society of Australia 46th Annual Scientific Meeting. Melbourne (14-17 September 2003) Jim Wang, Michael Davies, Robert Norman. "PCOS: Current Concepts, Treatment and Ovulation Induction". International PCOS Symposium, Antalya-Kemer, Turkey. (4-7 September 2003) Rebecca L Robker, C Wayne Smith, Robert J Norman, Darryl L Russell. Macrophage Migration and Luteal Regression in Ovaries of Leukocyte Adhesion Molecule-deficient (ICAM-1/-) MICE. Society for the Study of Reproduction, 36th Annual Meeting, Cincinnati, Ohio (19-22 July 2003) Norman RJ Ovulation Induction and Assisted Reproduction. The Endocrine Society's 85th Annual Meeting. Philadelphia USA (19-22 June 2003) Norman RJ, Moran L, Noakes M, Clifton P, Wittert G. Ghrelin secretion following weight loss and different dietary composition in PCOS ­ evidence of impaired response. Endocrine Society's 85th Annual Meeting, Philadelphia June 19-22 2003. RJ Norman. "Programming of Reproductive Function: Polysystic Ovar Syndrome". Second World Congress on Fetal Origins of Adult Disease. United Kingdom (7-10 June 2003)

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Norman RJ. Metformin. PCOS workshop (ASRM/ESHRE sponsored); consensus/controversy update regarding diagnostic criteria and long-term health risks. Rotterdam, The Netherlands (14 May 2003) Norman RJ. Insulin-sensitizing agents for PCOS ­ do they work? Endocrine Society of Australia Annual Seminar Meeting for Physicians and Scientists. Noosa Qld (2003) 2002 Hickey TE, Marrocco DL, Gilchrist RB, Ritter LJ, Norman RJ, Armstrong DT. Differential androgen response between mural and cumulus granulosa cells in the pig ovary. (Proc. 2002, Sep) Australian Society for Medical Research, Adelaide, Australia. Gilchrist RB, Pritchard L, Amato F, Armstrong DT and Norman RJ. (2002) Characterisation of the Role of FSH in the Marmoset Monkey : Comparison of FSH Levels in Natural Cycles, Prostaglandin-F2a-Regulated Cycles and Socially Subordinate Animals. Society for the Study of Reproduction, Baltimore USA. Bill. Reprod. 66 (Suppl 1) : 449 Hickey TE, Gilchrist RB, Ritter LJ, Norman RJ, Armstrong DT. (2002) In vitro effects of 5-adihydrotestosterone on granulosa cells from gilts: differential response between mural granulosa cells and cumulus-oocyte complexes. Society for the Study of Reproduction, Baltimore, USA. Biol. Reprod. 66 (Suppl 1) : 11. Pritchard L, Amato F, Gilchrist RB, Armstrong DT and Norman RJ. (2002) Development of a Marmoset FSH Assay Using an Antibody Raised Against Recombinant marmoset FSH and Examination of the Role of FSH in Socially Subordinate Monkeys. Proc. US Endocrine Society, USA. P1-144. Gilchrist RB, Amato F, Pritchard L, Scott SJ, Ritter LR, Armstrong DT, Norman RJ. Role of FSH in social suppression of fertility in marmoset monkeys. (Proc. 33rd Ann. Conf. SRB, Adelaide, Australia). (Sep 2002)

2001 Norman RJ. Immune dysregulation and ovarian disorders. Australian Academy of Science Boden Research Conference, Lorne, Australia (2001). Norman RJ. Why have a Quality Management System in Reproductive Medicine? Quality Management Systems in Reproductive Medicine , Adelaide (2001). Sturgeon C, Stenman U-H, Birken S, Bidart J-M, Berger P, LequinRM, Norman RJ, Bristow A. Report of the IFCC Working Group on Standardisation of Human Chorionic Gonadotrophin Measurements. IFCC EuroMedLab meeting, Prague (2001). 2000 Clark AM, Roberts B. Galletly C, Tomlinson L. Norman RJ. Maximizing weight loss in the overweight infertile patient -­a prospective randomized controlled trial. 15th Annual Meeting European Society of Human Reproduction and Embryology. Bologna (2000). Davies MJ, Wang XJ, Norman RJ. The influence of body mass on fecundity of women during assisted reproduction treatment. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000).

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Duggal PS, Armstrong DT, Magoffin DA, Norman RJ. The in vivo effect of leptin and feed restriction on rat ovarian leukocytes. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April 29 (2000). Duggal PS, Armstrong DT, Magoffin DA, Norman RJ. Leptin and feed restriction affects rat ovarian neutrophils (N) and monocyte/macrophages (M). 11th International Congress of endocrinology ICE 2000, Sydney 29th Oct - 2nd Nov (2000). Flight IHK, Reese MCP, Norman RJ. Does HRT cause weight gain? A systematic review of the evidence. International Menopause Meeting. Yokohoma, Japan (2000). Gilchrist RB, Ritter LJ, Rowe DB, Fujii S, Norman RJ, Robertson SA, Armstrong DT. Differential expression of GM-CSF receptor mRNA subunits in follicular cells and the effect of GM-CSF deficiency on oocyte meiotic competence. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000). Norman RJ. Insulin modifying approaches. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000) Norman RJ. Clinical management of premature ovarian dysfunction. 4th Australasian Menopause Society Annual Congress, Adelaide (2000). Norman RJ, Kirby C, Thompson J. Pregnancy following ICSI of the wrong sperm - DE NOVO mutation or public relations disaster? Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000) Norman RJ, Milner C, Groome N. Robertson D. Serum follistatin concentrations are increased and activin A concentrations are decreased in PCOS. 15th Annual Meeting European Society of Human Reproduction and Embryology (Bologna) (2000). Robson S, Barry M, Norman RJ. Assessment of ovarian follicular vascularity by power doppler sonography during transvaginal oocyte retrieval in IVF cycles - a pilot study. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000). Tremellen KP, Valbuena D, Landeras J, Ballesteros A, Martinex J, Mendoza S, Robertson SA, Simon C, Norman RJ. The effect of intercourse on pregnancy rates during assisted human reproduction. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000). Wang XJ, Davies MJ, Norman RJ. The influence of body mass index (BMI) on pregnancy wastage following initial ART success. Proc 31st Annual Conference of the Fertility Society of Australia/Australian Society for Reproductive Biology. Canberra 26-30 April (2000). 1999 Alvino HJ, Davies TG, Norman RJ. An early menopause clinic in a reproductive medicine unit. 11th World Congress on In Vitro Fertilisation and Human Reproductive Genetics, Sydney, May 914 (1999) Abstract P-261). Amato F, Hickey t, Simula AP, Graham L, Armstrong DT, Gilchrist RB, Norman RJ. Recombinant marmoset follicle stimulating hormone (FSH): expression in baculovirus-insect cells, purification and characterization. Proc. 42nd Annual Scientific Meeting of the Endocrine Society of Australia, Melbourne, Sept 26-29 (1999). (Suppl): 123.

