Read metohoruminntopioguritazonnnoheiyou.pdf text version

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

metformin pioglitazone 090314

SU HOMA-R 5 ( Actoplus Met )

2 12

3

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

1 HbA1c HbA1c 1. Umpierrez G/Issa M/Vlajnic A Curr Med Res Opin/22 4 751-9 /2006 http://minds.jcqhc.or.jp/stc/0004/4/0004_G0000077_C0002537_0001.html metformin 2 glimepirideSU pioglitazone HbA1c HbA1c 26 (glimepiride 1.30±0.077pioglitazone 1.23±0.073) (P0.4825)pioglitazone glimepiride HbA1c

2.

Tan MH/Gilmore KJ/Eckland DJ/Widel M/Johns D/Ceriello A Diabetes Care/28 2 266-72 /2005 02 http://minds.jcqhc.or.jp/stc/0004/4/0004_G0000077_C0001871_0001.html (oral glucose tolerance test: OGTT)

(composite insulin sensitivity index: CISI) pioglitazonemetformin gliclazideSU metformin incremental AUC CISI (P0.0001)

3.

Rosenstock J/Sugimoto D/Strange P/Stewart JA/Soltes-Rak E/Dailey G

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

Diabetes Care/29 3 554-9 /2006 http://minds.jcqhc.or.jp/stc/0004/4/0004_G0000077_C0002517_0001.html pioglitazone rosiglitazone rosiglitazone metformin (sulfonylurea: SU) 2 glargine rosiglitazone HbA1c glargine 1.66%rosiglitazone 1.51% (P0.1446)HbA1c

4.

Garber A/Klein E/Bruce S/Sankoh S/Mohideen P Diabetes Obes Metab/8 2 156-63 /2006 http://minds.jcqhc.or.jp/stc/0004/4/0004_G0000077_C0002509_0001.html

rosiglitazone metformin 2 metformin-glibenclamide metforminrosiglitazone HbA1c metformin-glibenclamide 1.5%metforminrosiglitazone 1.1% HbA1c ( 0.4%P0.001) HbA1c metforminSU

4 SU PECO PECO Ppatients with type 2 diabetes and glycosylated hemoglobin (HbA1C) levels 8.0% (maximal doses of metformin and an insulin secretagogue) Epioglitazone Cbedtime NPH insulin

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

O Outcome measurements of glycemic control, hypoglycemia, blood pressure, lipid levels, microalbuminuria, and quality of life were assessed at baseline and at 16 weeks. SU 2 nonblinded, open-label, randomized controlled trial ITT 30/31 28/31 HbA1c HbA1c HbA1C levels were lowered to a similar degree in each treatment arm (pioglitazone: ­1.9% ± 1.5%; insulin: ­2.3% ± 1.5%; P 0.32)

4

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

1. 2. 3. 4. Minds . MindsPLUS http://minds.jcqhc.or.jp/stc/0004/4/0004_G0000077_CQ.html . 2 .,. ,2007. 2008 ( 20 )12 . http://www2.takedamed.com/content/search/doc1/114/anzensei/siyou/image/0901act.pdf Aljabri K, Kozak SE, Thompson DM. Addition of pioglitazone or bedtime insulin to maximal doses of sulfonylurea and metformin in type 2 diabetes patients with poor glucose control: a prospective, randomized trial. Am J Med. 2004 Feb 15;116(4):230-5.

ROCKY NOTE

http://rockymuku.sakura.ne.jp/ROCKYNOTE.html

Information

5 pages

Find more like this

Report File (DMCA)

Our content is added by our users. We aim to remove reported files within 1 working day. Please use this link to notify us:

Report this file as copyright or inappropriate

579212


You might also be interested in

BETA