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Kruse Biology 232 Human Anatomy and Physiology II Nervous II - Neurophysiology Lab Objectives Exercise 18A: Neurophysiology of Nerve Impulses: Wet Lab ­ Read only Exercise 18B: Neurophysiology of Nerve Impulses: Computer simulation PhysioEx Exercise 18B: Neurophysiology of Nerve Impulses: Computer Simulation We will be performing all activities. Interactive Physiology CD-ROM 1. The Action Potential 2. The Membrane Potential You will need to complete some of this work outside of class. If you do not have a home computer you may use one in the Open Computer Lab.. Read Laboratory Exercise 18 for background information. We will not be performing the described exercise on the frog sciatic nerve The student should be able to recognize, identify and provide a concise functional definition for each of the following terms and structures.

1. Excitability or irritability 2. Conductivity 3. Resting membrane potential 4. Polarized 5. Sodium ion Na+ 6. Potassium ion K+ 7. Polarized 8. Sodium-potassium pump 9. Threshold stimulus 10. Trigger zone

11. Axon hillock 12. Threshold stimulus 13. Depolarization 14. Threshold potential 15. Action potential 16. Repolarization and hyperpolarization 17. Sodium channels and gates 18. Potassium channels and gates 19. Chloride channels and gates 20. Absolute refractory period 21. Relative refractory period 22. Nerve impulse 23. Excitatory post synaptic potential 24. Inhibitory post synaptic potential 25. Temporal summation 26. Spatial summation 27. Cellular integration 28. Neurotransmitters 29. Facilitators 30. Inhibitors 31. Effector organs 32. Synapses a. Axodendritic b. Axosomatic 2

c. Axoaxonic d. Electrical ­ gap junction e. Chemical 33. Axon terminal 34. Presynaptic neuron 35. Synaptic vesicle 36. Synaptic cleft 37. Postsynaptic neuron 38. Ion channel 39. Synaptic potential/ graded potential/ local potential 40. Chemically gated channels 41. Receptors 42. Electrochemical gradient 43. Depolarize 44. Hyperpolarize 45. Repolarize 46. Threshold 47. Passive (leakage) channel 48. Chemically gated channel 49. Voltage gated channel 50. Second messenger 51. ACh receptor 52. Norepinephrine ­ adrenergic 53. Neurotransmitters 3

a. PNS ­ acetycholine and norepinephrine b. CNS ­ glutamate, glycine and GABA

Complete the objectives at the beginning of the lab exercise. Complete Review Sheet Exercise 18B.

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