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Claman P, Norman RJ, Berga SL. Weight and Reproductive Function. American Society for Reproductive Medicine Canadian Fertility and Andrology Society. Conjoint Annual Meeting, Toronto, Canada. Sept 25-30 (1999). Duggal PS, Hussey ND, Norman RJ. Detection of rat leptin receptor (Isoform B) MRNA in rat ovary using a semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) assay. Australian Society for Reproductive Biology. Melbourne. Sept 26-29 (1999). Duggal PS, Van der Hoek KH, Milner CR, Magoffin DA, Norman RJ. The in vivo effect of leptin on ovulation in the rat. 42nd Annual Scientific Meeting of the Endocrine Society of Australia, Melbourne, Sept 26-29 (1999). Duggal PS, Van der Hoek KH, Milner CR, Magoffin DA, Norman RJ. The in vivo effect of leptin on ovulation in the rat. North Western Adelaide Health Service Research Day (1999). Flight IH, Norman RD, Reese MJ. HRT and weight. A systematic review of the evidence. Proceedings of the 3rd Australasian Menopause Conference, Cairns (1999) Flight IHK, Rees MCP, Norman RJ, Does HRT cause weight gain? A systematic review of the evidence. 9th International Menopause Association Congress, Japan (1999). Gilchrist RB, Ritter LJ, Norman RJ, Armstrong DT. Changes in Marmoset Granulosa Cell Responsive-ness to FSH and IGF-1 WITH Follicular Growth. Australian Society for Reproductive Biology. Melbourne 1999. Gilchrist RB, Rowe DB, Ritter LJ, Norman RJ, Armstrong DT. The effect of graulocytemacrophage colony stimulating factor on ovarian follicular cells. J Reprod Fert Abstract Series No. 23:1 (1999). Gilchrist RB, Wicherek M, Nayudu PL, Norman R, Armstrong DT, Hodges JK. Changes in Ovarian Follicle Distribution in the Marmoset Monkey: Relation to Cycle Stage and Age. 11th World Congress on In Vitro Fertilisation and Human Reproduction and Human Reproductive Genetics, Sydney. May 9-14 (1999). Latimer J, Mau V, Robertson S, Norman R. Cytokine mRNA analysis by RT-PCR in the normal ovary and in ovarian neoplasia. Annual Scientific Meeting Royal Australian & New Zealand College of Obstetricians & Gynaecologists. Adelaide, Feb 28-March 4 (1999). McDonald J, Wang J, NormanRJ. Perinatal outcomes following ovarian hyperstimulation syndrome (OHSS) in IVF pregnancies. 11th World Congress on In Vitro Fertilization and Human Reproductive Genetics, Sydney, May 9-14 (1999). Norman RJ. IUI-An overview. World Congress on Practical Infertility Management, Mumbai, India. Sept 10-12 (1999). Norman RJ. Obesity and infertility. World Congress on Practical Infertility Management, Mumbai, India. Sept 10-12 (1999). Norman RJ. Embryo transfer techniques. World Congress on Practical Infertility Management, Mumbai, India. Sept 10-12 (1999). Sturgeon C, Stenman U-H, Birken S, Bidard J-M, Berger P, Lequin RM, Norman RJ, Bristow A. Report of the IFCC working group on standardisation of human chorionic gonadotropin measurements. IFCC conference, Florence, June 1999. Latimer J, Mau V, Roberston S, Norman R. Cytokine mRNA analysis by RT-PCR in the normal

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ovary and in ovarian neoplasia. Annual Scientific Meeting Royal Australian & New Zealand College of Obstetricians & Gynaecologists, Adelaide, Feb 28- Mar 4, 1999 1998 Latimer J, Mau C, Robertson S, Norman RJ. Cytokine messenger RNA analysis by RT-PCR in the normal ovary and in ovarian tumours. British Gynaecological Cancer Society, 1998 Spring Meeting, Leeds, UK. Latimer J, Norman RJ. Cytokine messenger RNA analysis by ribonuclease protection assay (RPA) in the normal ovary and in ovarian tumours. British Gynaecological Cancer Society, 1998 Autumn Meeting, Leicester, UK. Norman RJ. Leukocytes and cytokines: the missing initiators of normal and abnormal ovulation. International meeting on Ovarian Hyperstimulation Syndrome ­ 1998 Valencia, Spain. Norman RJ. How should eligibility for assisted reproduction be assessed in controversial circumstances? XVII Annual Scientific Meeting of the Fertility Society of Australia. Hobart, 1998. Norman RJ. Early Menopause. Royal Australian College of Obstetricians & Gynaecologists Annual Scientific Meeting. Canberra 1998. Norman RJ. Weight and Fertility. Family Planning Australia Inc. Biological Sciences Meeting. Canberra 1998. Norman RJ. Pregnancy Outcome after Assisted Conception. Royal Australian College of Obstetricians & Gynaecologists Annual Scientific Meeting. Canberra 1998. Norman RJ. The metabolic disturbance of polycystic ovary syndrome. The Endocrine Society of Australia Postgraduate Seminar Meeting. Adelaide 1998. Stenman U-H, Bidert J-M, Birken S, Sturgeon CM, Berger P, Lequin R, Norman RJ. IFCC Working Group for hCG: Progress report. EQAS/ELAS 98 Joint Meeting of the UK National External Quality Assessment Schemes for Endocrinology (UK/NEQAS) and the European Ligand Assay Society (ELAS) Edinburgh April, 1998. 1997 Amato F, Simula AP, Gameau LJ, Norman RJ. Development of a specific and sensitive ELISA for marmoset chorionic gonadotropin. XVI Annual Scientific Meeting of The Fertility Society of Australia. Adelaide 1997 Bonello N, Lomas J, Norman RJ. Periovulatory expression of ICAM-1, VACM-1, E-selectin and P-selectin MRNA in the rat ovary. XVI Annual Scientific Meeting of The Fertility Society of Australia. Adelaide 1997 Bonello N, Norman RJ. Expression of leukocyte-endothelial adhesion molecules in the rat ovary across the periovulatory period. Proceedings of the Twenty-Eighth Conference of the Australian Society for Reproductive Biology, Canberra, Australia, 1997 Clark AM, Ledger W, Galletly C, Tomlinson L, Blaney F, Wang X, Norman RJ. Endocrine Society of Australia Clinical Weekend, Canberra, Australia Sept. 1997 Gameau LJ, Lopata A, Norman RJ, Simula AP. Chorionic gonadotrophin-beta expression in trophoblastic vesicles of the marmoset monkey (Callithrix jacchus). Proceedings of the TwentyEighth Conference of the Australian Society for Reproductive Biology, Canberra, Australia, 1997

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Jasper MJ, Norman RJ, Robertson SA. Tissue compartment specific mRNA expression of the GM-CSF cell signalling system in the mouse ovary. Proceedings of the Twenty-Eighth Conference of the Australian Society for Reproductive Biology, Canberra, Australia, 1997 Jasper MJ, Robertson SA Norman RJ. Pseudopregnancy in the mouse is unaltered by granulocyte-macrophage colony-stimulating factor (GM-CSF) gene knockout. XVI Annual Scientific Meeting of The Fertility Society of Australia. Adelaide 1997. Jasper MJ, Robertson SA, Norman RJ. GM-CSF and GM-CSF receptor mRNA in the mouse ovary through the estrous cycle. Proceedings of the Thirtieth Meeting of the Society for the Study of Reproduction, Portland, Oregon. Latimer J, Jones C, Norman RJ. Cytokine protein levels in the serum, ascites and cyst fluid of women with ovarian tumours. British Gynaecological Cancer Society. 1997 Autumn Meeting, Bristol, UK. Masters L, Norman RJ. Polycystic ovary syndrome and glucose tolerance: a five year follow-up study. XVI Annual Scientific Meeting of The Fertility Society of Australia. Adelaide 1997 Milner CR, Craig JE, Norman RJ. The frequency of the LH beta subunit genetic variant and its association with polycystic ovary syndrome. XVI Annual Scientific Meeting of The Fertility Society of Australia. Adelaide 1997 Norman RJ. Pregnancy testing. Australasian Association of Clinical Biochemists & Royal College of Pathologists of Australasia, Adelaide 1997. Norman RJ. Polycystic Ovaries and Anovulation. Endocrine Society of Australia Clinical Weekend, Canberra, Australia Sept. 1997 Norman RJ, Clark AM. Obesity and Reproductive Disorders. Genes and Environment in Human Reproductive Disorders International Symposium, Serono Colloquia Australia, Adelaide 1997. Norman RJ, Flight I. Weight and HRT. The 1st Australasian Menopause Society Congress, Perth 1997. Norman RJ, Milner C, Hussey N, Craig. Prevalence and significance of polymorphisms of tumour necrosis factor in PCOS. 13th Annual Meeting European Society of Human Reproduction & Embryology (Edinburgh 1997). Shinetugs B, Bonello NP, Norman RJ. Serum levels of colony stimulating factor-1 across the menstrual cycle. NWAHS Research Day 97. Van der Hoek KH, Woodhouse CM, Van Rooijen N, Maddocks S, Norman RJ. The effect of intrabursal injection of liposome encapsulated dichloromethylene diphosphate (CI2MDP) on ovulation in the mouse. Proceedings of the Twenty-Eighth Conference of the Australian Society for Reproductive Biology, Canberra, Australia, 1997 1996 Bonello N, Norman RJ. Menstrual cyclicity of soluble cell adhesion molecules in human serum. NWAHS Research Day 1996. Craig JE, Milner CR, Norman RJ. Genetic association studies in the polycystic ovary syndrome using polymorphisms in the CYP-17 and LH- genes. The Fertility Society of Australia XV Annual Scientific Meeting (Queenstown, NZ 1996),

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Gameau J, Lopata A, Norman RJ, Simula AP. Chorionic gonadotrophin expression in early primate embryos. . NWAHS Research Day 96. Gameau J, Lopata A, Norman RJ, Simula AP. Chorionic gonadotrophin expression in early primate embryos. 39th Annual Scientific Meeting Endocrine Society of Australia (New Zealand) 1996. Graham LA, Norman RJ, Simula AP. The expression of recombinant marmoset follicle stimulating hormone using the baculovirus expression vector system. . NWAHS Research Day 96. Hoy WE, Rees M, Kile E, Norman RJ, Matthews JD. Low birth weight and insulin resistance. First Int Conf on the Prevention of Diabetes and its Complications, Copenhagen, April 24-29, 1996. Jasper MJ, Norman RJ, Robertson SA. Semi-quantitation of GM-CSF and GM-CSF receptor mRNA in the mouse ovary throughout the oestrus cycle. . NWAHS Research Day 96. Jasper MJ, McKie KH, Robertson SA, Norman RJ. In vitro perfusion of ovaries from GM-CSF deficient mice. . 39th Annual Scientific Meeting Endocrine Society of Australia (New Zealand) 1996. Latimer JA, Norman RJ. The mitotic rates of the rat ovarian surface epithelium (OSE) and peritoneal mesothelium (PM) and the effect on these of gonadotrophin stimulation. Clinical Oncological Society of Australia 1995 Annual Scientific Meeting, Canberra. (Also presented at the British Gynaecological Cancer Society Spring Meeting 1996, Sheffield UK). Norman RJ, Clinical Chemistry and the New Reproductive Technologies. 34th Annual Scientific Meeting and QC Update 1996 (Darwin). Norman RJ. The indications for, and appropriate use of, Testosterone in hormone replacement therapy". A forum conducted 6th December 1994 by Adelaide & Dale Street Women's Health centres. Published April 1996 Norman RJ, Bacich D, Bonello N, Jasper M, McKie K, Robertson SA, Rodgers RJ. Follicle events following the LH surge. Serono Colloquia Australasia Symposium 1996 (Queenstown, NZ). Norman RJ, Craig J. Hague W, Masters S, Buchholz M. Genetic and environmental origins of polycystic ovary syndrome. The Royal Australian College of Obstetricians & Gynaecologists 1996 Annual Scientific Meeting (Nadi, Fiji) Norman RJ, Buchholz Huber M-M, Carey D, Clark A. Weight loss in anovulatory women is associated with restoration of ovarian function and a decrease in insulin resistance. ICE'96 10th International Congress of Endocrinology (San Francisco, 1996). Simula AP, Gameau LJ, Norman RJ. Messenger RNA splice variants of the beta-subunit of marmoset chorionic gonadotrophin. 39th Annual Scientific Meeting Endocrine Society of Australia (New Zealand) 1996. Shinetugs B, Bonello NP, Norman RJ. Serum levels of colony stimulating Factor-1 across the menstrual cycle. XVI Annual Scientific Meeting of The Fertility Society of Australia. Adelaide 1997 Wang L, Cui KH, Maddocks S, Norman RJ. Type 1 interleukin 1 receptor and interleukin 1 receptor antagonist in the rat ovary and testis detected by in-situ. ICE'96 - 10th International Congress of Endocrinology (San Francisco, 1996).

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1995 Bacich DJ, Rodgers RJ, Earl C, Norman RJ. Is the major alternatively spliced LH receptor mRNA translated in vivo in the ovine ovary? The Queen Elizabeth Hospital Research Day (Adelaide, 1995). Bacich DJ, Norman RJ, Earl CR, Rodgers RJ. The major alternatively spliced LH receptor mRNA is translated in vivo in the ovine ovary. Endocrine Society of Australia 38th Annual Scientific Meeting (Melbourne, 1995). Bacich DJ, Rodgers RJ, Earl C, Norman RJ. Is the major alternatively spliced LH receptor mRNA translated in vivo in the ovine ovary? The Queen Elizabeth Hospital Research Day (Adelaide, 1995). Bonello N, McKie K, Brännström M, Norman RJ. Inhibition of nitricoxide: effects on ovulation rate, steroid hormones and ovarian leukocyte distribution at ovulation in the rat. ASRB 27th Annual Conference (Melbourne, 1995) Bonello N, McKie K, Norman RJ. Inhibition of nitric oxide: effects on interleukin-1b-enhanced ovulation rate, steroid hormones and ovarian leukocyte distribution at ovulation in the rat. The Queen Elizabeth Hospital Research Day (Adelaide, 1995). Gameau LJ, Simula AP, Norman RJ. Quantitation of marmoset CG/LH beta mRNA species in pituitary and placental tissue. ASRB 27th Annual Conference (Melbourne, 1995) Jasper MJ, Norman RJ, Robertson SA. Localization of macrophages and neutrophils in the peri-ovulatory ovary of the normal and GM-CSF deficient mouse using video image analysis. ASRB 27th Annual Conference (Melbourne, 1995) Jasper MH, Norman RJ, Robertson SA. Macrophage and granulocyte localisation in the periovulatory ovary of the normal and GM-CSF deficient mouse. The Queen Elizabeth Hospital Research Day (Adelaide, 1995). McKie KH, Brännström M, Norman RJ. IL-6 does not stimulate ovulation in the in vitro perfused rat ovary. ASRB 27th Annual Conference (Melbourne, 1995) Norman RJ, Wang X, Masters S, Hague W. Subjects with polycystic ovaries without hyperandrogenaemia exhibit similar disturbances in insulin and lipid profiles as those with polycystic ovary syndrome. Endocrine Society of Australia 38th Annual Scientific Meeting (Melbourne, 1995). Norman RJ. Clinical significance of different hCG assays in body fluids of cancer patients. 11th IFCC European Congress of Clinical Chemistry (Tampere, Finland, 1995). Norman RJ, Bonello N, McKie K, Brannstrom M. Leukocyte recruitment and ovulation in-vivo and in-vitro is impaired by inhibition of nitric oxide. XIth Annual Meeting European Society of Human Reproduction and Embryology, Hamburg, Germany, 1995. Norman RJ. Immune-endocrine interactions during ovulation. Superovulation and Oocyte Maturation International Symposium, Serono-Colloquia (Melbourne, 1995). Norman RJ. Pathogenesis of polycystic ovary syndrome. The Fertility Society of Australia XIV Annual Scientific Meeting (Melbourne) 1995. Petrucco O, Phillipson G, Payne D, Flaherty S, Clark A, Kirby C, Norman RJ, Matthews CD. Micro epididymal sperm aspiration (MESA) and intracytoplasmic sperm injection (ICSI). 15th World Congress on Fertility and Sterility, Montpellier-France 1995.

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Simula AP, Amato F, Norman RJ. Purification of 6His-tagged recombinant marmoset choriogonadotrophin using metal affinity chromatography. ASRB 27th Annual Conference (Melbourne, 1995) Wang LJ, Brännström M, Cui K-H, Simula AP, Hart RP, Maddocks S, Norman RJ. Localization of gene expression of interleukin-1 receptor and interleukin-1 receptor antagonist in the rat ovary. ASRB 27th Annual Conference (Melbourne, 1995) Wang LJ, Norman RJ, Cui K-H, Maddocks S. Distribution of messenger RNAs for type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in rat testis detected by in-situ hybridization. Endocrine Society of Australia 38th Annual Scientific Meeting (Melbourne, 1995). 1994 Amato F, Simula A, Norman RJ. The purification of marmoset chorionic gonadotrophin (mCG) and the production of anti-mCG antibodies. Endocrine Society of Australia 37th Annual Scientific Meeting (Brisbane, 1994).. Brannstrom M, Jasper M, Payne C, Norman RJ. Menstrual cyclicity of TNF in the human. Endocrine Society of Australia 37th Annual Scientific Meeting (Brisbane, 1994). Brannstrom M, Bonello N, Norman RJ, Robertson S. Reduction of ovulation rate in the rat by administration of a neutrophil-depleting monoclonal antibody. ASRB 26th Annual Conference (Brisbane, 1994).. Clark AM, Wang X-J, Norman RJ. A weight loss group-beneficial effects on pregnancy outcome and endocrine and metabolic parameters. The Fertility Society of Australia XIII Annual Scientific Meeting (Brisbane, 1994). Cui K-H, Haan EA, Clark A, Jeffrey R, Wang L, Norman RJ, Matthews CD. Initial pregnancy (miscarriage) from preimplantation diagnosis of Cystic Fibrosis ( F508). Gilmore TA, Norman RJ. Productivity & Cost Indices in an immunoassay laboratory. Proc AACB, Adelaide (1994). Norman RJ. Polycystic ovary syndrome - aetiology and treatment. Australia 37th Annual Scientific Meeting (Brisbane, 1994). p205 Endocrine Society of

Norman RJ, Hague WM, Masters SC, Wang WJ. Hyperinsulinaemia is more common in male and female family members of subjects with polycystic ovary syndrome (PCOS). Endocrine Society of Australia 37th Annual Scientific Meeting (Brisbane, 1994). Norman RJ, Hague WM, Masters SC, Wang WJ. Apparently normal subjects with polycystic ovaries on ultrasound exhibit similar hormonal and metabolic disturbances as those with polycystic ovary syndrome. The Fertility Society of Australia XIII Annual Scientific Meeting (Brisbane, 1994). Simula A, Amato F, Faast R, Lopata A, Norman RJ. Gonadotrophin structure in the marmoset monkey. The Endocrine Society 76th Annual Meeting (Anaheim, CA, 1994). Wang LJ, Cui KH, Brannstrom M, Norman RJ, Rodgers RJ. Expression of 3B-hydroxy steroid dehydrogenase in early human placenta detected by non-radioactive in-situ hybridization. The Fertility Society of Australia XIII Annual Scientific Meeting (Brisbane, 1994). Wang XJ, Clark AM, Chu I, Ong KL, Stevens HJ, Tremethick SR, Seigberg R, Flaherty S, Norman RJ. IVF and ovulation induction for PCOS patients. The Fertility Society of Australia XIII Annual Scientific Meeting (Brisbane, 1994). 1993

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Bacich DJ, Norman RJ, Rohan RM, Rodgers RJ. Identification and quantitation of alternatively spliced luteinizing hormone receptor mRNA in ovine ovaries. XIII Annual Scientific Meeting, Fertility Society of Australia (1993). Tozawa H, Petrucco O, Walker S, Brannstrom M, Pascoe V, Norman RJ. Laser drilling and changes in white cell distribution in sheep ovaries: an immunohistochemical study. XII Annual Scientific Meeting, The Fertility Society of Australia (1993). 1992 Bacich DJ, Norman RJ, Rohan RM, Rodgers RJ. Quantitation of luteinizing hormone receptor messenger RNA species within the ovine ovary. Proceedings of the 24th Annual Conference of Australian Society for Reproductive Biology, Adelaide. (1992). Rayner T, Chen Bao Nan, McLoughlin J, Menadue M, Norman R, Oliver J. The stimulation of atrial natriuretic factor secretion from the isolated rat heart by platelet-activating factor is mediated by the production of prostaglandin F2_. Proceedings of the 35th Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide. (1992). Jasper M, Brännström M, McLoughlin J, Norman R. Menstrual cyclicity of plasma cytokines in the human. Proceedings of the 35th Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide. (1992). Wang LJ, Brännström M, Pascoe M, Norman RJ. Cellular composition of primary cultures of human granulosa-lutein cells and the effect of cytokines on cell proliferation. Proceedings of the 35th Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide. (1992). Brännström M, Wang LJ, Norman RJ. Stimulatory effects of cytokines on the ovulatory process in the rat ovary perfused in vitro. Proceedings of the 35th Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide. (1992). Bonello N, Norman R, Brännström M. Regulation of plasminogen activator activity and synthesis of progesterone and prostaglandin E by LH and IL-1ß in rat preovulatory follicles. Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. (1992). Jasper MJ, Brännström M, Petrucco O, Robertson S, Norman RJ. Ovarian production of granulocyte-macrophage colony stimulating factor (GM-CSF). Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. 1992). Gilmore TA, Norman RJ. Evaluation of a fully automated enzyme immunoassay for oestradiol. Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. (1992). McLoughlin JW, Goodchild KS, Norman RJ. 'Finger-Prick': An alternative to venepuncture for the assessment of endocrine profiles in women. Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. (1992). Warnes GM, Kirby CA, Clark AM, Petrucco OM, Norman RJ, Matthews CD. Two oocytes electively at gift: effect on single and multiple pregnancy rate. Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. (1992). Wang J, Masters S, Beng C, Hague W, Norman RJ. Metabolic classification of polycystic ovary syndrome using cluster analysis. Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. (1992). Payne C, Norman RJ, Brännström M, Robertson, S, Seamark RF, Petrucco OM. Proceedings of the XIth Annual Scientific Meeting of Fertility Society of Australia, Adelaide. (1992). 1991

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Wang L, Robertson S, Seamark R, Norman RJ. Lymphocytes in human corpus luteum and the effects of lymphokines on ovarian steroidogenesis. 7th meeting of ESHRE, Paris (1991) DeMedeiros S, Amato F, Wang L, Norman RJ. Distribution of hCG beta core in body fluids. Proceedings of Endocrine Society of USA, Washington DC. (1991) 1990 Norman RJ, Wang L, Robertson S, Seamark R. Interleukin 2, but not interleukin 1, inhibits the human chorionic gonadotrophin induced stimulation of progesterone in human luteinized granulosa cells. Proceedings of the Endocrine Society of Australia, Perth. 33:24 (1990) Mahabeer S, Jialal I, Naidoo C, Norman RJ. Insulin and C-peptide secretion in non-obese patients with polycystic ovary syndrome. Proceedings of the Endocrine Society of Australia, Perth. 33:27 (1990) Kirby CA, Godfrey B, Warnes GM, Flaherty S, Norman RJ, Matthews C. In vitro fertilization and gamete intrafallopian transfer following failed donor insemination. Proceedings of Fertility Society of Australia, Perth. Poster No 4 (1990) Norman RJ, Wang L, Shand K. Concentrations of oestradiol, progesterone, 17 hydroxyprogesterone and interleukin 2 in peripheral blood of patients with normal and ectopic pregnancy. Proceedings of Fertility Society of Australia, Perth. (1990) Norman RJ, Buck R, Naidoo S, Wehmann R. Disappearance of hCG and its subunits following surgery for ectopic pregnancy. Proceedings of the Fertility Society of Australia, Perth. (1990) McLoughlin JW, Gilmore TA, Norman RJ. An evaluation of commercially available 17ß oestradiol methods for use in an IVF program compared with a chromatography reference method. Proceedings of the Fertility Society of Australia, Perth. (1990) Warnes GW, Kirby CA, Norman R, Hague W, Petrucco O, Matthews CD. Embryo transfer as a cause of failed IVF. Proceedings of the Fertility Society of Australia, Perth. (1990) 1989 Norman RJ, Buck RH. Immunoactive hCG beta core (hBC) is increased in the urine of patients with carcinoma of the cervix and primary and secondary carcinoma of the liver. Proceedings of the International Symposium on Glycoprotein Hormones, Newport Beach California. (1989) Mahabeer S, Jialal I, Norman RJ. Hyperinsulinemia and hyperlipidemia in non-obese patients with polycystic ovarian syndrome. Proceedings of the Endocrine Society of Australia, Melbourne. 32:167 (1989) Norman RJ, de Medeiros S, Buck RH, Amato F. Urinary beta core fragment of human chorionic gonadotrophin-purification, measurement and clinical applications. Proceedings of Endocrine Society of Australia, Melbourne. 32:191 (1989) Norman RJ, Mahabeer S, Naidoo S, Jialal I. Aetiology and significance of abnormalities of carbohydrate homeostasis in patients with polycystic ovary syndrome. Proceedings of Fertility Society of Australia, Canberra. (1989) Warnes GM, Norman R, Gilmore TA, Matthews CD. The dynamics of luteinizing hormone in the presence of human chorionic gonadotrophin during controlled ovarian hyperstimulation. Proceedings of Fertility Society of Australia, Canberra (1989) Wang L, Norman RJ, Warnes GM, Kirby C, Petrucco O, Matthews C. Follicular and early luteal function in ectopic and multiple pregnancies following hyperstimulation of IVF/GIFT. Proceedings of Fertility Society of Australia, Canberra. (1989)

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Norman RJ, Gilmore TA, McLoughlin J. A simple bedside quantitative assay for hCG compared with standard immunoradiometric, immunoenzymetric and chemiluminescent assays. Proceedings of Fertility Society of Australia, Canberra. (1989) De Medeiros SF, Amato F, Matthews C, Norman RJ. Small molecular components of hCG and LH in urine of pregnant and menopausal women. Proceedings of Fertility Society of Australia, Canberra. (1989) Matthews C, Warnes GM, Kirby CA, Norman RJ, Petrucco OM, Phillipson G, Hague W. The flare effect. Further experience with leuprolide for IVF/GIFT. Proceedings of Fertility Society of Australia, Canberra. (1989) Norman RJ, Warnes GW, Kirby C, Wang X, Matthews C. Luteal phase function following the use of gonadotropin-releasing hormone agonist. Proceedings of Fertility Society of Australia, Canberra. (1989) 1988 Constantinides CG, Norman RJ, Reddi K. Intersex: the influence of laboratory and other investigation findings in the selection of surgical management. Congress of Paediatric Surgeons, Tygerberg, Cape Town (1988) Gihwala N, Buck RH, Joubert SM, Norman RJ. Detection of urinary human chorionic gonadotrophin by rapid immunoconcentration method is the first-line test for suspected ectopic pregnancy. Proceedings of the 24th SA Society of Obstetrics & Gynaecology Congress. Sun City, Bophuthatswana. (April, 1988) Norman RJ, Buck RH, Joubert SM. Bioactive hCG in ectopic pregnancy. Proceedings of the 24th SA Society of Obstetrics & Gynaecology Congress. Sun City, Bophuthatswana. (April, 1988) Norman RJ, Mahabeer S, Naidoo C, Jialal I, Joubert SM. Carbohydrate disturbances in polycystic ovarian syndrome. Proceedings of the 24th SA Society of Obstetrics & Gynaecology Congress. Sun City, Bophuthatswana. ((April, 1988) Norman RJ, Pegoraro R, Joubert SM. Prolactin receptors in human breast cancer. Proceedings of the 24th SA Society of Obstetrics & Gynaecology Congress. Sun City, Bophuthatswana. (April, 1988) Padayachi T, Pegoraro RJ, Joubert SM, Norman RJ. Sex steroid receptors in human pregnancy. Proceedings of Cuthbert Crichton Research Society. Sun City, Bophuthatswana. (April, 1988) 1987 Brock-Utne JG, Gaffin SL, Wells MT, Gathiram P, Sohare E, James MF, Morrell DF, Norman RJ, Bosenberg AT. Endotoxaemia in exhausted Comrade's runners. Proceedings of the 2nd SA Sports Medicine Congress, Cape Town (1987) Buck RH, Gihwala N, Joubert SM, Norman RJ. Detection of urinary human chorionic gonadotrophin by rapid immunoconcentration method is the first-line test for suspected ectopic pregnancy.. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Buck RH, Norman RJ, Joubert SM. The Tandem Icon urine test for chorio-gonadotropin (hCG) in ectopic pregnancy. Abstract 043. 39th National Meeting of the American Association of Clinical Chemistry, San Francisco, USA (1987) Buck RH, Norman RJ, Joubert SM. The early diagnosis of ectopic pregnancy. Seminar Hybritech Inc., San Diego, USA (1987)

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Buck RH, Pather N, Joubert SM, Norman RJ. Bedside application of an ultrasensitive urine test for human chorionic gonadotropin in patients with suspected ectopic pregnancy. Abstract C9. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Jialal I, Reddi K, Norman RJ. A novel syndrome of hyperandrogenism and insulin resistance in non-obese women with polycystic ovarian disease. American Diabetes Association, Indianapolis, USA (1987) Mahabeer S, Jialal I, Norman RJ, Reddi K, Joubert SM. Insulin resistance in non-obese patients with polycystic ovarian disease: is there a defect in the hepatic extraction of insulin? Abstract C27. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Norman RJ, Coutts P. A field laboratory at the Comrades Marathon. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Abstract C32.

Norman RJ, Coutts P, Slade A. An inexpensive, locally run clinical chemistry quality control programme suitable for smaller and isolated laboratories. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Norman RJ, Reddi K, Joubert SM. An intrinsic defect of prostaglandin F production by amnion in dysfunctional human labour. Abstract 938. Endocrine Society, Indianapolis, USA (1987) Reddi K, Norman RJ, Joubert SM. Mobilization of arachidonic acid from the fetal membrane in primary dysfunctional labour. 176th Meeting of the Society for Endocrinology, Bristol, UK (Nov, 1987) Wittenberg DF, Desai RK, Norman RJ, Desai PK. Thyroid function in cord blood from low birthweight infants. Proceedings of the 1st National Workshop on Congenital Hypothyroidism. UCT Medical School, Cape Town (1987) Brock-Utne JG, Gaffin SL, Wells MT, Gathiram P, Sohare E, James MF, Morrell DF, Norman RJ, Bosenberg AT. Endotoxaemia in exhausted Comrade's runners. Proceedings of the 2nd SA Sports Medicine Congress, Cape Town (1987) Buck RH, Gihwala N, Joubert SM, Norman RJ. Detection of urinary human chorionic gonadotrophin by rapid immunoconcentration method is the first-line test for suspected ectopic pregnancy. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Buck RH, Norman RJ, Joubert SM. The Tandem Icon urine test for chorio-gonadotropin (hCG) in ectopic pregnancy. 39th National Meeting of the American Association of Clinical Chemistry, San Francisco, USA (1987) Buck RH, Norman RJ, Joubert SM. The early diagnosis of ectopic pregnancy. Seminar Hybritech Inc., San Diego, USA (1987) Buck RH, Pather N, Joubert SM, Norman RJ. Bedside application of an ultrasensitive urine test for human chorionic gonadotropin in patients with suspected ectopic pregnancy. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Jialal I, Reddi K, Norman RJ. A novel syndrome of hyperandrogenism and insulin resistance in non-obese women with polycystic ovarian disease. American Diabetes Association, Indianapolis, USA (1987) Mahabeer S, Jialal I, Norman RJ, Reddi K, Joubert SM. Insulin resistance in non-obese patients with polycystic ovarian disease: is there a defect in the hepatic extraction of insulin? Proceedings of the SA Society of Pathologists, Johannesburg (1987) Norman RJ, Coutts P. A field laboratory at the Comrades Marathon. Proceedings of the SA Society of Pathologists, Johannesburg (1987)

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Abstract C32.

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Norman RJ, Coutts P, Slade A. An inexpensive, locally run clinical chemistry quality control programme suitable for smaller and isolated laboratories. Proceedings of the SA Society of Pathologists, Johannesburg (1987) Norman RJ, Reddi K, Joubert SM. An intrinsic defect of prostaglandin F production by amnion in dysfunctional human labour. Endocrine Society, Indianapolis, USA (1987) Reddi K, Norman RJ, Joubert SM. Mobilization of arachidonic acid from the fetal membrane in primary dysfunctional labour. 176th Meeting of the Society for Endocrinology, Bristol, UK (Nov, 1987) Wittenberg DF, Desai RK, Norman RJ, Desai PK. Thyroid function in cord blood from low birthweight infants. Proceedings of the 1st National Workshop on Congenital Hypothyroidism. UCT Medical School, Cape Town (1987) 1986 Boulle M, Buck RH, Norman RJ. Avoid a maternal death - detect an ectopic pregnancy. Medical Laboratory Congress, Cape Town (1986) Buck RH, Reddi K, Joubert SM, Norman RJ. Monoclonal antibody-based tests for urine hCG in the diagnosis of ectopic pregnancy. Proceedings of the S A Society of Pathologists, Cape Town (1986) Constantinides CG, Norman RJ, Reddi K. Intersex: the influence of laboratory and other investigation findings in the selection of surgical management. Proceedings of 7th Biennial Congress of the SA Association of Paediatric Surgeons, Stellenbosch (1986) Coutts P, Norman R. A field laboratory at the Comrades Marathon. Abstract P2. Proceedings of the S A Med Tech Congress, Cape Town (1986) Coutts PB, Slade A, Norman RJ. An inexpensive, locally run clinical chemistry quality control programme suitable for smaller and isolated laboratories. Medical Technology Congress, Cape Town (1986) Norman RJ. The structure and function of glycoprotein hormones. Plenary Lecture. Annual Symposium of the Natal Region of the Biochemical Society of South Africa, Pietermaritzburg (1986) Norman RJ. Regulation of prostaglandin production in late pregnancy. Invited lecture of 24rd SA Congress of Obstetrics & Gynaecology, Medunsa (1986) Norman RJ. New advances in the measurement of hCG and its clinical applications. Invited lecture of 23rd SA Congress of Obstetrics & Gynaecology, Medunsa (1986) Norman RJ, Buck RH, Haneef R, Rom L, Joubert SM. Monocolonal antibody-based immunoradiometric assays for the urinary beta core of hCG and its free subunit. SEMDSA Congress, Cape Town (1986) Norman RJ, Buck RH, Pather N, Gihwala N, Joubert SM. Urinary excretion of human chorionic gonadotropin in ectopic pregnancy. Cuthbert Crichton Research Society, Onderstepoort (1986) Norman RJ, Buck RH, Reddi K, Joubert SM. Ultrasensitive urine assays reliably detect the hCG secreted by ectopic pregnancy. Proceedings of the 24th British Congress of Obstetrics and Gynaecology, Cardiff, UK (1986) Norman RJ, Reddi K, Deppe WM, Kemp M, Machattie T, Joubert SM. Arachidonic acid precursor products from normal and delayed labour. Abstract 46. 23rd SEMDSA Congress, Cape Town (1986)

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Norman RJ, Reddi K, Deppe WM, Kemp M, Machattie T, Joubert SM. An intrinsic defect in prostaglandin F characterizes dysfunctional labour in the multiparous patient. Cuthbert Crichton Research Society, Onderstepoort (1986) Padayachi T, Norman RJ, Pegoraro R, Joubert SM. Oestrogen and progesterone receptor concentrations in pregnant and nonpregnant tissue. Abstract 70. 23rd SEMDSA Congress, Cape Town (1986) Patel F, Reddi K, Kemp M, Joubert SM, Norman RJ. Sensitive urine tests and human chorionic gonadotrophin secreted during ectopic pregnancy. 23rd S A Congress of Obstetrics & Gynaecology, Medunsa (1986) Reddi K, Norman RJ, Deppe WM, Machatti T, Joubert SM. Mobilisation of arachidonic acid and prostaglandin production by the fetal membranes in normal and delayed labour. Proceedings of the S A Society of Pathologists, Cape Town (1986) Richards A, Moodley J, Norman R. The use of low dose aspirin in pregnancy-induced hypertension. 23rd S A Congress of Obstetrics & Gynaecology, Medunsa (1986) 1985 Norman RJ, Buck R, Lowings C, Chard T. New assays for human chorionic gonadotropin. Proceedings South African Society of Pathologists. Johannesburg (1985) Norman RJ, Lowings C, Oliver T, Chard T. Human chorionic gonadotropin in male patients with tumours of the genital tract. Proceedings of 22nd Congress for the Society for Endocrinology, Metabolism & Diabetes of Southern Africa (1985) Norman RJ, Lowings C, Oliver T, Chard T. HCG as a thyroid stimulator in testicular carcinoma. Proceedings South African Society of Pathologists. Johannesburg (1985) Norman RJ, Poulton T, Gard T, Chard T. Monoclonal antibodies to human chorionic gonadotropin: antigenic mapping, immunoradiometric assays and clinical implications. Proceedings of 22nd Congress for the Society of Endocrinology, Metabolism & Diabetes of Southern Africa (1985) 1984 Padayachi T, Norman RJ, Reddi K, Joubert SM. labour. SA Path Cong, Durban. (1984) Amniotic fluid prostaglandins in induced

Meineke KR, Sadhabiriss A, Norman RJ. Amniotic fluid phospholipids: effects of storage and blood contamination. Proc Int Ass of Med Lab Technologists, Australia. (1984) Moodley J, Reddi K, Norman RJ. Amniotic fluid prostanoids in pre-eclampsia. IV World Cong Int Soc for Study of Hypertension in Preg, Amsterdam. (1984) Moodley J, Reddi K, Norman RJ. Decreased central venous concentrations of immunoreactive prostaglandins, 6-keto, F1-alpha, E and F in eclampsia. IV World Cong Int Soc for Study of Hypertension in Preg, Amsterdam. (1984) Norman RJ, Joubert SM, Marivate M. Amniotic fluid phospholipids and glucocorticoids in multiple pregnancy. Obstet Gyn Digest p2 (Dec 1984) Norman RJ, Marivate M, Joubert SM. Human twin pregnancy as a model for the study of endocrine factors responsible for parturition. Physiological development of the fetus and newborn. Int Symp, Oxford. (1984)

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Norman RJ, Reddi K, Kambaran A, Joubert SM, Philpott RH. Decreased concentrations of prostaglandin F2-alpha in delayed labour: a model for studies on the control of prostaglandin production by the uterus. Prostaglandins & Leukotrienes. Int Cong, Washington DC. (1984) Reddi K, Kambaran A, Norman RJ. Abnormalities in prostaglandin F2-alpha in patients with delay in labour. Physiological development of fetus and newborn. Int Symp, Oxford. (1984) Reddi K, Kambaran SR, Norman RJ, Joubert SM, Philpott RH. Abnormal concentrations of prostaglandins in amniotic fluid during delayed labour in multigravid patients. SA Path Cong, Durban. (1984) 1983 Naidoo C, Jialal I, Norman RJ, Rajput MC, Omar MAK. Pituitary function tests in Sheehan's syndrome. Proc Soc Endocr Metab Diab SA. Abstract, Durban (1983) Naidoo C, Norman RJ, Jialal I, Joubert SM, Rajput MC. Sheehan's syndrome. Proc SA Soc Path. Pretoria (1983) Adenohypophyseal function in

Norman RJ. Current concepts in the initiation of labour. Plenary Lecture. Proc SA Soc Obstet Gynaec, Durban (1983) Norman RJ, Joubert SM. Cortisol concentrations in the twin fetus: relationship to the onset of labour and possible regulation by the prostaglandins. Proc SA Soc Path. Pretoria (1983) Norman RJ, Naidoo C, Reddi K. Clinical and endocrine features of patients with isolated gonadotropin deficiency. Proc SA Soc Path. Pretoria (1983) Norman RJ, Naidoo C, Reddi K, Naidoo BN, Khatree MA. Isolated gonadotropin-releasing hormone deficiency: clinical and endocrine features. Proc Soc Endocr Metab Diab SA. Abstract, Durban (1983) Norman R, Reddi K, Kambaran SR, Joubert SM, Philpott RH. An abnormality in production of prostaglandin F2-alpha in delayed labour: a model for the study of endocrine control in parturition. Proc Soc Endocr Metab Diab SA. Abstract, Durban (1983) Reddi K, Norman RJ, Joubert SM. SASOG Meeting, Durban, (1983) Prostaglandins in dysfunctional labour. Plenary Talk,

Tayor F, Moore R, Norman RJ, Omar MAK. Adrenal function in patients with tuberculosis. Proc Soc Endocr Metab Diab SA. Abstract, Durban (1983)

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